Potential efficacy of a delta 5-aminolevulinic acid thermosetting gel formulation for use in photodynamic therapy of lesions of the gastrointestinal tract

Pharmacological Research

Volumn 45, Issue 2, 2002, Pages 159-165

  Bourre, Ludovic ^a   Thibaut, Sonia ^a   Briffaud, Amelie ^a   Lajat, Youenn ^a   Patrice, Thierry ^a  

^a NANTES UNIVERSITY HOSPITAL   (France)

Author keywords

Barrett's oesophagus; Delta aminolevulinic acid; Photodynamic therapy; Protoporphyrin IX; Thermosetting gel

Indexed keywords

AMINOLEVULINIC ACID; POLOXAMER; PROTOPORPHYRIN;

ADHESION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARRETT ESOPHAGUS; CONTROLLED STUDY; DIGESTIVE SYSTEM INJURY; DOSE CALCULATION; DOSE RESPONSE; DRUG EFFICACY; DRUG SCREENING; ESOPHAGUS MUCOSA; FLUORESCENCE; GEL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TEMPERATURE; TIME;

EID: 0036444068     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2001.0934     Document Type: Article

References (26)

1. Barrett N. Chronic peptic ulcer of the oesophagus and oesophagitis. Br J Surg 1950; 38: 175-82.
2. Allison PR, Johnstone AS. The esophagus lined with gastric mucous membrane. Thorax 1953; 8: 87-101.
3. Reid BJ. Barrett's esophagus and esophageal adenocarcinoma. Gastroenterol Clinics North Am 1991; 20: 817-34.
4. Hayata Y, Kato H, Okistu H, Kawaguchi M, Konaka C. Photodynamic therapy with hematoporphyrin derivative in cancer of the upper gastrointestinal tract. Semin Surg Oncol 1985; 1: 1-11.
5. Overholt BF, Panjehpour M. Barrett's esophagus: Photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa and treatment of superficial oesophageal cancer. In: Proc. 5th Int. Photodynamic Association Biennial Meeting, Proc. SPIE. Cortese DA, ed. 1995: 2371: 375-84.
6. Sampliner RE, Hixson LJ, Fennerty B, Garewal HS. Regression of Barrett's esophagus by laser ablation in an acid environment. Dig Dis Sci 1993; 38: 365-8.
7. Bedwell J, MacRobert AJ, Phillips D, Bown SG. Fluorescence distribution and photodynamic effect of ALA-induced PpIX in the DMH rat colonic tumour model. Br J Cancer 1992; 65: 818-24.
8. Kennedy JC, Pottier RH. Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy. J Photochem Photobiol B: Biol 1992; 14: 275-92.
9. Regula J, MacRobert AJ, Gorchein A, Buonaccorsi GA, Thorpe SM, Spencer GM, Hatfield ARW, Bown SG. Photosensitization and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5-aminolevulinic acid induced protoporphyrin IX-a pilot study. Gut 1995; 36: 67-75.
10. Barr H, Shepherd NA, Dix A, Roberts DJ, Tan WC, Krasner N. Eradication of high-grade dysplasia in columnar-lined (Barrett's) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX. Lancet 1996; 348: 584-5.
11. Ackroyd R, Davis MF, Stephenson TJ, Brown NJ, Stoddard CJ, Reed MWR. Photodynamic therapy for Barrett's oesophagus: A prospective randomised placebo-controlled trial. Endoscopy 1997; 29: E17.
12. Kennedy JC, Pottier R, Pross DC. Photodynamic therapy with endogenous protoporhyrin IX: Basic principles and present clinical experience. J Photochem Photobiol B: Biol 1990; 66: 143-8.
13. 15 N. Biochem J 1956; 64: 80-6.
14. El-Far M, Ghoneim M, Ibraheim E. Biodistribution and selective in vivo tumour localization of endogenous porphyrinsinduced and stimulated by 5-aminolevulinic acid: A newly developed technique. J Tumor Marker Oncol 1990; 5: 24-7.
15. Grant WE, Hopper C, MacRobert AJ, Speich PM, Bown SG. Photodynamic therapy of oral cancer: Photosensitization with systemic aminolevulinic acid. Lancet 1993; 342: 147-8.
16. Wolf P, Rieger E, Kerl H. Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulinic acid. J Am Acad Dermatol 1993; 28: 17-21.
17. Robinson PJ, Carruth JAS, Fairris GM, Ash V, Brown SB. Superficial photodynamic therapy with topical 5-aminolevulinic acid for superficial primary and secondary skin cancer. Br J Cancer 1994; 69: 605-8.
18. Vonarx V, Eleouet S, Carre J, Ioss P, Gouyette A, Leray AM, Merle C, Lajat Y, Patrice T. Potential efficacy of a delta 5-aminolevulinic acid bioadhesive gel formulation for the photodynamic treatment of lesions of the gastrointestinal tract in mice. J Pharm Pharmacol 1997; 49: 652-6.
19. Laukka MA, Wang WW, Cameron AJ, Gutta KV, Balm RK. Low dose photodynamic therapy in the treatment of Barrett's oesophagus. Am J Gastroenterol 1993; 88: 1491-4.
20. Overholt BF, Panjehpour M. Barrett's oesophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa and treatment of superficial oesophageal cancer. In: Proc. 5th Int. Photodynamic Association Biennial Meeting, Proc. SPIE. Cortese DA, ed. 1995: 2371: 375-84.
21. Sibille A, Lambert R, Souquet JC, Sabben G, Descos F. Long-term survival after photodynamic therapy for esophageal cancer. Gastroenterology 1995; 108: 337-44.
22. Mlkvy P, Messmann H, Regula J, Conio M, Pauer M, Millson CE, MacRobert AJ, Bown SG, Cortese DA. Sensitization and photodynamic therapy of esophageal, duodenal and colonic tumours with 5-aminolevulinic acid (ALA) induced protoporphyrin IX (PPIX). In: Proc. 5th Int. Photodynamic Association Biennial Meeting, Proc. SPIE. 1995: 2371: 370-4.
23. Overholt BF, Panjehpour M, Haydek JM. Photodynamic therapy for Barrett's esophagus: Follow-up in 100 patients. Gastrointest Endosc 1999; 49: 1-7.
24. Ackroyd R, Brown NJ, Davis MF, Stephenson TJ, Marcus SL, Stoddard CJ, Johnson AG, Reed MWR. Photodynamic therapy for dysplastic Barrett's oesophagus: A prospective, double blind, randomised, placebo controlled trial. Gut 2000; 47: 612-7.
25. Robinson PJ, Carruth JAS, Fairris GM, Ash V, Brown SB. Superficial photodynamic therapy with topical 5-aminolevulinic acid for superficial primary and secondary skin cancer. Br J Cancer 1994; 69: 605-8.
26. Loh CS, Bedwell J, MacRobert AJ, Krasner N, Phillips D, Bown SG. Photodynamic therapy of the normal rat stomach: A comparative study between disulphonated aluminium phthalocyanine and 5-aminolevulinic acid. Br J Cancer 1992; 66: 452-62.