Diabetes mellitus in advanced age - A diabetologist's view

European Journal of Geriatrics

Volumn 4, Issue 4, 2002, Pages 167-172

  Weber, Pavel ^a  

^a UNIVERSITY HOSPITAL BRNO   (Czech Republic)

Author keywords

Aetiopathogenesis; Diabetes mellitus type 2; Diagnostic criteria; Insulin resistance; Late complications

Indexed keywords

ACARBOSE; GLICLAZIDE; GLIPIZIDE; GLIQUIDONE; INSULIN; METFORMIN; MIGLITOL; ORAL ANTIDIABETIC AGENT; ROSIGLITAZONE; TROGLITAZONE;

AGING; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CEREBROVASCULAR DISEASE; DIABETIC ANGIOPATHY; DIABETIC DIET; ENVIRONMENTAL FACTOR; GENETIC PREDISPOSITION; GLUCONEOGENESIS; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULIN SENSITIVITY; INSULIN TREATMENT; LIFESTYLE; LIPID METABOLISM; LIVER TOXICITY; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NUTRITION; PATIENT EDUCATION; PHYSICAL ACTIVITY; PROTEIN METABOLISM; REVIEW; RISK FACTOR; STRESS;

EID: 0036443442     PISSN: 14391147     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (45)

1. Alberti KG, Zimmer PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Diabet Med, 15, 1998: 539-553.
2. Alberti KGMM, de Fronzo RA, Keen H, Zimmet P (Eds.): International Textbook of Diabetes Mellitus. Vol. 1, Vol. 2, New York, 1992, 1729 ff.
3. Anderson DK, Svardsudd K: Long-term glycemic control relates to mortality in type II. Diabetes. Diabetes Care, 18, 1995: 1534-1543
4. Assal JP: Primary Prevention of NIDDM: A future dream. In: Diabetes/Metabolism Review, Vol. 13, No. 2, New York, 1997: 113-117.
5. Bartos V, Pelikánová T a kol.: Praktická Diabetologie. Praha, Maxdorf Jessenius, 2000, 473 ff (in Czech).
6. Berger M, Jörgens V, Chlup R: Lézba Inzulínem v Kazdodenním Zivote. Praha, Victoria Publishing, 1995, 293 ff. (in Czech).
7. Bernstein RK, Aubert TJ, Vinicor F: Dr. Bernstein's Diabetes Solution: A Complete Guide To Achieving Normal Blood Sugars. New York, 1997: 390 ff.
8. Borden G, Chen X, DeSantis RA, Kendrick Z: Effects of age and body fast on insulin resistance in healthy men. Diabetes Care, 16, 1993 728-733.
9. Brückel J: Diabetes Mellitus. In: Nikolaus T (Ed.): Klinische Geriatrie, Berlin, 2000: 450-457.
10. Colwell JA, Bingham SF, Abraira C, et al: Veterans Administration Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: II. Effects of aspirin and dipyridamole on atherosclerotic vascular disease rates. Diabetes Care, 9, 1986, 140-148.
11. Davidson MB: Diabetes mellitus and other disorders of carbohydrate metabolism. In: Abrams WB, Beers MH, Berkow R (Eds.): The Merck Manual of Geriatrics - Second Edition. New York, 1995: 997-1023.
12. De Vegt et al: Hoorn Study. Similar 9 year mortality risks and reproducibility for the WHO and ADA glucose tolerance categories. Diabetes Care, 23, 2000: 40-44.
13. Deerochanawong C, Home PD and Alberti KGMM: A survey of lower limb amputation in diabetic patients. Diabetic Med, 9. 1992: 942-946.
14. Dormandy J, Heeck L, Vig S: Predicting which patients will develop chronic critical leg ischemia. Semin Vasc Surg, 12, 1999: 138-141.
15. Egger M, Smith GD, Stettler C, et al: Risk of adverse effects of intensified treatment in insulin-dependent diabetes mellitus: A meta-analysis. Diabetic Medicine, 14, 1997: 919-928.
16. Finucane P and Sinclair AJ (Eds.): Diabetes in Old Age. New York, 1995: 302 ff.
17. Guillausseau PJ: Dysfunction of b-cells diabetes 2. International Journal of Metabolism, 1, No 27, 1997: 23
18. Gumbiner G, Polonsky KL, Beitz MF et al: Effects of aging on insulin secretion. Diabetes, 38, 1989: 1549-1556.
19. Hall MRP, MacLennan WJ, Lye MDW: Medical Care of the Elderly. New York, 1993.
20. Chlup R, Bruns W: Patofyziologicky prístup k lécbe diabetu 2. typu, Interní medicína pro praxi. 4, 1999: 27-35 (in Czech).
21. Jaap AJ, Jones GC, McCrimmon RJ: Perceived symptoms of hypoglycaemia in elderly type 2. Diabetic patients treated with insulin. Diabetic Medicine, 15, 1998: 398-404.
