메뉴 건너뛰기




Volumn 46, Issue 2, 2002, Pages 545-556

Glutathione regulates the expression of γ-glutamylcysteine synthetase via the Met4 transcription factor

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; METHIONINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MET4; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

EID: 0036428692     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.03174.x     Document Type: Article
Times cited : (33)

References (39)
  • 1
    • 0028859433 scopus 로고
    • Characterization of a dominant negative mutant of the cell cycle ubiquitin-conjugating enzyme Cdc34
    • Banerjee, A., Deshaies, R.J., and Chau, V. (1995) Characterization of a dominant negative mutant of the cell cycle ubiquitin-conjugating enzyme Cdc34. J Biol Chem 270: 26209-26215.
    • (1995) J Biol Chem , vol.270 , pp. 26209-26215
    • Banerjee, A.1    Deshaies, R.J.2    Chau, V.3
  • 3
    • 0032488513 scopus 로고    scopus 로고
    • Recent trends in glutathione biochemistry-glutathione-protein interactions: A molecular link between oxidative stress and cell proliferation?
    • Cotgreave, I.A., and Gerdes, R.G. (1998) Recent trends in glutathione biochemistry-glutathione-protein interactions: A molecular link between oxidative stress and cell proliferation? Biochem Biophys Res Com 242: 1-9.
    • (1998) Biochem Biophys Res Com , vol.242 , pp. 1-9
    • Cotgreave, I.A.1    Gerdes, R.G.2
  • 4
    • 0034597012 scopus 로고    scopus 로고
    • H2O2 sensing through oxidation of the Yap1 transcription factor
    • Delaunay, A., Isnard, A.-D., and Toledano, M.B. (2000) H2O2 sensing through oxidation of the Yap1 transcription factor. EMBO J 19: 5157-5166.
    • (2000) EMBO J , vol.19 , pp. 5157-5166
    • Delaunay, A.1    Isnard, A.-D.2    Toledano, M.B.3
  • 5
    • 0034693270 scopus 로고    scopus 로고
    • Cadmium inducible expression of the yeastGSH1 gene requires a functional sulphur-amino acid regulatory network
    • Dormer, U.H., sWestwater, J., McLaren, N.F., Kent, N.A., Mellor, J., and Jamieson, D.J. (2000) Cadmium inducible expression of the yeast GSH1 gene requires a functional sulphur-amino acid regulatory network. J Biol Chem 275: 32611-32616.
    • (2000) J Biol Chem , vol.275 , pp. 32611-32616
    • Dormer, U.H.1    Swestwater, J.2    McLaren, N.F.3    Kent, N.A.4    Mellor, J.5    Jamieson, D.J.6
  • 6
    • 0031888539 scopus 로고    scopus 로고
    • Toxicity of linoleic acid hydroperoxide to Saccharomyces cerevisiae: Involvement of a respiration-related process for maximal sensitivity and adaptive response
    • Evans, M.V., Turton, H.E., Grant, C.M., and Dawes, I.W. (1997) Toxicity of linoleic acid hydroperoxide to Saccharomyces cerevisiae: Involvement of a respiration-related process for maximal sensitivity and adaptive response. J Bacteriol 180: 483-490.
    • (1997) J Bacteriol , vol.180 , pp. 483-490
    • Evans, M.V.1    Turton, H.E.2    Grant, C.M.3    Dawes, I.W.4
  • 7
    • 0026562884 scopus 로고
    • Improved method for high efficiency transformation of intact yeast cells
    • Geitz, D., St. Jean, A., Woods, R.A., and Schiestl, R.H. (1992) Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res 20: 1425.
    • (1992) Nucleic Acids Res , vol.20 , pp. 1425
    • Geitz, D.1    St. Jean, A.2    Woods, R.A.3    Schiestl, R.H.4
  • 8
    • 0030004354 scopus 로고    scopus 로고
    • Glutathione is an essential metabolite required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae
    • Grant, C.M., MacIver, F.H., and Dawes, I.W. (1996a) Glutathione is an essential metabolite required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae. Curr Genet 29: 511-515.
