Eotaxin induces migration of RBL-2H3 mast cells via a Rac-ERK-dependent pathway

Biochemical and Biophysical Research Communications

Volumn 298, Issue 3, 2002, Pages 392-397

  Woo, Chang Hoon ^a   Tak Jeong, Dong ^b   Yoon, Seog Beom ^b   Kim, Key Sun ^c   Yup Chung, Il ^d   Saeki, Toshihiko ^e   Kim, Jae Hong ^a  

^a Korea University   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

^d Hanyang University   (South Korea)

^e BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Chemotaxis; Eotaxin; ERK; Rac; RBL 2H3

Indexed keywords

ACTIN; CHEMOKINE RECEPTOR CCR3; EOTAXIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MUTANT PROTEIN; RAC PROTEIN;

ANIMAL CELL; ARTICLE; BASOPHIL; CELL LINE; CELL MIGRATION; CELL MOTILITY; CHEMOTAXIS; CONTROLLED STUDY; DOSE RESPONSE; EOSINOPHIL; LEUKEMIA CELL; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CHEMOKINES, CC; CHEMOTAXIS; DNA PRIMERS; MAST CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C; RAC GTP-BINDING PROTEINS; RATS; TUMOR CELLS, CULTURED;

EID: 0036429016     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02432-4     Document Type: Article

References (30)

