Preventive effects of parathyroid hormone-related peptide on stress-induced gastric hypercontraction in the rat

Journal of Gastroenterology and Hepatology (Australia)

Volumn 17, Issue 12, 2002, Pages 1260-1266

  Ito, Masahiro ^a   Nakashima, Masahiro ^b   Nakayama, Toshiyuki ^b   Shikuwa, Saburo ^a   Ohtsuru, Akira ^b   Sekine, Ichiro ^b  

^a NATIONAL HOSPITAL ORGANIZATION NAGASAKI MEDICAL CENTER   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Gastric motility; Parathyroid hormone related peptide; Parathyroid hormone parathyroid hormone related peptide receptor; Stress

Indexed keywords

MESSENGER RNA; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PEPTIDE[1-34]; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RIBONUCLEASE PROTECTION ASSAY; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE RELAXATION; STOMACH MOTILITY; STRAIN GAUGE TRANSDUCER; STRESS; WATER IMMERSION;

EID: 0036435554     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2002.02883.x     Document Type: Article

References (24)

1. Suva L, Winslow GA, Wettenhall REH et al. A parathyroid hormone-related protein implicated malignant hypercalcemia. Science 1987; 237: 893-6.
2. Mangin M, Ikeda K, Dreyer BE et al. Isolation and characterization of the human parathyroid hormone-like peptide gene. Proc. Natl Acad. Sci. USA 1989; 86: 2408-12.
3. Philbrick WM, Wysolmerski JJ, Galbraith S et al. Defining the role of parathyroid hormone-related protein in normal physiology. Physiol. Rev. 1996; 76: 127-73.
4. Ikeda K, Weir EC, Mangin N et al. Expression of messenger ribonucleic acids encoding a parathyroid hormone-like peptide in normal human and animal tissues with abnormal expression in human parathyroid adenomas. Mol. Endocrinol. 1988; 2: 1230-6.
5. Moseley JM, Hayman JA, Danks JA et al. Immunohistochemical detection of parathyroid hormone-related protein in human fetal epithelia. J. Clin. Endocrinol. Metab. 1991; 73: 478-84.
6. Ito M, Ohtsuru A, Enomoto H et al. Expression of parathyroid hormone-related peptide in perturbation of rat gastric motility. Endocrinology 1994; 134: 1936-42.
7. Cooper CW, Seitz PK, McPherson MB et al. Effects of parathyroid hormonal peptides on the gut. Contrib. Nephrol. 1991; 91: 26-31.
8. Abou-Samra AB, Juppner H, Force T et al. Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol triphosphates and increases intracellular free calcium. Proc. Natl Acad. Sci. USA 1992; 89: 2732-6.
9. Daifotis AG, Weir EC, Dreyer BE et al. Stretch-induced parathyroid hormone-related peptide gene expression in the rat uterus. J. Biol. Chem. 1992; 267: 23455-8.
10. Thiede MA, Harm SC, McKee RL et al. Expression of the parathyroid hormone-related protein gene in the avian oviduct: Potential role as a local modulator of vascular smooth muscle tension and shell gland motility during the egg-laying cycle. Endocrinology 1991; 129: 1958-66.
11. Thiede MA, Weir AGEC, Brines ML et al. Intrauterine occupancy controls expression of the parathyroid hormone-related peptide gene in preterm rat myometrium. Proc. Natl Acad. Sci. USA 1990; 87: 6969-73.
12. Yamamoto M, Harm SC, Grasser WA et al. Parathyroid hormone-related protein in the rat urinary bladder: A smooth muscle relaxant produced locally in response to mechanical stretch. Proc. Natl Acad. Sci. USA 1992; 89: 5326-30.
13. Ito M, Shichijo K, Sekine I. Gastric motility and ischemic changes in occurrence of linear ulcer formation induced by restraint-water immersion stress in rat. Gastroenterol. Jpn. 1993; 28: 367-73.
14. Takagi K, Okabe S. The effects of the production and recovery processes of the stress ulcer. Jpn. J. Pharmacol. 1968; 18: 9-18.
15. Ozeki S, Ohtsuru A, Seto Set al. Evidence that implicates the parathyroid hormone-related peptide in vascular stenosis. Increased gene expression in the intima of injured carotid arteries and human restenotic coronary lesions. Arterioscler. Thromb. Vasc. Biol. 1996; 16: 565-75.
16. Hongo T, Kupfer J, Enomoto Het al. Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation. J. Clin. Invest. 1991; 88: 1841-7.
17. Pirola CJ, Wang H, Kamyar A et al. Angiotensin II regulation parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and posttranscriptional mechanisms. J. Biol. Chem. 1993; 25: 1987-94.
18. Urena P, Kong XF, Abou-Samra AB et al. Parathyroid hormone (PTH)/PTHrP-related peptide receptor messenger ribonucleic acid are widely distributed in rat tissues. Endocrinology 1993; 133: 617-23.
19. Urena P, Iida-Klein A, Kong XF et al. Regulation of parathyroid hormone (PTH)/PTHrP-related peptide receptor messenger ribonucleic acid by glucocorticoids and PTH in ROS 17/2.8 OK cells. Endocrinology 1994; 134: 451-6.
20. Mok LLS, Ajiwa E, Martin J et al. Parathyroid hormone-related protein relaxes rat gastric smooth muscle and shows cross-desensitization with parathyroid hormone. J. Bone Miner. Res. 1989; 4: 433-9.
21. Botella AM, Rekik M, Delvaux M et al. Parathyroid hormone and PTH-related protein relaxes rat gastric smooth muscle cells from guinea pig ileum: Interaction with vaso-active intestinal peptide receptors. Endocrinology 1994; 135: 2160-7.
22. Mok LL, Cooper CW, Thompson JC. Parathyroid hormone and parathyroid hormone-related protein inhibit phasic contraction of pig duodenal smooth muscle. Proc. Soc. Exp. Biol. Med. 1989; 191: 337-40.
23. Shenberger JS, Shew RL, Johnson DE et al. Relaxation of porcine tracheal smooth muscle by parathyroid hormone-related protein. Respir. Physiol. 1997; 107: 59-66.
24. Care AD, Abbas SK, Harmeyer J et al. The relaxant effects of parathyroid hormone (1-34) and parathyroid hormone-related protein (1-34) on ovine reticuloruminal smooth muscle in vivo. Exp. Physiol. 1999; 84: 665-75.