Botryococcus braunii: A renewable source of hydrocarbons and other chemicals

Critical Reviews in Biotechnology

Volumn 22, Issue 3, 2002, Pages 245-279

  Banerjee, Anirban ^a   Sharma, Rohit ^a   Chisti, Yusuf ^b   Banerjee, U C ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b MASSEY UNIVERSITY   (New Zealand)

Author keywords

Algal culture; Algal hydrocarbons; Botryococcene; Botryococcus braunii; Microalgae; Photobioreactors

Indexed keywords

ALGAE; CELL CULTURE; CLONING; FOSSIL FUELS; GENES; HYDROCARBONS; MICROBIOLOGY; MICROORGANISMS; PHYSIOLOGY;

FACETS;

BIOTECHNOLOGY;

FOSSIL FUEL; HYDROCARBON; INORGANIC COMPOUND;

ALGAL CELL CULTURE; BIOSYNTHESIS; BIOTECHNOLOGY; BOTRYOCOCCUS BRAUNII; CHEMICAL INDUSTRY; DRY MASS; GREEN ALGA; MICROBIOLOGY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REVIEW; SUNLIGHT;

ALGAE, GREEN; BIOTECHNOLOGY; HYDROCARBONS;

ALGAE; BOTRYOCOCCUS BRAUNII; CHLOROPHYTA;

EID: 0036407352     PISSN: 07388551     EISSN: None     Source Type: Journal    
DOI: 10.1080/07388550290789513     Document Type: Review

References (117)

