Nephropathy in type 1 diabetes: A manifestation of insulin resistance and multiple genetic susceptibilities? Further evidence from the Pittsburgh Epidemiology of Diabetes Complication Study

Kidney International

Volumn 62, Issue 3, 2002, Pages 963-970

  Orchard, Trevor J ^a,b   Chang, Yue Fang ^a,b   Ferrell, Robert E ^a,b   Petro, Nancy ^a,b   Ellis, Demetrius E ^a,b  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

ACE; ApoE; Blood pressure; Diabetic nephropathy; Levels; Lipids; Predictors

Indexed keywords

ALBUMIN; APOLIPOPROTEIN E; CHOLESTEROL; DIPEPTIDYL CARBOXYPEPTIDASE; GLYCOSYLATED HEMOGLOBIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS; DIABETIC NEPHROPATHY; DISEASE PREDISPOSITION; FEMALE; FOLLOW UP; GENE DELETION; GENE INSERTION SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; HYPERINSULINISM; HYPERTENSION; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; LEUKOCYTE COUNT; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MEDICAL RESEARCH; ONSET AGE; PREVALENCE; PRIORITY JOURNAL; RISK; RISK FACTOR; URINARY EXCRETION;

EID: 0036426805     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00507.x     Document Type: Article

References (57)

