Effect of intranasal administration of CV-11974, a type 1 angiotensin II receptor antagonist, on airway hyperresponsiveness and airway inflammation induced by antigen inhalation in guinea pigs

International Archives of Allergy and Immunology

Volumn 129, Issue 1, 2002, Pages 86-92

  Myou, Shigeharu ^a,b   Fujimura, Masaki ^a   Kita, Toshiyuki ^a   Watanabe, Kazuyoshi ^a   Hirose, Tatsuki ^a   Tachibana, Hideki ^a   Ishiura, Yoshihisa ^a   Nakao, Shinji ^a  

^a KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

^b NONE   (United States)

Author keywords

Airway hyperresponsiveness; Airway inflammation; Angiotensin II; Antigen challenge; CV 11974; Eosinophils; Guinea pigs; Methacholine; PD123319

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIGEN; CANDESARTAN;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOSPASM; CONTROLLED STUDY; DOSE RESPONSE; EOSINOPHIL; EOSINOPHILIA; EXPOSURE; GUINEA PIG; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION;

ADMINISTRATION, INHALATION; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIGENS; BENZIMIDAZOLES; BRONCHIAL HYPERREACTIVITY; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; GUINEA PIGS; IMIDAZOLES; MALE; PYRIDINES; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; TETRAZOLES;

EID: 0036422746     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000065177     Document Type: Article

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