BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro. Implications in the BIGH3-linked corneal dystrophies

European Journal of Biochemistry

Volumn 269, Issue 21, 2002, Pages 5149-5156

  Schmitt Bernard, Clair Florent ^a,b   Chavanieu, Alain ^c   Herrada, Gudrun ^c   Subra, Guy ^c   Arnaud, Bernard ^d   Demaille, Jacques G ^a   Calas, Bernard ^c   Argilés, Ángel ^a  

^a INSTITUTE OF HUMAN GENETICS   (France)

^b Antigone Ophtalmologie   (France)

^c UNIV MONTPELLIER   (France)

^d GUI DE CHAULIAC HOSPITAL   (France)

Author keywords

Amyloidosis; Granular corneal dystrophy; Keratoepithelin; Lattice corneal dystrophy; Synthetic peptide

Indexed keywords

AMYLOID; ARGININE; CYSTEINE; DISULFIDE; HISTIDINE; MUTANT PROTEIN; PEPTIDE; TRANSFORMING GROWTH FACTOR BETA; VALINE;

AMINO ACID SEQUENCE; AMYLOIDOSIS; ARTICLE; BETA SHEET; CODON; CONGENITAL CORNEA DYSTROPHY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; INFRARED SPECTROSCOPY; MOLECULAR DYNAMICS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN FUNCTION; TERMINAL SEQUENCE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMYLOID; CORNEAL DYSTROPHIES, HEREDITARY; DEUTERIUM OXIDE; EXTRACELLULAR MATRIX PROTEINS; FLUORESCENT DYES; HYDROGEN BONDING; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOPLASM PROTEINS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; SEQUENCE DELETION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TRANSFORMING GROWTH FACTOR BETA;

EID: 0036431646     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.03205.x     Document Type: Article

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