    • (1996) Curr Genet , vol.29 , pp. 511-515
    • Grant, C.M.1    MacIver, F.H.2    Dawes, I.W.3
  • 9
    • 0030016469 scopus 로고    scopus 로고
    • Yeast glutathione reductase is required for protection against oxidative stress and is a target gene for yAP-1 transcriptional regulation
    • Grant, C.M., Collinson, L.P., Roe, J.-H., and Dawes, I.W. (1996b) Yeast glutathione reductase is required for protection against oxidative stress and is a target gene for yAP-1 transcriptional regulation. Mol Microbiol 21: 171-179.
    • (1996) Mol Microbiol , vol.21 , pp. 171-179
    • Grant, C.M.1    Collinson, L.P.2    Roe, J.-H.3    Dawes, I.W.4
  • 10
    • 0029834918 scopus 로고    scopus 로고
    • Stationary phase induction of GLR1 expression is mediated by the yAP-1 transcriptional protein in Saccharomyces cerevisiae
    • Grant, C.M., MacIver, F.M., and Dawes, I.W. (1996c) Stationary phase induction of GLR1 expression is mediated by the yAP-1 transcriptional protein in Saccharomyces cerevisiae. Mol Microbiol 22: 739-746.
    • (1996) Mol Microbiol , vol.22 , pp. 739-746
    • Grant, C.M.1    MacIver, F.M.2    Dawes, I.W.3
  • 11
    • 0030747207 scopus 로고    scopus 로고
    • Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine
    • Grant, C.M., MacIver, F.H., and Dawes, I.W. (1997) Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine. Mol Biol Cell 8: 1699-1707.
    • (1997) Mol Biol Cell , vol.8 , pp. 1699-1707
    • Grant, C.M.1    MacIver, F.H.2    Dawes, I.W.3
  • 12
    • 0032956855 scopus 로고    scopus 로고
    • Differential protein S-thiolation of Glyceraldhyde 3-phosphate dehydrogenase isoenzymes influences sensitivity to oxidative stress
    • Grant, C.M., Quinn, K.A., and Dawes, I.W. (1999) Differential protein S-thiolation of Glyceraldhyde 3-phosphate dehydrogenase isoenzymes influences sensitivity to oxidative stress. Mol Cell Biol 19: 2650-2656.
    • (1999) Mol Cell Biol , vol.19 , pp. 2650-2656
    • Grant, C.M.1    Quinn, K.A.2    Dawes, I.W.3
  • 13
    • 0033794872 scopus 로고    scopus 로고
    • Cysteine is essential for transcriptional regulation of the sulphur assimilation genes in Saccharomyces cerevisiae
    • Hansen, J., and Johannesen, P.F. (2000) Cysteine is essential for transcriptional regulation of the sulphur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet 263: 535-542.
    • (2000) Mol Gen Genet , vol.263 , pp. 535-542
    • Hansen, J.1    Johannesen, P.F.2
  • 14
    • 0028935165 scopus 로고
    • Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
    • Hochstrasser, M. (1995) Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr Opin Cell Biol 7: 215-223.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 215-223
    • Hochstrasser, M.1
  • 15
    • 0032506937 scopus 로고    scopus 로고
    • Molecular identification of glutathione synthetase (GSH2) gene from Saccharomyces cerevisiae
    • Inoue, Y., Sugiyama, K.-I., Izawa, S., and Kimura, A. (1998) Molecular identification of glutathione synthetase (GSH2) gene from Saccharomyces cerevisiae. Biochem Biophys Acta 1395: 315-320.
    • (1998) Biochem Biophys Acta , vol.1395 , pp. 315-320
    • Inoue, Y.1    Sugiyama, K.-I.2    Izawa, S.3    Kimura, A.4
  • 16
    • 0029042565 scopus 로고
    • Oxidative stress in yeast: Effect of glutathione on adaption to hydrogen peroxide stress in Saccharomyces cerevisiae
    • Izawa, S., Inoue, Y., and Kimura, A. (1995) Oxidative stress in yeast: Effect of glutathione on adaption to hydrogen peroxide stress in Saccharomyces cerevisiae. FEBS Lett 368: 73-76.