1. Diabetes Epidemiology Research International Mortality Sturdy Group: International evaluation of cause-specific mortality in IDDM. Diabetes Care 14:55-60, 1990
2. Borch-Johnsen K, Kreiner S: Proteinuria: Value as predictor of cardiovascular mortality in insulin dependent diabetes mellitus. BMJ 294:1651-1654, 1987
3. Lloyd CE, Kuller LH, Becker DJ, et al: Coronary artery disease in IDDM: Gender differences in risk factors, but not risk. Arterioscler Thromb Vasc Biol 16:720-726, 1996
4. Forrest KY-Z, Becker DJ, Kuller LH, et al: Are predictors of coronary heart disease and lower extremity arterial disease in type i diabetes the same? A prospective study. Atherosclerosis 148:159-169, 2000
5. Koivisto VA, Stevens LK, Mattock MB, et al: Cardiovascular disease and its risk factors in IDDM in Europe. Diabetes Care 19:689-697, 1996
6. Orchard TJ, Stevens LK, Forrest KY-Z, Fuller JH: Cardiovascular disease in IDDM: Similar rates, but different risk factors in the United States compared with Europe. Int J Epidemiol 27:976-983, 1998
7. Coonrod BA, Ellis D, Becker D J, et al: Predictors of microalbuminutia in individuals with IDDM: Pittsburgh Epidemiology of Diabetes Complications Study. Diabetes Care 16:1376-1383, 1993
8. Haffner SM, Miettinen H: Insulin resistance implications for type II diabetes mellitus and coronary heart disease. Am J Med 103:152-162, 1997
9. Yip, J, Matlock MB, Morocutti A, et al: Insulin resistance in insulin-dependent diabetic patients with microalbuminuria. Lancet 342:883-887, 1993
10. De Cosmo S, Bacci S, Piras GP, et al: High prevalence of risk factors for cardiovascular disease in parents of IDDM patients with albuminuria. Diabetologia 40:1191-1196, 1997
11. De Cosmo S, Argiolas A, Miscio G, et al: A PC-1 amino acid variant (K121Q) is associated with faster progression of renal disease in patients with type 1 diabetes and albuminuria. Diabetes 49:521-524, 2000
12. Marre M, Bernadet P, Gallois Y, et al: Relationships between angiotensin I-converting enzyme gene polymorphism, plasma levels, and diabetic retinal and renal complications. Diabetes 43:384-388, 1994
13. Panahloo A, Andres C, Mohamed-Ali V, et al: The insertion allele of the ACE gene I/D polymorphism - A candidate gene for insulin resistance? Circulation 92:3390-3393, 1995
14. Tarnow L, Cambien F, Rossing P, et al: Lack of relationship between and insertion/deletion polymorphism in the angiotensin I-converting enzyme gene and diabetic nephropathy and proliferative retinopathy in IDDM patients. Diabetes 44:489-494, 1995
15. Jandrain B, Herbaut C, Depoorter J-C, Voorde KV: Long-term (1 year) acceptability of perindopril in type II diabetic patients with hypertension. Am J Med 92 (Suppl 4B): 915-945, 1992.
16. Jauch K-W, Hartl W, Guenther B, et al: Captopril enhances insulin responsiveness of forearm muscle tissue in non-insulin-dependent diabetes mellitus. Eur J Clin Invest 17:448-454, 1987
17. Pollare T, Lithell H, Berne C: A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N Engl J Med 321:868-873, 1989
18. Davignon J, Gregg RE, Sing CF: Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 8:1-21, 1988
19. Orchard TJ, Eichner JE, Kuller LH, et al: Insulin as a predictor of coronary heart disease: Interaction with Apo E phenotype. A report from MRFIT. Ann Epidemiol 4:40-45, 1994
20. Craft S, Asthana S, Schellenberg G, et al: Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype. Ann N Y Acad Sci 903:222-228, 2000
21. Araki S, Moczulski DK, Hanna L, et al: APOE polymorphisms and the development of diabetic neuropathy in type 1 diabetes - Results of case-control and family-based studies. Diabetes 49:2190-2195, 2000
22. Chowdhury TA, Dyer PH, Kumar S, et al: Association of apolipoprotein E2 allele with diabetic nephropathy in Caucasian subjects with IDDM. Diabetes 47:278-280, 1998
23. Eto M, Horita K, Morikawa A, et al: Increased frequency of apolipoprotein E2 allele in non-insulin dependent diabetic (NIDDM) patients with nephropathy. Clin Genet 48:288-292, 1995
24. Onuma T, Laffel LM, Angelico MC, Krolewski AS: Apolipo-protein E genotypes and risk of diabetic nephropathy. J Am Soc Nephrol 7:1075-1078, 1996
25. Kimura H, Suzuki Y, Geiyo F, et al: Apolipoprotein E4 reduces risk of diabetic nephropathy in patients with NIDDM. Am J Kidney Dis 31:666-673, 1998
26. Boize R, Benhamou P-Y, Corticelli P, et al: ApoE polymorphism and albuminuria in diabetes mellitus: A role for LDL in the development of nephropathy in NIDDM? Nephrol Dial Transplant 13:72-75, 1998
27. Williams KV, Erbey JR, Becker D, et al: Can clinical factors estimate insulin resistance in type 1 diabetes? Diabetes 49:626-632, 2000