1. Acién Fernández, F. G., Fernández Sevilla, J. M., Sánchez Pérez, J. A., Molina Grima, E., and Chisti, Y. 2001. Airlift-driven external-loop tubular photobioreactors for outdoor production of microalgae: assessment of design and performance. Chem. Eng. Sci. 56: 2721.
2. Allard, B. and Casadevall, E. 1990. Carbohydrate composition and characterisation of sugars from the green microalga Botryococcus braunii. Phytochem. 29: 1875.
3. Anderson, D. B. and Eakin, D. E. 1985. A process for the production of polysaccharides from microalgae. Biotechnol. Bioeng. Symp. 15: 533.
4. Bailliez, C., Largeau, C., and Casadevall, E. 1985. Growth and hydrocarbon production of Botryococcus braunii immobilized in calcium alginate gel. Appl. Microbiol. Biotechnol. 23: 99.
5. Bailliez, C., Largeau, C., Berkaloff, C., and Casadevall, E. 1986. Immobilization of Botryococcus braunii in alginate, influence on chlorophyll content, photosynthetic activity and degeneration during batch culture. Appl. Microbiol. Biotechnol. 23: 361.
6. Bailliez, C., Largeau, C., Casadevall, E., Yang, L. W., and Berkaloff, C. 1988. Photosynthesis, growth and hydrocarbon production of Botryococcus braunii immobilized by entrapment and adsorption in polyurethane foams. Appl. Microbiol. Biotechnol. 29: 141.
7. Behrens, A., Schaeffer, P., Bernasconi, S., and Alrecht, P. 2000. 7,11-cyclobotryococca 5,12,26-triene, a novel botryococcene related hydrocarbon occurring in environment. Organic Lett. 2: 1271.
8. Belarbi, E. H., Molina, E., and Chisti, Y. 2000. A process for high yield and scaleable recovery of high purity eicosapentaenoic acid esters from microalgae and fish oil. Enzyme Microb. Technol. 26: 516.
9. Ben-Amotz, A., Torbene, T. G., and Thomas, W. H. 1985. Chemical profile of selected species of microalgae with emphasis on lipids. J. Phycol. 21: 72.
10. Bertheas, O., Metzger, P., and Largeau, C. 1999. A high molecular weight complex lipid, aliphatic polyaldehyde tetraterpene diol polyacetal from race L of Botryococcus braunii. Phytochemistry 50: 85.
11. Blackburn, K. B. 1936. Botryococcus and algal coal. Trans. R. Soc. Edin. 58: 841.
12. Brenckman, F., Largeau, C., Casadevall, E., and Berkaloff, C. 1989. Effect of nitrogen nutrition on growth and hydrocarbon production of the unicellular microalga Botryococcus braunii. Comm. Eur. Communities, Energy Biomass 717.
13. Brown, A. G. and Knights, B. A. 1969. Hydrocarbon content and it's relationship to physiological state in the green alga Botryococcus braunii. Phytochemistry 8: 543.
14. Cane, R. F. 1977. Coorongite, balkashite and related substances-an annotated bibliography. Trans. R. Soc. S. Aust. 101: 153.
15. Casadevall, E., Largeau, C., Metzger, P., Chirac, C., Berkaloff, C., and Coute, A. 1983. Hydrocarbon production by unicellular microalga Botryococcus braunii. Biosciences 2: 129.
16. Casadevall, E., Dif, D., Largeau, C., Gudin, C., Chamount, D., and Desanti, O. 1985. Studies on batch and continuous culture of Botryococcus braunii: hydrocarbon production in relation to physiological state, cell ultrastructure and phosphate nutrition. Biotechnol. Bioeng. 27: 286.
17. Chirac, C., Casadevall, E., Largeau, C., and Metzger, P. 1985. Bacterial influence upon growth and hydrocarbon production of the alga Botryococcus braunii. J. Phycol. 21: 380.
18. Chisti, Y. 1980. An unusual hydrocarbon. J. Ramsay Society 27-28: 24-26.
19. Chisti, Y. 1989. Airlift Bioreactors, Elsevier, London.
20. Chisti, Y. 1998. Strategies in downstream processing. In Bioseparation and Bioprocessing: A Handbook, vol. 2, Subramanian, G., Ed., Wiley-VCH, New York, 3.
21. Chisti, Y. 1999. Shear sensitivity. In: Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis, and Bioseparation, vol. 5, Flickinger, M. C. and Drew, S. W., Eds., Wiley, New York, 2379.
22. David, M., Metzger, P., and Casadevall, E. 1988. Two cyclobotryococcenes from the B race of green alga Botryococcus braunii. Phytochemistry 27: 2863.
23. Dennis, M. W. and Kolattukudy, P. E. 1991. Alkane biosynthesis by decarbonylation of aldehyde catalyzed by a microsomal preparation from Botryococcus braunii. Arch. Biochem. Biophys. 287: 268.
24. Derenne, S., Largeau, C., Casadevall, E., and Connan, J. 1988. Mechanism of formation and chemical structure of coorongite. Structure and origin of the labile fraction. Fate of botryococcenes during early diagenesis. Org. Geochem. 13: 965.
25. Dernne, S., Largeau, C., Casadevall, E., and Berkaloff, C. 1989. Comparative study of rat and tobacco squalene. Phytochemistry 38: 1137.
26. Dote, Y., Sawayama, S., and Yokoyama, S. 1992. Liquefaction of hydrocarbon-rich microalga. Am. Chem. Soc. Div. Fuel Chem. 37: 1836.
27. Fallon, R. D. and Brock, T. D. 1979. Decomposition of blue green algal (cyanobacterial) blooms in lake Mendota, Wisconsin. Appl. Environ. Microbiol. 37: 820.
28. Fernandes, H. L., Tomme, M. M., Lupi, F. M., Fialho, A. M., Sa Correia, I., and Novais, J. M. 1989. Biosynthesis of high concentration of an exopolysaccharide during cultivation of the microalga Botryococcus braunii. Biotechnol. Lett. 11: 433.