    • (1995) FEBS Lett , vol.368 , pp. 73-76
    • Izawa, S.1    Inoue, Y.2    Kimura, A.3
  • 17
    • 0034604341 scopus 로고    scopus 로고
    • Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF (Met30) -mediated inactivation of the transcription factor Met4
    • Kaiser, P., Flick, K., Wittenberg, C., and Reed, S.I. (2000) Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF (Met30) -mediated inactivation of the transcription factor Met4. Cell 102: 303-314.
    • (2000) Cell , vol.102 , pp. 303-314
    • Kaiser, P.1    Flick, K.2    Wittenberg, C.3    Reed, S.I.4
  • 18
    • 0028057226 scopus 로고
    • YAP1 dependent activation ofTRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides
    • Kuge, S., and Jones, N. (1994)YAP1 dependent activation ofTRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. EMBO J 13: 655-664.
    • (1994) EMBO J , vol.13 , pp. 655-664
    • Kuge, S.1    Jones, N.2
  • 19
    • 0033523113 scopus 로고    scopus 로고
    • Yap1 and Skn7 control two specialized oxidative stress response regulonsin yeast
    • Lee, J., Godon, C., Lagniel, G., Spector, D., Garin, J., Labarre, J., and Toledano, M.B. (1999) Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast. J Biol Chem 274: 16040-16046.
    • (1999) J Biol Chem , vol.274 , pp. 16040-16046
    • Lee, J.1    Godon, C.2    Lagniel, G.3    Spector, D.4    Garin, J.5    Labarre, J.6    Toledano, M.B.7
  • 20
    • 0035735334 scopus 로고    scopus 로고
    • The essential and ancillary role of glutathione in Saccharomyces cerevisiae: Studies with a grande gsh1 disruptant strain
    • Lee, J.-C., Straffon, M.J., Jang, T.-Y., Grant, C.M., and Dawes, I.W. (2001) The essential and ancillary role of glutathione in Saccharomyces cerevisiae: Studies with a grande gsh1 disruptant strain. FEMS Yeast Res 1: 57-65.
    • (2001) FEMS Yeast Res , vol.1 , pp. 57-65
    • Lee, J.-C.1    Straffon, M.J.2    Jang, T.-Y.3    Grant, C.M.4    Dawes, I.W.5
  • 21
    • 0031013876 scopus 로고    scopus 로고
    • A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis (glutathionato) cadmium
    • Li, Z.-S., Lu, Y.-P., Zhen, R.-G., Szczypka, M., Thiele, D.J., and Rea, P.A. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis (glutathionato) cadmium. Proc Natl Acad Sci USA 94: 42-47.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 42-47
    • Li, Z.-S.1    Lu, Y.-P.2    Zhen, R.-G.3    Szczypka, M.4    Thiele, D.J.5    Rea, P.A.6
  • 22
    • 0027174146 scopus 로고
    • A high copy number of yeast γ-glutamylcysteine synthetase suppresses a nuclear mutation affecting mitochondrial translation
    • Lisowsky, T. (1993) A high copy number of yeast γ-glutamylcysteine synthetase suppresses a nuclear mutation affecting mitochondrial translation. Curr Genet 23: 408-413.
    • (1993) Curr Genet , vol.23 , pp. 408-413
    • Lisowsky, T.1
  • 23
    • 0035504267 scopus 로고    scopus 로고
    • gamma-Glutamyl transpeptidase in the yeast Saccharomyces cerevisiae and its role in the vacuolar transport and metabolism of glutathione
    • Mehdi, K., Thierie, J., and Penninckx, M.J. (2001) gamma-Glutamyl transpeptidase in the yeastSaccharomyces cerevisiae and its role in the vacuolar transport and metabolism of glutathione. Biochem J 359: 631-637.