28. Orchard TJ, Dorman JS, Maser RE, et al: Factors associated with the avoidance of severe complications after 25 years of insulin dependent diabetes mellitus: Pittsburgh Epidemiology of Diabetes Complications Study - I. Diabetes Care 13:741-747, 1990
29. Orchard TJ, Dorman JS, Maser RE, et al: The prevalence of complications in insulin dependent diabetes mellitus by sex and duration: Pittsburgh Epidemiology of Diabetes Complications Study - II. Diabetes 39:1116-1124, 1990
30. Borhani NO, Kass EH, Langford HG, et al: The hypertension detection and follow-up program. Prev Med 5:207-215, 1976
31. Warnick GR, Albers JJ: Heparin-Mn2+ quantitaion of high density lipoprotein cholesterol: An ultrafiltration procedure for lipemic samples. Clin Chem 24:900-904, 1978
32. National Institutes of Health: Department of Health: Lipid Research Clinics Program. Washington, D.C., U.S. Government Printing Office, 1975, pp 75-628.
33. Allain CC, Poon LS, Chan CSG, et al: Enzymatic determination of total serum cholesterol. Clin Chem 20:470-475, 1974
34. Bucolo G, David H: Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 19:476-482, 1973
35. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502, 1972
36. Ellis D, Buffone GJ: New approach to evaluation of proteinuric states. Clin Chem 23:666-670, 1977
37. DCCT Research Group: DCCT Manual of Operations, 1993; Springfield, VA, Department of Commerce, National Technical Information Service, 1993, pp 183-382
38. Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215, 1988
39. Hixson JE, Vernier DT: Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HpaI. J Lipid Res 31:545-548, 1990
40. Tiret L, Rigat B, Visvikin S, et al: Evidence from combined linkage and segregation analysis that a variant of the ACE gene controls plasma ACE levels. Am J Human Genet 51:197-205, 1992
41. Ahn Y, Kamboh MI, Hamman RF, et al: Two DNA polymorphisms in the LPL gene and their associations with factors related to cardiovascular disease. J Lipid Res 34:421-428, 1993
42. Wagener DK, Sacks JM, LaPorte RE, MacGregor JM: The Pittsburgh Study of Insulin-Dependent Diabetes Mellitus: Risk for diabetes among relatives of IDDM. Diabetes 31:136-144, 1982
43. Ronnemaa T, Laakso M, Kallio V, et al: Serum lipids, lipoproteins, and apolipoproteins and the excessive occurrence of coronary heart disease in non-insulin-dependent diabetic patients. Am J Epidemiol 130:632-645, 1980
44. Haffner SM: The insulin resistance syndrome revisited. Diabetes Care 19:275-277, 1996
45. Reaven GM: Role of insulin resistance in human disease. Diabetes 37:1595-1607, 1988
46. Krolewski AS, Fogarty DG, Warram JH: Hypertension and nephropathy in diabetes mellitus: What is inherited and what is acquired? Diabetes Res Clin Pract 39 (Suppl 1): S1-S14, 1998.
47. Epidemiology of Diabetes Interventions and Complications Research Group: Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N Engl J Med 342:381-389, 2000
48. Mogensen CE: Microalbuminuria, blood pressure and diabetic renal disease: Origin and development of ideas. Diabetologia 42:263-285, 1999
49. orchard TJ, Forrest KY-Z, Ellis D, Becker DJ: Cumulative glycemic exposure and microvascular complications in insulin-dependent diabetes mellitus. Arch Intern Med 157:1851-1856, 1997
50. Caramori ML, Fioretto P, Mauer M: The need for early predictors of diabetic nephropathy risk - Is albumin excretion rate sufficient? Diabetes 49:1399-1408, 2000
51. Control and Complications Trial Research Group: Effect of intensive therapy on the development and progression of diabetic nephropathy in the diabetes control and complications trial. Kidney Int 47:1703-1720, 1995
52. Warram JH, Scott LJ, Hanna LS, et al: Progression of microalbuminuria to proteinuria in type 1 diabetes. Diabetes 49:94-100, 2000
53. Nowalk MP, Stuhldreher WL, Becker D, et al: The relationship of protein intake to changes in renal function in an adult population with insulin-dependent diabetes mellitus. Diabetes Nutr Metab 9:247-257, 1996
54. Orchard TJ: From diagnosis and classification to complication and therapy: DCCT part II? The 1993 Kelly West Lecture. Diabetes Care 17:326-338, 1994
55. Wilkin TJ: Early nutrition and diabetes mellitus. Nutrition during fetal life and infancy may be crucial to the development of diabetes mellitus. Br Med J 306:283-284, 1993
56. Onuma T, Laffel LM, Angelico MC, Krolewski AS: Apolipoprotein E genotypes and risk of diabetic nephropathy. J Am Soc Nephrol 7:1075-1078, 1996
57. Soedamah-Muthu SS, Colhoun HM, Taskinen M-R, et al: Differences in HDL-cholesterol:apoA-I + apoA-II ratio and apoE phenotype with albuminuric status in type I diabetic patients. Diabetologia 43:1353-1359, 2000