Endothelium-dependent vasodilation in normotensive subjects with a familial history of essential hypertension and in young subjects with borderline hypertension

Blood Pressure

Volumn 11, Issue 5, 2002, Pages 279-284

  Millgard, Jonas ^a   Hägg, Anders ^a   Sarabi, Mahziar ^a   Lind, Lars ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Blood pressure; Borderline hypertension; Endothelium; Heredity; Hypertension; Vasodilation

Indexed keywords

METHACHOLINE; NITROPRUSSIDE SODIUM;

ADULT; ARTICLE; BLOOD PRESSURE; BORDERLINE HYPERTENSION; CALCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM INJURY; ESSENTIAL HYPERTENSION; FAMILY HISTORY; FOREARM BLOOD FLOW; HUMAN; MALE; MEDICAL ASSESSMENT; PATHOGENESIS; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; VASODILATATION; VEIN OCCLUSION PLETHYSMOGRAPHY;

ADULT; ENDOTHELIUM, VASCULAR; FEMALE; FOREARM; HUMANS; HYPERTENSION; MALE; MEDICAL RECORDS; METHACHOLINE CHLORIDE; NITROPRUSSIDE; PLETHYSMOGRAPHY; REFERENCE VALUES; REGIONAL BLOOD FLOW; SEVERITY OF ILLNESS INDEX; VASODILATION; VASODILATOR AGENTS;

EID: 0036429238     PISSN: 08037051     EISSN: None     Source Type: Journal    
DOI: 10.1080/080370502320779485     Document Type: Article

References (17)

1. Lüscher TF, Vanhoutte PM. The endothelium: modulator of cardiovascular function. Boca Raton: CRP Press, 1990.
2. Lüscher TF. The endothelium in cardiovascular disease. Berlin: Springer-Verlag, 1995.
3. Furchgott RF, Zawadski JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 299: 373-6.
4. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524-6.
5. De Caterina R, Libby P, Peng HB, et al. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 1995; 96: 60-8.
6. Yangisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411-15.
7. Boulanger C, Lüscher TF. Release of endothelin from the porcine aorta. Inhibition of endothelium-derived nitric oxide. J Clin Invest 1990; 85: 587-90.
8. Hirata Y, Takagi Y, Fukuda Y, Marumo F. Endothelin is a potent mitogen for rat vascular smooth muscle cells. Atherosclerosis 1989; 78: 225-8.
9. Panza JA, Quyyumi AA, Brush Jr JE, Epstein SE. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990; 323: 22-7.
10. Hirooka Y, Imaizumi T, Masaki H, et al. Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients. Hypertension 1992; 20: 175-80.
11. Creager MA, Roddy M-A, Coleman SM, Dzau VJ. The effect of ACE inhibition on endothelium-dependent vasodilation in hypertension. J Vasc Res 1992; 29: 97-8.
12. Taddei S, Virdis A, Mattei P, Salvetti A. Vasodilation to acetylcholine in primary and secondary forms of hypertension. Hypertension 1993: 21: 929-33.
13. Taddei S, Virdis A, Mattei P, Arzilli F, Salvetti A. Endothelium-dependent forearm vasodilation is reduced in normotensive subjects with familial history of hypertension. J Cardiovasc Pharmacol 1992; 20 Suppl 12: S193-5.
14. Lemne C. Borderline hypertension-a case-control study of atherosclerotic risk factors and early cardiovascular adaptation. Thesis, Karolinska Hospital and Karolinska Institute, Stockholm, Sweden, 1994.
15. Lind L, Sarabi M, Millgård J. Methodological aspects of the evaluation of endothelium-dependent vasodilation in the human forearm. Clin Physiol 1998; 18: 81-7.
16. Taddei S, Virdis A, Mattei P, Ghiadoni L, Sudano I, Salvetti A. Defective L-arginine-nitric oxide pathway in offspring of essential hypertensive patients. Circulation 1996; 94: 1298-303.
17. Wall U, Jern C, Bergbrant A, Jern S. Enhanced levels of tissue-type plasminogen activator in borderline hypertension. Hypertension 1995; 26: 796-800.