Early markers of nephrotoxicity

Comparative Clinical Pathology

Volumn 11, Issue 1, 2002, Pages 2-7

  Price, R G ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Biomarkers; Core tests; Early detection; Enzymuria; Nephrotoxicity; Proteinuria

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; CISPLATIN; CYCLOSPORIN; FIBRONECTIN; FUNGICIDE; GLYCOL; GLYCOSAMINOGLYCAN; HEAVY METAL; HERBICIDE; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENT; INSECTICIDE; MYCOTOXIN; N ACETYL BETA GLUCOSAMINIDASE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; RETINOL BINDING PROTEIN; TAMM HORSFALL GLYCOPROTEIN; THROMBOXANE B2; TRANSFERRIN; UNINDEXED DRUG;

ACCURACY; ARTICLE; CONTROLLED STUDY; DETERIORATION; DISEASE COURSE; DISEASE SEVERITY; EXPOSURE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY DYSFUNCTION; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY INJURY; NEPHRON; NEPHROTOXICITY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RANDOMIZATION; RISK ASSESSMENT; SCREENING TEST; SENSITIVITY ANALYSIS; TREATMENT PLANNING; URINALYSIS;

EID: 0036414586     PISSN: 16185641     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00010011     Document Type: Article

References (23)

1. Branten AJ, Mulder TP, Peters WH et al. (2000) Urinary excretion of glutathione S-transferase α and π: a refection of the site of tubular injury. Nephron 85:111-114
2. Cardenas A, Roels H, Barbon R et al. (1993a) Markers of early renal changes induced by industrial pollutants I. Application to workers exposed to mercury vapour. Br J Ind Med 50:17-27
3. Cardenas A, Roels H, Barbon R et al. (1993b) Markers of early renal changes induced by industrial pollutants II. Application to workers exposed to lead. Br J Ind Med 50:28-36
4. Fels LM, Bundschuh I, Gwinner W et al. (1994a) Early urinary markers of target nephron segments as studied in cadmium toxicity. Kid Int 46(Suppl. 47):S81-88
5. Fels LM, Herbort C, Ppergrand E et al. (1994b) Nephron target sites in chronic exposure to lead. Nephrol Dial Transpl 9:1740-1746
6. Fels LM, Wunsch M, Baranowski J et al. (1998) Adverse effects of chronic low level lead exposure on kidney function - a risk group study in children. Nephrol Dial Transpl 13:2248-2256
7. Finn WF (1995) Biologic markers in urinary toxicology. National Academy Press, Washington, pp 1-305
8. Guder WG, Ross BD (1984) Enzyme distribution along the nephron. Kid Int 26:101-111
9. Halman J, Miller J, Fowler JSL et al. (1986) Renal toxicity of propyleneimine: assessment by non-invasive techniques in the rat. Toxicology 41:43-59
10. IPCS (International Programme on Chemical Safety) (1991) Principles and methods for the assessment of nephrotoxicity associated with exposure to chemicals. WHO Geneva Environ Health Criteria 119:1-266
11. Mueller PW, Price RG, Porter GA (1997) Urinary biomarkers to detect significant effects of environmental and occupational exposure to nephrotoxins - overview. Ren Fail 19(4):501-504
12. Mutti A, Alvinovi E, Bergamaschi E et al. (1992) Nephropathies and exposure to organic solvents: a survey of dry-cleaners exposed to perchloroethylene. Lancet 340:189-193
13. Price RG (1982) Urinary enzymes, nephrotoxicity and renal disease. Toxicology 23:99-134
14. Price RG (1992) The measurement of urinary N-acetyl-β-D-glucosaminidase (NAG) amd its isoenzymes: methods and clinical applications. Eur J Clin Chem Clin Biochem. 30:693-705
15. Price RG (2000) Urinalysis to exclude and monitor nephrotoxicity. Clin Chim Acta 297:173-182
16. Price RG, Whiting PH (1992) Urinary enzymes and nephrotoxicity in humans. In: Jung K, Mattenheimer H, Burchardt U (eds) Urinary enzymes in clinical and experimental medicine. Springer-Verlag, Heidelberg, pp 202-221
17. Price RG, Taylor SA, Chivers I et al. (1996) Development and validation of new screening tests for nephrotoxic effects. Hum Exp Toxicol 15:810-819
18. Price RG, Berndt WO, Finn WF et al. (1997) Urinary bio-markers to detect significant effects of environmental and occupational exposure to nephrotoxins: III-Minimal battery of tests to assess subclinical nephrotoxicity for epidemiological studies based on current knowledge. Ren Fail 19(4):535-552
19. Price RG, Patel S, Chivers I et al. (1999a) Early markers of nephrotoxicity: detection of children at risk from environmental pollution. Ren Fail 21:303-308
20. Price RG, Weeden R, Litchveld MY et al. (1999b) Urinary biomarkers: role in risk assessment to environmental and occupational nephrotoxins: monitoring the effects and evaluation of mechanisms of toxicity. Ren Fail 21:xiii-xviii
21. Roels H, Bernard AM, Cardenas A et al. (1993) Markers of early renal changes induced by industrial pollutants III: Application to workers exposed to cadmium. Br J Ind Med 50:37-48
22. Swierczek S, Price RG, Abuknesha RA (2000) Determination of metallothioneins by ELISA as a procedure for assessing metal toxicity. VI Polska Konferencj Chemii Analitycznej, Gliwice, pp 313
23. Taylor SA, Chivers ID, Price RG et al. (1997) The assessment of the utility of biomarkers to detect nephrotoxicity using an integrated database. Environ Res 75:23-33