    • (2001) Biochem J , vol.359 , pp. 631-637
    • Mehdi, K.1    Thierie, J.2    Penninckx, M.J.3
  • 25
    • 0032796721 scopus 로고    scopus 로고
    • A new HPLC method for the simultaneous determination of oxidized and reduced plasma aminothiols using coulemetric electrochemical detection
    • Melnyk, S., Pogribny, I., Hine, R.J., and James, S.J. (1999) A new HPLC method for the simultaneous determination of oxidized and reduced plasma aminothiols using coulemetric electrochemical detection. J Nutr Biochem 10: 490-497.
    • (1999) J Nutr Biochem , vol.10 , pp. 490-497
    • Melnyk, S.1    Pogribny, I.2    Hine, R.J.3    James, S.J.4
  • 26
    • 0028961858 scopus 로고
    • Role of the Saccharomyces cerevisiae general regulatory factor CP1 in methionine biosynthetic gene transcription
    • O'Connell, K.F., Surdin-Kerjan, Y., and Baker, R.E. (1995) Role of the Saccharomyces cerevisiae general regulatory factor CP1 in methionine biosynthetic gene transcription. Mol Cell Biol 15: 1879-1888.
    • (1995) Mol Cell Biol , vol.15 , pp. 1879-1888
    • O'Connell, K.F.1    Surdin-Kerjan, Y.2    Baker, R.E.3
  • 27
    • 0034599725 scopus 로고    scopus 로고
    • SCF (Met30) -mediated control of the transcriptional activator Met4 is required for the G (1) -S transition
    • Patton, E., Peyraud, C., Rouillon, A., Surdin-Kerjan, Y., Tyers, M., and Thomas, D. (2000) SCF (Met30) -mediated control of the transcriptional activator Met4 is required for the G (1) -S transition. EMBO J 19: 1613-1624.
    • (2000) EMBO J , vol.19 , pp. 1613-1624
    • Patton, E.1    Peyraud, C.2    Rouillon, A.3    Surdin-Kerjan, Y.4    Tyers, M.5    Thomas, D.6
  • 28
    • 0020645053 scopus 로고
    • Construction and use of gene fusions to lacZ (β-galactosidase) which are expressed in yeast
    • Rose, M., and Botstein, D. (1983) Construction and use of gene fusions to lacZ (β-galactosidase) which are expressed in yeast. Meth Enzymol 101: 167-180.
    • (1983) Meth Enzymol , vol.101 , pp. 167-180
    • Rose, M.1    Botstein, D.2
  • 29
    • 0034677224 scopus 로고    scopus 로고
    • Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF (Met30) complex
    • Rouillon, A., Barbey, R., Patton, E.E., Tyers, M., and Thomas, D. (2000) Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF (Met30) complex. EMBO J 19: 282-294.
    • (2000) EMBO J , vol.19 , pp. 282-294
    • Rouillon, A.1    Barbey, R.2    Patton, E.E.3    Tyers, M.4    Thomas, D.5
  • 30
    • 0033895727 scopus 로고    scopus 로고
    • Structure-function analysis of yeast mRNA cap methyltransferase and high-copy suppression of conditional mutants by AdoMet synthase and the ubiquitin conjugating enzyme Cdc34p
    • Schwer, B., Saha, N., Mao, X., Chen, H.W., and Shuman, S. (2000) Structure-function analysis of yeast mRNA cap methyltransferase and high-copy suppression of conditional mutants by AdoMet synthase and the ubiquitin conjugating enzyme Cdc34p. Genetics 155: 1561-1576.
    • (2000) Genetics , vol.155 , pp. 1561-1576
    • Schwer, B.1    Saha, N.2    Mao, X.3    Chen, H.W.4    Shuman, S.5
  • 31
    • 0035831449 scopus 로고    scopus 로고
    • A genetic investigation of the essential role of glutathione: Mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast
    • Spector, D., Labarre, J., and Toledano, M.B. (2001) A genetic investigation of the essential role of glutathione: Mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast. J Biol Chem 276: 7011-7016.
