Angiotensin II inhibits renin gene transcription via the protein kinase C pathway

Pflugers Archiv European Journal of Physiology

Volumn 444, Issue 4, 2002, Pages 499-505

  Müller, Markus W H ^a   Todorov, Vladimir ^a   Krämer, Bernhard K ^a   Kurtz, Armin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Angiotensin II; As4.1 cell line; Phorbol ester; Protein kinase C; Ren1c promoter

Indexed keywords

4ALPHA PHORBOL DIDECANOATE; ANGIOTENSIN; BISINDOLYLMALEIMIDE; DACTINOMYCIN; HORMONE; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PRORENIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RENIN; TRANSCRIPTION FACTOR AP 1;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVATION; GENE; GENE EXPRESSION; GENE INACTIVATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HORMONE ACTION; JUXTAGLOMERULAR CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN SECRETION; REGULATORY MECHANISM; REN1C GENE; TIME; TRANSCRIPTION REGULATION;

ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; ENZYME INHIBITORS; ENZYME PRECURSORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INDOLES; JUXTAGLOMERULAR APPARATUS; MALEIMIDES; MICE; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; RENIN; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; VASOCONSTRICTOR AGENTS;

EID: 0036452679     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0835-8     Document Type: Article

References (23)

1. Schunkert H, Ingelfinger JR, Jacob H, Jackson B, Bouyounes B, Dzau VJ (1992) Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expression by angiotensin II. Am J Physiol 263:E863-E869
2. Hackenthal E, Paul M, Ganten D, Taugner R (1990) Morphology, physiology, and molecular biology of renin secretion. Physiol Rev 70:1067-1116
3. Holmer S, Rinne B, Eckardt KU, LeHir M, Schricker K, Kaissling B, Riegger G, Kurtz A (1993) Role of renal nerves for expression of renin in adult rat kidney. Am J Physiol 266:F738-F745
4. Matsusaka T, Nishimura H, Utsunomiya H, Kakuchi J, Niimura F, Inagami T, Fogo A, Ichikawa I (1996) Chimeric mice carrying "regional" targeted deletion of the angiotensin type 1A receptor gene. Evidence against the role for local angiotensin in the vivo feedback regulation of renin synthesis in juxtaglomerular cells. J Clin Invest 98:1867-1877
5. Cheng HF, Wang JL, Zhang MZ, Miyazaki Y, Ichikawa I, McKanna JA, Harris RC (1999) Angiotensin II attenuates renal cortical cyclooxygenase-2 expression. J Clin Invest 103:953-961
6. Cheng HF, Wang JL, Wang SW, McKanna JL, Harris RC (1999) Angiotensin converting enzyme inhibitor-mediated increases in renal renin expression are not seen in cyclooxygenase-2 knockout mice (abstract). J Am Soc Nephrol 10:343A
7. Sigmund CD, Okuyama K, Ingelfinger J, Jones CA, Mullins JJ, Kane C, Kim U, Wu CZ, Kenny L, Rustum Y, Dzau VJ, Gross KW (1990) Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct. J Biol Chem 265:19916-19922
8. Jones CA, Petrovic N, Novak EK, Swank RT, Sigmund CD, Gross KW (1997) Biosynthesis of renin in mouse kidney tumor As4.1 cells. Eur J Biochem 243:181-190
9. Laframboise M, Reudelhuber TL, Jutras I, Brechler V, Seidah NG, Day R, Gross KW, Deschepper CF (1997) Prorenin activation and prohormone convertases in the mouse As4.1 cell line. Kidney Int 51:104-109
10. Petrovic N, Kane CM, Sigmund CD, Gross KW (1997) Down-regulation of renin gene expression by interleukin-1β. Hypertension 30:230-235
11. Jensen BL, Lehle U, Müller M, Wagner C, Kurtz A (1998) Interleukin-1 inhibits renin gene expression in As4.1 cells but not in native juxtaglomerular cells. Pflugers Arch 436:673-678
12. Gasc JM, Monnot C, Clauser E, Corvol P (1993) Co-expression of type 1 angiotensin II receptor (AT1R) and renin mRNA in juxtaglomerular cells of the rat kidney. Endocrinology 132:2723-2725
13. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
14. Tamura K, Umemura S, Nyui N, Yabana M, Toya Y, Fukamizu A, Murakami K, Ishii M (1998) Possible role of c-Jun in transcription of the mouse renin gene. Kidney Int 54:382-93
15. Schricker K, Holmer S, Krämer BK, Riegger GAJ, Kurtz A (1997) The role of angiotensin II in the feedback control of renin gene expression. Pflugers Arch 434:166-172
16. Kurtz A, Pfeilschifter J, Hutter A, Bührle C, Nobiling R, Taugner R, Hackenthal R, Bauer C (1986) Role of protein kinase C in the inhibition of renin release caused by vasocon-strictors. Am J Physiol 250:C563-C571
17. Ritthaler T, Della Bruna R, Krämer BK, Kurtz A (1996) Endothelins inhibit cyclic-AMP induced renin gene expression in cultured mouse juxtaglomerular cells. Kidney Int 50:108-115
18. Ritthaler T, Scholz H, Ackermann M, Riegger G, Kurtz A, Krämer BK (1995) Effects of endothelins on renin secretion from isolated mouse renal juxtaglomerular cells. Am J Physiol 268:F39-F45
19. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charon D, Kirilovsky J (1991) The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 266:15771-15781
20. Caroff N, Della Bruna R, Philippe J, Corvol P, Pinet F (1993) Regulation of human renin secretion and renin transcription by quantitative PCR in cultured chorionic cells: Synergistic effect of cyclic AMP and protein kinase C. Biochem Biophys Res Commun 193:1332-1328
21. Chao HS, Poisner A, Poisner R, Handwerger S (1993) Endothelins stimulate the synthesis and release of prorenin from human decidual cells. J Clin Endocrinol Metab 76:615-619
22. Borensztein P, Germain S, Fuchs S, Philippe J, Corvol P, Pinet F (1994) cis-Regulatory elements and trans-acting factors directing basal and cAMP-stimulated human renin gene expression in chorionic cells. Circ Res 74:764-773
23. Chen L-S, Cuddy MP, LaVallette L (1998) Regulation of human renin gene promoter activity: A new negative regulatory region determines the responsiveness to TNFα. Kidney Int 54:2045-2055