Expression of pulmonary lactoferrin in sudden-onset and slow-onset asthma with fatal outcome

Virchows Archiv

Volumn 441, Issue 5, 2002, Pages 494-499

  Tsokos, M ^a   Paulsen, F ^b  

^a UNIVERSITY OF HAMBURG   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

Asthma; Forensic autopsy; Lactoferrin; Slow onset; Sudden onset

Indexed keywords

LACTOFERRIN;

ADOLESCENT; ADULT; AGED; ARTICLE; ASPHYXIA; ASTHMA; BRONCHUS MUCOSA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FATALITY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MORTALITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; ASTHMA; CAUSE OF DEATH; CHILD; CHRONIC DISEASE; DEATH, SUDDEN; FEMALE; FORENSIC MEDICINE; HUMANS; LACTOFERRIN; LUNG; MALE; MIDDLE AGED;

EID: 0036447149     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-002-0666-1     Document Type: Article

References (28)

1. Baynes Rd, Bezwoda WR (1994) Lactoferrin and the inflammatory response. In: Hutchens TW, Rumball SV, Lönnerdal B (eds) Lactoferrin. Structure and function. Plenum Press, New York, pp 133-141
2. Bousquet J, Chanez P, Lacoste JY, Barneon G, Ghavanian N, Enander I, Venge P, Ahlstedt S, Simony-Lafontaine J, Godard P, Michel FB (1990) Eosinophilic inflammation in asthma. N Engl J Med 323:1033-1039
3. Bowes D, Clark AE, Corrin B (1981) Ultrastructural localisation of lactoferrin and glycoprotein in human bronchial glands. Thorax 36:108-115
4. Boxer LA, Coates TD, Haak RA, Wolach JB, Hoffstein S, Baehner RL (1982) Lactoferrin deficiency associated with altered granulocyte function. N Engl J Med 307:404-410
5. Carroll N, Elliot J, Morton A, James A (1993) The structure of large and small airways in nonfatal and fatal asthma. Am Rev Respir Dis 147:405-410
6. Carroll N, Carello S, Cooke C, James A (1996) Airway structure and inflammatory cells in fatal attacks of asthma. Eur Respir J 9:709-715
7. Fahy JV (2001) Remodeling of the airway epithelium in asthma. Am J Respir Crit Care Med 164:S46-S51
8. Fahy JV, Corry DB, Boushey HA (2000) Airway inflammation and remodeling in asthma. Curr Opin Pulm Med 6:15-20
9. Faul J, Tormey V, Leonard C, Burke C, Horne S, Poulter L (1997) Lung immunopathology in cases of sudden asthma death. Eur Respir J 10:301-307
10. Glare EM, Divjak M, Bailey MJ, Walters EH (2001) The usefulness of competitive PCR: Airway gene expression of IL-5, IL-4, IL-4?2, IL-2, and IFN? in asthma. Thorax 56:541-548
11. Jeffery PK (1992) Pathology of asthma. Br Med Bull 48:23-39
12. Jeffery PK, Wardlaw AJ, Nelson FC, Collins JV, Kay AB (1989) Bronchial biopsies in asthma: An ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis 140:1745-1753
13. Jeremy B (1995) Lactoferrin: A multifunctional immunoregulatory protein? Immunol Today 16:417-419
14. Kepley CL, McFeeley PJ, Oliver JM, Lipscomb MF (2001) Immunohistochemical detection of human basophils in postmortem cases of fatal asthma. Am J Respir Crit Care Med 164:1053-1058
15. Kroegel C (1990) The role of eosinophils in asthma. Lung 168[Suppl]:5-17
16. Lamblin C, Gosset P, Tillie-Leblond I, Saulnier F, Marquette CH, Wallaert B, Tonnel AB (1998) Bronchial neutrophilia in patients with noninfectious status asthmaticus. Am J Respir Crit Care Med 157:394-402
17. Lehrer RI, Ganz T, Selsted ME, Babior BM, Curnutte JT (1988) Neutrophils and host defense. Ann Intern Med 109:127-142
18. Masson PL, Heremans JF, Prignot JJ, Wauters G (1966) Immunohistochemical localization and bacteriostatic properties of an iron-binding protein from bronchial mucus. Thorax 21:538-544
19. Oddera S, Silvestri M, Balbo A, Jovovich BO, Penna R, Crimi E, Rossi GA (1996) Airway eosinophilic inflammation, epithelial damage, and bronchial hyperresponsiveness in patients with mild-moderate, stable asthma. Allergy 51:100-107
20. Oseas R, Bullen JJ, Armstrong JA (1979) The role of lactoferrin in the bacterial function of polymorphonuclear leucocytes. Immunology 36:781-791
21. Oseas R, Yang HH, Baehner RL, Boxer LA (1981) Lactoferrin: A promoter of polymorphonuclear leukocyte adhesiveness. Blood 57:939-945
22. Popper HH, Pailer S, Wurzinger G, Feldner H, Hesse C, Eber E (2002) Expression of adhesion molecules in allergic lung diseases. Virchows Arch 440:172-180
23. Roca-Ferrer J, Mullol J, Perez M, Xaubet A, Molins L, de Haro J, Shelhamer J, Picado C (2000) Effects of topical glucocorticoids on in vitro lactoferrin glandular secretion: Comparison between human upper and lower airways. J Allergy Clin Immunol 106:1053-1062
24. Sur S, Crotty TB, Kephart GM, Hyma BA, Colby TV, Reed CE, Hunt LW, Gleich GJ (1993) Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? Am Rev Respir Dis 148:713-719
25. Thompson AB, Bohling T, Heires A, Linder J, Rennard SI (1991) Lower respiratory tract iron burden is increased in association with cigarette smoking. J Lab Clin Med 117:493-499
26. Tonnel AB, Gosset P, Tillie-Leblond I (2001) Characteristics of the inflammatory response in bronchial lavage fluids from patients with status asthmaticus. Int Arch Allergy Immunol 124:267-271
27. Tsokos M, Anders S, Paulsen F, Fehlauer F, Püschel K (2001) Comparative evaluation of pulmonary lactoferrin and lysozyme immunoreactivity for the post-mortem diagnosis of death due to sepsis. Virchows Arch 438:376-381
28. Wardlaw AJ, Dunnette S, Gleich GJ, Collins JV, Kay AB (1988) Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyper-reactivity. Am Rev Respir Dis 137:62-69