Cyclic AMP has distinct effects from Ca2+ in evoking priming and fusion/exocytosis in parotid amylase secretion

Pflugers Archiv European Journal of Physiology

Volumn 444, Issue 5, 2002, Pages 586-596

  Yoshimura, Keiichi ^a   Fujita Yoshigaki, Junko ^b   Murakami, Masataka ^c   Segawa, Akihisa ^d  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^d KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Amylase secretion; Ca2+; Cyclic AMP; Fusion exocytosis; Priming

Indexed keywords

2,4 DINITROPHENOL; AMYLASE; CALCIUM ION; CARBACHOL; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CYCLIC AMP; IONOMYCIN; ISOPRENALINE;

ACINAR CELL; AMYLASE RELEASE; ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; EVOKED RESPONSE; EXOCYTOSIS; NONHUMAN; PAROTID GLAND; PRIORITY JOURNAL; RAT; SECRETORY GRANULE;

2,4-DINITROPHENOL; AMYLASES; ANIMALS; CALCIUM; CARBACHOL; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CHOLINERGIC AGONISTS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; EXOCYTOSIS; ISOPROTERENOL; MALE; MEMBRANE FUSION; PAROTID GLAND; RATS; RATS, WISTAR; SECOND MESSENGER SYSTEMS; SYMPATHOMIMETICS; UNCOUPLING AGENTS;

EID: 0036450832     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0844-7     Document Type: Article

References (22)

1. Bernfeld P (1955) Amylase, α and β. Methods Enzymol 1:149-158
2. Butcher FR, Putney JW Jr (1980) Regulation of parotid gland function by cyclic nucleotides and calcium. Adv Cyclic Nucleotide Res 13:215-249
3. 2+-mediated exocytosis of insulin by activation of protein kinase C. Proc Natl Acad Sci USA 94:4435-4439
4. Fujita-Yoshigaki J (2000) Simulation of regulated exocytosis of amylase from salivary parotid acinar cells by a consecutive reaction model comprising two sequential first-order reactions. J Theor Biol 204:165-177
5. Holz RW, Bittner MA, Peppers SC, Senter RA, Eberhard DA (1989) MgATP-independent and MgATP-dependent exocytosis. J Biol Chem 264:5412-5419
6. McKinney JS, Desole MS, Rubin RP (1989) Convergence of cAMP and phosphoinositide pathways during rat parotid secretion. Am J Physiol 257:C651-C657
7. Merritt JE, Rink TJ (1987) Regulation of cytosolic free calcium in fura-2-loaded rat parotid acinar cells. J Biol Chem 262:17362-17369
8. Möller K, Benz D, Perrin D, Söling H-D (1996) The role of protein kinase C in carbachol-induced, and of cAMP-dependent protein kinase in isoproterenol-induced, secretion in primary cultured guinea pig parotid acinar cells. Biochem J 314:181-187
9. Nauntofte B, Dissing S (1987) Stimulation-induced changes in cytosolic calcium in rat parotid acini. Am J Physiol 253:G290-G297
10. 2+ to prime amylase secretion from permeabilized rat pancreatic acini. Am J Physiol 273:G655-G660
11. Putney JW Jr (1986) Identification of cellular activation mechanisms associated with salivary secretion. Annu Rev Physiol 48:75-88
12. Rubin RP, Adolf MA (1994) Cyclic AMP regulation of calcium mobilization and amylase release from isolated permeabilized rat parotid cells. J Pharmacol Exp Ther 268:600-606
13. Segawa A, Yamashina S (1998) The dynamic of exocytosis of preformed secretory granules from acini in rat salivary glands. Frontiers Oral Biol 10:89-100
14. 2+ response in rat parotid cells. Am J Physiol 276:C1282-C1287
15. Templeton D (1980) Augmented amylase release from rat parotid gland slices in vitro. Pflugers Arch 384:287-289
16. Watson EL, Singh JC, Jacobsen KL (1985) Augmentation of cholinergic-mediated amylase release by forskolin in mouse parotid gland. Life Sci 37:2531-2537
17. Yoshimura K, Nezu E, Yoneyama T (1984) Mechanism of regulation of amylase release by α-and β-adrenergic agonists in rat parotid tissue. Jpn J Physiol 34:655-667
18. Yoshimura K, Nezu E (1991) Dynamic changes in the rate of amylase release induced by various secretagogues examined in isolated rat parotid cells by using column perifusion. Jpn J Physiol 41:443-459
19. Yoshimura K, Nezu E (1992) Interaction between the calcium and cyclic AMP messenger systems in perifused rat parotid acinar cells. Biochem Pharmacol 43:1031-1041
20. Yoshimura K, Hiramatsu Y, Murakami M (1998) Cyclic AMP potentiates substance P-induced amylase secretion by augmenting the effect of calcium in the rat parotid acinar cells. Biochim Biophys Acta 1402:171-187
21. Yoshimura K, Hiramatsu Y (1998) Characteristics of amylase secretion induced by various secretagogues examined in perifused rat parotid acinar cells. Eur J Morphol Suppl 36:198-202
22. i increase but not activation of protein kinase C stimulates exocytosis in rat parotid acini. J Physiol (Lond) 522:403-416