1. M. Baggiolini, B. Bewald, B. Moser, Human chemokines: An update, Ann. Rev. Immunol. 15 (1997) 675-705.
2. M.E. Rothenberg, Eotaxin - An essential mediator of eosinophils trafficking into mucosal tissues, Am. J. Respir. Cell Mol. Biol. 21 (1999) 291-295.
3. J.-L. Gao, A.I. Sen, M. Kitaura, O. Yoshie, M.E. Rothenberg, P.M. Murphy, A.D. Luster, Identification of a mouse eosinophil receptor for the CC chemokine eotaxin, Biochem. Biophys. Res. Commun. 223 (1996) 679-684.
4. S.J. Han, J.H. Kim, Y.J. Noh, H.S. Chang, C.S. Kim, K.S. Kim, S.Y. Ki, C.S. Park, I.Y. Chung, Interleukin (IL)-5 downregulates tumor necrosis factor (TNF)-induced eotaxin messenger RNA (mRNA) expression in eosinophils. Induction of eotaxin mRNA by TNF and IL-5 in eosinophils, Am. J. Respir. Cell Mol. Biol. 21 (1999) 303-310.
5. T. Saeki, K. Ohwaki, A. Naya, K. Kobayashi, M. Ishikawa, N. Ohtake, K. Noguchi, Identification of a potent and nonpeptidyl ccr3 antagonist, Biochem. Biophy. Res. Commun. 281 (2001) 779-782.
6. J.A. Gonzalo, C.M. Lloyd, L. Kremer, E. Finger, A.C. Martinez, M.H. Siegelman, M. Cybulsky, J.C. Gutierrezramos, Eosinophil recruitment to the lung in a murine model of allergic inflammation: The role of T cells, chemokine, and adhesion receptors, J. Clin. Invest. 98 (1996) 2332-2345.
7. A.J. Wardlaw, R.M. Moqbel, A.B. Kay, Eosinophils and the allergic inflammatory response, in: A.B. Kay (Ed.), Allergy and Allergic Diseases, Blackwell Science Ltd., Massachusetts, pp. 171-197.
8. B.L. Daugherty, S.J. Siciliano, J.A. DeMartino, L. Malkowitz, A. Sirotina, M.S. Springer, Cloning, expression, and characterization of the human eosinophil eotaxin receptor, J. Exp. Med. 183 (1996) 2349-2354.
9. M. Kitaura, T. Nakaijima, T. Imai, Molecular cloning of human eotaxin an eosinophil-selective CC chemokine and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3, J. Biol. Chem. 271 (1996) 7725-7730.
10. P.D. Ponath, S. Qin, T.W. Post, Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils, J. Exp. Med. 1839 (1996) 2437-2448.
11. G.T. Kampen, S. Stafford, T. Adachi, T. Jinquan, S. Quan, J.A. Grant, P.S. Skov, L.K. Poulsen, R. Alam, Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases, Blood 95 (2000) 1911-1917.
12. H. Yamada, K. Hirai, M. Miyamasu, M. Iikura, Y. Misaki, S. Shoji, T. Takaishi, T. Kasahara, Y. Morita, K. Ito, Eotaxin is a potent chemotaxis for human basophils, Biochem. Biophys. Res. Commun. 231 (1997) 365-368.
13. M. Iikura, M. Miyamasu, M. Yamaguchi, H. Kawasaki, K. Matsushima, M. Kitaura, Y. Morita, O. Yoshie, K. Yamamoto, K. Hirai, Chemokine receptors in human basophils: Inducible expression of functional CXCR4, J. Leukoc. Biol. 70 (2001) 113-120.
14. A. De Paulis, F. Annunziato, L. Di Gioia, S. Romagnani, M. Carfora, C. Beltrame, G. Marone, P. Romagnani, Expression of the chemokine receptor CCR3 on human mast cells, Int. Arch. Allergy Immunol. 124 (2001) 146-150.
15. F. Sallusto, C.R. Mackay, A. Lanzavecchia, Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells, Science 277 (1997) 2005-2007.
16. C.H. Woo, H.J. You, S.H. Cho, Y.W. Eom, J.S. Chun, Y.J. Yoo, J.H. Kim, Leukotriene B(4) stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis, J. Biol. Chem. 277 (2002) 8572-8578.
17. L.V. Aelst, C. D'Souza-Schorey, Rho GTPases and signaling networks, Genes Dev. 11 (1997) 2295-2322.
18. P.J. Keely, J.K. Westwick, I.P. Whitehead, C.J. Der, L.V. Parise, Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K, Nature 390 (1997) 632-636.
19. J.V. Small, T. Stradal, E. Vignal, K. Rottner, The lamellipodium: Where motility begins, Trends Cell Biol. 12 (2002) 112-120.
20. B.C. Kim, Y.J. Yi, S.J. Yi, I.C. Shin, K.S. Ha, B.H. Jhun, S.B. Hwang, J.H. Kim, Rac GTPase activity is essential for EGF-induced mitogenesis in Rat-2 fibroblasts cells, Mol. Cells 8 (1998) 90-95.
21. J.H. Kim, F.E. Johansen, N. Robertson, J.J. Catino, R. Prywes, C.C. Kumar, Suppression of Ras transformation by serum response factor, J. Biol. Chem. 269 (1994) 13740-13743.
22. T. Akasaki, H. Koga, H. Sumimoto, Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils, J. Biol. Chem. 274 (1999) 18055-18059.
23. K.S. Ha, J.H. Exton, Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts, J. Cell Biol. 123 (1993) 1789-1796.
24. R. Perona, S. Montaner, L. Saniger, I. Sanchez-Perez, R. Bravo, J.C. Lacal, Activation of the nuclear factor-κB by Rho, CDC42, and Rac-1 proteins, Genes Dev. 11 (1997) 463-475.
25. C.H. Woo, Y.W. Eom, M.H. Yoo, H.J. You, H.J. Han, W.K. Song, Y.J. Yoo, J.S. Chun, J.H. Kim, Tumor necrosis factor-α generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade, J. Biol. Chem. 275 (2000) 32357-32362.
26. J.C. Guillemot, P. Montcourrier, E. Vivier, J. Davoust, P. Chavrier, Selective control of membrane ruTing and actin plaque assembly by the Rho GTPases Rac1 and CDC42 in Fcε RI-activated rat basophilic leukemia (RBL-2H3) cells, J. Cell Sci. 110 (1997) 2215-2225.
27. S.A. Boehme, S.K. Sullivan, P.D. Crowe, M. Santos, P.J. Conlon, P. Sriramarao, K.B. Bacon, Activation of mitogen-activated protein kinase regulates eotaxin-induced eosinophil migration, J. Immunol. 163 (1999) 1611-1618.
28. Q. Lu, M. Paredes, J. Zhang, K.S. Kosik, Basal extracellular signal-regulated kinase activity modulates cell-cell and cell-matrix interactions, Mol. Cell Biol. 18 (1998) 3257-3265.
29. A.A. Reszka, J.C. Bulinski, E.G. Krebs, E.H. Fischer, Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions, Mol. Biol. Cell 8 (1997) 1219-1232.
30. J.C. Hedges, B.C. Oxhorn, M. Carty, L.P. Adam, I.A. Yamboliev, W.T. Gerthoffer, Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle, Am. J. Physiol. Cell Physiol. 278 (2000) C718-C726.