22. Kahn SE: The pathophysiologic directs of type 2 diabetes, Abnormal insulin action and impaired insulin secretion, Treating Type 2 Diabetes. Postgrad Med - Special Report, May 2000: 11-15.
23. Kaneko T, Takahashi S, Naka T, et al: Postoperative delirium following gastrointestinal surgery in elderly patients, Surg Today, 27, 1997: 107-111.
24. Kath R, Schiel R, Muller UA, et al: Malignancies in patients with insulin-treated diabetes mellitus. J Cancer Res Clin Oncol, 126, 2000: 412-417.
25. Kohrt WM, Kirwan JP, Staten MA, Bourey RE, King DS, Holloszy JO: Insulin resistance in aging is related to abdominal obesity. Diabetes, 42. 1993: 273-281.
26. Lehto S, Ronnemaa T, Pyorala K, Laakso M: Risk factors predicting lower extremity amputations in patients with NIDDM. Diabetes Care, 19, 1996: 607-612.
27. Mandrup-Poulsen T: Recent advances: Diabetes. BMJ, 316, 1998: 1221-1225.
28. Markovic TP, Furler SM, Jenkins AB, Campbell LV, Kraegen EW, Chisholm DJ: Importance of early insulin levels on prandial glycaemic responses and thermogenesis in non-insulin-dependent diabetes mellitus. Diabet Med, 12, 1995: 523-530.
29. Olefsky JM: Prospects for research in diabetes mellitus. JAMA, 285, 2001: 628-632.
30. Pan X, Li G, Hu Y, Zuoxin A, Jixing W, Bennett PH, Howard BV:. Effect of dietary and/or exercise interventions on incidence of diabetes in 530 subjects with IGT The Da-Qing IGT and Diabetes Study. Proceedings 15th International Diabetes Federation Congress, Kobe, Japan, 1994: 489A.
31. Pickup JC, Williams G (Eds.): Textbook of Diabetes, Vol.2. Oxford-London, 1997.
32. Reaven GM, Laws A (Eds.): Insulin Resistance: the Metabolic Syndrome X. New York, 1999: 374 ff.
33. Ringelstein EB, Nabavi D: Long-term prevention of ischaemic stroke and stroke recurrence. Thromb Res, 98, 2000: 83-96.
34. Serrano-Rios M: Heterogenity diabetes mellitus 2. International Journal of Metabolism, 1, No. 25, 1997: 21.
35. Sinclair AJ: Diabetes mellitus. In: Pathy MSJ (Ed.): Principles and Practice of Geriatric Medicine, Vol. 2 - third edition, New York, 1998: 1321-1340
36. Sinclar AJ, Finucane P (Eds.): Diabetes in Old Age. Second Edition. New York, 2001: 274 ff.
37. The DCCT Research Group: The effect of intensive treatment of diabetes on development and progression long-term complications in insulin -dependent diabetes mellitus. N Engl J Med, 329, 1993: 977-986.
38. The DECODE Study Group: Glucose tolerance and mortality comparison of WHO and ADA diagnostic criteria. Lancet, 354, 1999: 617-621.
39. Tuomi T, Broop LC, Zimmet P, Rowley MJ, Knowles W, Mackay IR: Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin dependent onset of disease. Diabetes, 42, 1993: 359-362
40. Tuomilehto J, Zimmet P, Mackay IR, Koskela P, Vidgren G, Tolvanen L, Tuomilehto-Wolf E, Kohtamaki K, Stengard J, Rowley MJ: Antibodies to glutamic axid decarboxylase as predictors of insulin-dependent diabetes mellitus before the clinical onset of the disease. Lancet, 343, 1994: 1383-1385.
41. UKPDS, Turner RC, Cull C, Holman R: United Kingdom Prospective diabetes Study 17: A 9-year update of a randomized, controlled trial on the effect of improved metabolic control on complications in non-insulin-dependent diabetes mellitus Ann Intern Med, 124, 1 part. 2, 1996: 136-145.
42. UK Prospective Diabetes Study (UKPDS) Group: Intensive blood-glucose control with sulphonylurea or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. Lancet, 352, 1998: 837-853.
43. Zimmet P, Collier G: Clinical efficacy of metformin against insulin resistence parameters: Sinking the iceberg. Drugs, 58 Suppl 1, 1999: 21-28.
44. Zimmet P, Tuomi T, Mackay IR, Rowley MJ, Knowles W, Cohen M, Lang DA: Latent autoimmune diabetes mellitus in adtults (LADA)-the role of antibodies to glutaminic acid decarboxylase in diagnosis and prediction of insulin dependency. Diabetic Med, 11, 1994: 299-303.
45. Zimmet P: The pathogenesis and prevention of diabetes in adults: Genes, autoimmunity and demography. Diabetes Care, 18, 1995: 1050-1064.