    • (2001) J Biol Chem , vol.276 , pp. 7011-7016
    • Spector, D.1    Labarre, J.2    Toledano, M.B.3
  • 32
    • 0030222083 scopus 로고    scopus 로고
    • Glutathione is an important antioxidant molecule in the yeast Saccharomyces cerevisiae
    • Stephen, D.W.S., and Jamieson, D.J. (1996) Glutathione is an important antioxidant molecule in the yeastSaccharomyces cerevisiae. FEMS Lett 141: 207-212.
    • (1996) FEMS Lett , vol.141 , pp. 207-212
    • Stephen, D.W.S.1    Jamieson, D.J.2
  • 33
    • 0031034766 scopus 로고    scopus 로고
    • Amino acid-dependent regulation of the Saccharomyces cerevisiae GSH1 gene by hydrogen peroxide
    • Stephen, D.W.S., and Jamieson, D.J. (1997) Amino acid-dependent regulation of the Saccharomyces cerevisiae GSH1 gene by hydrogen peroxide. Mol Microbiol 23: 203-210.
    • (1997) Mol Microbiol , vol.23 , pp. 203-210
    • Stephen, D.W.S.1    Jamieson, D.J.2
  • 34
    • 0029013534 scopus 로고
    • The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae
    • Stephen, D.W.S., Rivers, S.L., and Jamieson, D.J. (1995) The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae. Mol Microbiol 16: 415-423.
    • (1995) Mol Microbiol , vol.16 , pp. 415-423
    • Stephen, D.W.S.1    Rivers, S.L.2    Jamieson, D.J.3
  • 35
    • 0034668921 scopus 로고    scopus 로고
    • Role of glutathione in heat-shock-induced cell death of Saccharomyces cerevisiae
    • Sugiyama, K., Kawamura, A., Izawa, S., and Inoue, Y. (2000) Role of glutathione in heat-shock-induced cell death of Saccharomyces cerevisiae. Biochem J 352: 71-78.
    • (2000) Biochem J , vol.352 , pp. 71-78
    • Sugiyama, K.1    Kawamura, A.2    Izawa, S.3    Inoue, Y.4
  • 36
    • 0024969387 scopus 로고
    • The function of gamma-glutamylcysteine and bis-gamma-glutamylcystine reductase in Halobacterium halobium
    • Sundquist, A.R., and Fahey, R.C. (1989) The function of gamma-glutamylcysteine and bis-gamma-glutamylcystine reductase in Halobacterium halobium. J Biol Chem 264: 719-725.
    • (1989) J Biol Chem , vol.264 , pp. 719-725
    • Sundquist, A.R.1    Fahey, R.C.2
  • 37
    • 0031457095 scopus 로고    scopus 로고
    • Metabolism of sulphur amino acids in Saccharomyces cerevsiae
    • Thomas, D., and Surdin-Kerjan, Y. (1997) Metabolism of sulphur amino acids in Saccharomyces cerevsiae. Microbiol Mol Biol Rev 61: 503-532.
    • (1997) Microbiol Mol Biol Rev , vol.61 , pp. 503-532
    • Thomas, D.1    Surdin-Kerjan, Y.2
  • 38
    • 0035896609 scopus 로고    scopus 로고
    • A proteome analysis of the cadmium response in Saccharomyces cerevisiae
    • Vido, K., Spector, D., Lagniel, G., Lopez, S., Toledano, M.B., and Labarre, J. (2001) A proteome analysis of the cadmium response in Saccharomyces cerevisiae. J Biol Chem 276: 8469-8474.
    • (2001) J Biol Chem , vol.276 , pp. 8469-8474
    • Vido, K.1    Spector, D.2    Lagniel, G.3    Lopez, S.4    Toledano, M.B.5    Labarre, J.6
  • 39
    • 0028168801 scopus 로고
    • GSH1, which encodes γ-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation
    • Wu, A., and Moye-Rowley, W.S. (1994) GSH1, which encodes g-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. Mol Cell Biol 14: 5832-5839.
    • (1994) Mol Cell Biol , vol.14 , pp. 5832-5839
    • Wu, A.1    Moye-Rowley, W.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.