Limits of cooperativity in a structurally modular protein: Response of the Notch ankyrin domain to analogous alanine substitutions in each repeat

Journal of Molecular Biology

Volumn 324, Issue 2, 2002, Pages 373-386

  Bradley, Christina Marchetti ^a   Barrick, Doug ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Ankyrin repeat; Cooperativity; Notch signaling; Protein folding; Stability

Indexed keywords

ALANINE; ANKYRIN; GLYCINE; NOTCH RECEPTOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CALORIMETRY; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; DROSOPHILA MELANOGASTER; ENTHALPY; ENTROPY; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

DROSOPHILA MELANOGASTER;

EID: 0036438808     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00945-2     Document Type: Article

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