IgG/IgA pemphigus with IgG and IgA antidesmoglein 1 antibodies detected by enzyme-linked immunosorbent assay

British Journal of Dermatology

Volumn 147, Issue 5, 2002, Pages 1012-1017

  Oiso, N ^a,e   Yamashita, C ^b   Yoshioka, K ^b   Amagai, M ^c   Komai, A ^d   Nagata, Y ^d   Hashimoto, T ^d   Ishii, M ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Izumi Municipal Hospital   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

Antikeratinocyte cell surface antibodies; Desmoglein 1; Enzyme linked immunosorbent assay; IgG IgA pemphigus

Indexed keywords

BETAMETHASONE VALERATE; DESMOGLEIN 1; DESMOGLEIN 3; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; MINOCYCLINE; PREDNISOLONE;

ADSORPTION; ADULT; ANIMAL CELL; ANTIBODY DETECTION; ANTIGEN ANTIBODY REACTION; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CASE REPORT; CLINICAL EXAMINATION; CLINICAL FEATURE; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOFLUORESCENCE; IN VIVO STUDY; NONHUMAN; PEMPHIGUS; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADULT; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; CADHERINS; DESMOGLEIN 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; PEMPHIGUS;

EID: 0036440664     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2002.04984.x     Document Type: Article

References (27)

1. Robinson ND, Hashimoto T, Amagai M et al. The new pemphigus variants. J Am Acad Dermatol 1999; 40: 649-71.
2. Amagai M. Autoimmunity against desmosomal cadherins in pemphigus. J Dermatol Sci 1999; 20: 92-102.
3. Santi CG, Maruta CW, Aoki V et al. Pemphigus herpetiformis is a rare clinical expression of nonendemic pemphigus foliaceus, fogo selvagem, and pemphigus vulgaris. J Am Acad Dermatol 1996; 34: 40-6.
4. Ishii K, Amagai M, Komai A et al. Desmoglein 1 and desmoglein 3 are the target autoantigens in herpetiform pemphigus. Arch Dermatol 1999; 135: 943-7.
5. Wallach D, Foldes C, Cattenot F. Pustulose sous-cornée acantholyse superficielle et IgA monoclonale. Ann Dermatol Venereol 1982; 109: 959-63.
6. Hashimoto T, Kiyokawa C, Mori O et al. Human desmocollin 1 (Dsc1) is an autoantigen for subcorneal pustular dermatosis type of IgA pemphigus. J Invest Dermatol 1997; 109: 127-31.
7. Ebihara T, Hashimoto T, Iwatsuki K et al. Autoantigens for IgA anti-intercellular antibodies of intercellular IgA vesiculopustular dermatosis. J Invest Dermatol 1991; 97: 42-5.
8. Beutner EH, Chorzelski TP, Wilson RM et al. IgA pemphigus foliaceus: Report of two cases and a review of literature. J Am Acad Dermatol 1989; 20: 89-97.
9. Hashimoto T, Ebihara T, Nishikawa T. Studies of autoantigens recognized by IgA anti-keratinocyte cell surface antibodies. J Dermatol Sci 1996; 12: 10-17.
10. Prost C, Intrator L, Wechsler J et al. IgA autoantibodies bind to pemphigus vulgaris antigen in a case of intraepidermal neutro-philic IgA dermatosis. J Am Acad Dermatol 1991; 25: 846-8.
11. Wang J, Kwon J, Ding X et al. Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis. Am J Pathol 1997; 150: 1901-7.
12. Karpati S, Amagai M, Liu WL et al. Identification of desmoglein 1 as an autoantigen in a patient with intraepidermal neutrophilic IgA dermatosis type of IgA pemphigus. Exp Dermatol 2000; 9: 224-8.
13. Hashimoto T, Komai A, Futei Y et al. An enzyme-linked immu-nosorbent assay detected IgA autoantibodies to desmogleins, suggesting the presence of new minor subtypes of IgA pemphigus. Arch Dermatol 2001; 137: 735-8.
14. Hashimoto T. Immunopathology in IgA pemphigus. Clin Dermatol 2001; 19: 683-9.
15. Ishii K, Amagai M, Hall RP et al. Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins. J Immunol 1997; 159: 2010-17.
16. Amagai M, Hashimoto T, Komai A et al. Usefulness of enzyme-linked immunosorbent assay (ELISA) using recombinant desm-ogleins 1 and 3 for serodiagnosis of pemphigus. Br J Dermatol 1999; 140: 351-7.
17. Harman KE, Gratian MJ, Seed PT et al. Diagnosis of pemphigus by ELISA: A critical evaluation of two ELISAs for the detection of antibodies to the major pemphigus antigens, desmoglein 1 and 3. Clin Exp Dermatol 2000; 25: 236-40.
18. Ishii K, Amagai M, Ohata Y et al. Development of pemphigus vulgaris in a patient with pemphigus foliaceus: Antidesmoglein antibody profile shift confirmed by enzyme-linked immunosorbent assay. J Am Acad Dermatol 2000; 42: 859-61.
19. Harman KE, Seed PT, Gratian MJ et al. The severity of cutaneous and oral pemphigus is related to desmoglein 1 and 3 antibody levels. Br J Dermatol 2001; 144: 775-80.
20. Chorzelski TP, Hashimoto T, Nishikawa T et al. Unusual acantholytic bullous dermatosis associated with neoplasia and IgG and IgA antibodies against bovine desmocollins I and II. J Am Acad Dermatol 1994; 31: 351-5.
21. Miyagawa S, Hashimoto T, Ohno H et al. Atypical pemphigus associated with monoclonal IgA gammopathy. J Am Acad Der-matol 1995; 32: 352-7.
22. Gooptu C, Mendelsohn S, Amagai M et al. Unique immunobullous disease in a child with a predominantly IgA response to three desmosomal proteins. Br J Dermatol 1999; 141: 882-6.
23. Hashimoto T, Ogawa MM, Konohana A et al. Detection of pemphigus vulgaris and pemphigus foliaceus antigens by immunoblot analysis using different antigen sources. J Invest Dermatol 1990; 94: 327-31.
24. Amagai M, Hashimoto T, Shimizu T et al. Adsorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus. J Clin Invest 1994; 94: 59-67.
25. Amagai M, Hashimoto T, Green K et al. Antigen-specific immunoadsorption of pathogenic autoantibodies in pemphigus foliac-eus. J Invest Dermatol 1995; 104: 895-901.
26. Spaeth S, Riechers R, Borradori L et al. IgG, IgA and IgE autoantibodies against the ectodomain of desmoglein 3 in active pemphigus vulgaris. Br J Dermatol 2001; 144: 1183-8.
27. Gregersen H, Mellemkjaer L, Salling Ibsen J et al. Cancer risk in patients with monoclonal gammopathy of undetermined significance. Am J Hematol 2000; 63: 1-6.