The application of multi-component reactions in drug discovery

Current Medicinal Chemistry

Volumn 9, Issue 23, 2002, Pages 2085-2093

  Weber, Lutz ^a  

^a Morphochem AG   (Germany)

Author keywords

Chemical diversity; Chemical libraries; Diversity oriented synthesis; Drug discovery; Lead finding; Lead optimisation; MCR; Multi component reactions

Indexed keywords

ARTICAINE; BESTATIN; BETA LACTAM DERIVATIVE; BLOOD CLOTTING FACTOR 10A INHIBITOR; BLOOD CLOTTING FACTOR 7A; CARBACEPHEM DERIVATIVE; CARBAPENEM; CEPHALOSPORIN DERIVATIVE; CLODACAINE; ENZYME INHIBITOR; HETEROCYCLIC COMPOUND; HIRSUTINE; HYDROXYAMINO ACID; HYDROXYLAMINE; INDINAVIR; LIDOCAINE; LOCAL ANESTHETIC AGENT; MALEIC ACID DERIVATIVE; MD 639; NIFEDIPINE; NIFEDIPINE DERIVATIVE; NOCARDICIN A; PENICILLIN DERIVATIVE; PHOSPHOTRANSFERASE INHIBITOR; PRILOCAINE; PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR; THROMBIN INHIBITOR; TRABECTEDIN; TRYPTOLINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; BIOLOGICAL FACTOR; DRUG;

ARTICLE; CHEMICAL REACTION; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; CONTROLLED STUDY; DRUG MANUFACTURE; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; HUMAN; METHODOLOGY; REVIEW; SYNTHESIS;

ANIMALS; BIOLOGICAL FACTORS; CHEMISTRY, PHARMACEUTICAL; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS; HUMANS; PHARMACEUTICAL PREPARATIONS;

EID: 0036424932     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867023368719     Document Type: Article

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