Lack of association between NOTCH3 gene polymorphism and cerebrovascular disease in Japanese patients

Annals of the New York Academy of Sciences

Volumn 977, Issue , 2002, Pages 252-257

  Mizuno, Toshiki ^a   Makino, Masahiro ^a   Fujiwara, Yasuhiro ^a   Nakajima, Kenji ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

CADASIL; Gene; Japanese; NOTCH3; Polymorphism; Stroke

Indexed keywords

NOTCH RECEPTOR; NOTCH3 RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; EXON; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; JAPAN; LEUKOENCEPHALOPATHY; MAJOR CLINICAL STUDY; MULTIINFARCT DEMENTIA;

EID: 0036447699     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04823.x     Document Type: Conference Paper

References (8)

1. Joutel, A., C. Corpechot, A. Ducros et al. 1996. NOTCH3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 383: 707-710.
2. Hutchinson, M., J. O'Riordan, M. Javed et al. 1995. Familiar hemiplegic migraine and autosomal dominant arteriopathy with leukoencephalopathy (CADASIL). Ann. Neurol. 38: 817-824.
3. Artavanis-Tsakonas, S. & P. Simpson. 1991. Choosing cell fate: A view from the Notch locus. Trends Genet. 7: 403-408.
4. Wright, T.R. 1970. The genetics of embryogenesis in Drosophila. Adv. Genet. 15: 261-295.
5. Joutel, A., K. Vahedi, C. Corpechot et al. 1997. Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients. Lancet 350: 1511-1515.
6. Lesnik Oberstein, S.A.J., E. Ferrari, J. Bakker et al. 1999. Diagnostic Notch3 sequence analysis in CADASIL: Three new mutations in Dutch patients. Neurology 52: 1913-1915.
7. Tanizaki, Y., Y. Kiyohara, I. Kato et al. 2000. Incidence and risk factors for subtypes of cerebral infarction in a general population: The Hisayama Study. Stroke 31: 2616-2622.
8. Escary, J.L., M. Cecillon, J. Maciazek et al. 2000. Evaluation of DHPLC analysis in mutational scanning of Notch3, a gene with a high G-C content. Hum. Mutat. 16: 518-526.