Recombinant adenovirus encoding H-ras ribozyme induces apoptosis in laryngeal cancer cells through caspase- and mitochondria-dependent pathways

Biochemical and Biophysical Research Communications

Volumn 298, Issue 5, 2002, Pages 805-814

  Wang, Chih Hung ^a,b   Tsai, Li Jen ^a   Tsao, Yeou Ping ^c   Hsieh, Jer Tsong ^d   Chien, Wei Wen ^a   Liao, Ching Len ^a   Wang, Hsing Won ^b   Liu, Hsiao Sheng ^e   Chen, Show Li ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Caspase; H ras; Mitochondria

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; RIBOZYME;

ADENOVIRUS; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CODON; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; LARYNX CANCER; MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL; PROTEIN SECRETION; VIRUS RECOMBINANT; WILD TYPE;

ADENOVIRIDAE; APOPTOSIS; CASPASES; CELL DIVISION; CYTOCHROME C GROUP; ENZYME ACTIVATION; GENE THERAPY; GENES, BCL-2; GENES, RAS; HUMANS; LARYNGEAL NEOPLASMS; MITOCHONDRIA; RNA, CATALYTIC; TUMOR CELLS, CULTURED;

ADENOVIRIDAE;

EID: 0036432830     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02574-3     Document Type: Article

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