29. Frenz, J., Largeau, C., and Casadevall, E. 1989a. Hydrocarbon recovery by extraction with a biocompatible solvent from free and immobilized cultures of Botryococcus braunii. Enzyme Microb. Technol. 11: 717.
30. Frenz, Z., Largeau, C., Csadevall, C., Kollerup, F., and Daugulis, A. J. 1989b. Hydrocarbon recovery and biocompatibility of solvents for extraction from cultures of Botryococcus braunii. Biotechnol. Bioeng. 34: 755.
31. Gelpi, E., Schneider, H., Mann, J., and Oro, J. 1970. Hydrocarbons of geochemical significance in microscopic algae. Phytochemistry 9: 603.
32. Goodway, G. W., Fawcett, P., Green, D., and Shaw, G. 1973. Sporopollenin formation in the ascospore wall of Neurospora crassa. Arch. Microbiol. 101: 145.
33. Grung, M., Metzger, P., and Liaaen-Jensen, S. 1989. Algal carotenoids, primary and secondary carotenoids in two races of green alga Botryococcus braunii. Biochem. Sys. Eco. 17: 263.
34. Grung, M., Metzger, P., and Liaaen-Jensen, S. 1994. Secondary carotenoids in Botryococcus braunii race L, new strain. Biochem. Sys. Eco. 22: 25.
35. Gu, P., Ishii, Y., Spencer, T. A., and Shechter, I. 1998. Function-structure studies and identification of three enzyme domain involved in the catalytic activity in rat hepatic squalene synthase. J. Biol. Chem. 273: 12515
36. Gudin, C. and Thomas, D. 1981. Production de polysaccharides sulfates par un biophotoreacteur a cellules immobilisees de Porphyridium curentum. C. R. Sci. Paris 293: 35.
37. Gudin, C., Bernard, A., Chaumont, D. T., Thepnier, C., and Hardy, T. 1984. Direct conversion of solar energy into organic chemicals. World Biotech. Rep. 1: 541.
38. Guzman-Murillo, M. A. and Ascencio, F. 2000. Anti adhesive activity of sulfated polysaccharides of microalgae on attachment of red sore disease-associated bacteria and Helicobacter pylori to tissue culture cells. Lett. Appl. Microbiol. 30: 473.
39. 12 producing marine bacteria. J. Phycol. 10: 245.
40. Held, W., Peters, M., Buhs, C., Oelert, H. H., Reifenstahl, G., and Wagner, F. 1985. Production of hydrocarbon from biomass. Comm. Eur. Communities, Energy Biomass 744.
41. Huang, Z., Poulter, C. D., Wolf, F. R., Somers, T. C., and White, J. D. 1988. Braunicene, a novel cyclic C32 isoprenoid from Botryococcus braunii. J. Am. Chem. Soc. 110: 3959.
42. Huang, J. and Poulter, C. D. 1989. Tetramethyl squalene, a triterpene from Botryococcus braunii var showa. Phytochem. 28: 1467.
43. Inone, H., Korenaga, T., Sagami, H., Koyama, T., Sugiyama, H., and Ogura, K. 1993. Formation of farnesal and 3-hydroxy-2,3-dihydrofarnesal from farnesal by protoplasts of Botryococcus braunii. Biochem. Biophys. Res. Commun. 196: 1401.
44. Inone, H., Korenaga, T., Sagami, H., and Ogura, K. 1994a. Phosphorylation of farnesol by a cell free system of Botryococcus braunii. Biochem. Biophys. Res. Commun. 200: 1036.
45. Inoue, S., Dote, Y., Sawayama, S., Minowa, T., Ogi, T., and Yokoyama, S. 1994b. Analysis of oil derived from liquefaction of Botryococcus braunii. Biomass Bioenergy 6: 269.
46. Jarstfer, M. B., Blagg, B. S. J., Rogers, D. H., and Poulter, C. D. 1996. Biosynthesis of squalene. Evidence for a tertiary cyclopropylcarbinyl cationic intermediate in the rearrangement of presqualene diphosphateto squalene. J. Am. Chem. Soc. 118: 13089.
47. Jones, J. G. 1972. Studies on freshwater bacteria: association with algae and alkaline phosphatase activity. J. Ecol. 60: 59.
48. Kitazato, H., Asaoka, S., and Iwamoto, H. 1989. Catalytic cracking of hydrocarbons from microalgae. Sekiyu Gakkaishi 32: 28.
49. Kojima, E. and Zhang, K. 1999. Growth and hydrocarbon production by microalga Botryococcus braunii in bubble column photobioreactor. J. Bioscience Bioeng. 87: 811.
50. Koren, K. M. and Rayburn, W. R. 1984. Influence of growth status and nutrients on exocellular polysaccharides synthesis by the soil alga Chlamydomonas mexicana. J. Phycol. 20: 253.
51. Lareillard, J., Largeau, C., and Casadevall, E. 1988. Oleic acid in the biosynthesis of resistant polymer of Botryococcus braunii. Phytochemistry 27: 2095.
52. Largeau, C., Casadevall, E., Berkaloff, C., and Dhamliencourt, P. 1980. Sites of accumulation and composition of hydrocarbons in Botryococcus braunii. Phytochemistry 19: 1043.
53. Lee, S. J., Kim, S. B., Kim, H. S., Kwon, G. S., Yoon, B. D., and Oh, H. M. 1999. Mass cultivation of Botryococcus braunii for advanced treatment of swine waste water and lipid production in photobioreactor. Sanop Misaengmul Hakhoechi 27: 166.
54. Lichitfouse, E., Derenne, S., Mariotti, A., and Largeau, C. 1994. Possible algal origin of long chain odd n-alkanes in immature sediments as revealed by distribution and carbon isotope ratios. Org. Geochem. 22: 1023.
55. Lupi, F. M., Fernandes, H. M. L., Sa Correia, I., and Novais, J. M. 1991. Temperature profiles of cellular growth exopolysaccharide synthesis by Botryococcus braunii. J. Phycol. 3: 35.
56. Lupi, F. M., Fernandes, H. M. L., Tomme, M. M., Sa Correia, I., and Novais, J. M. 1994. Influence of nitrogen source and photoperiod on exopolysaccharide synthesis by the microalga Botryococcus braunii. Enzyme Microb. Technol. 16: 546.
57. McIrdy, D. M., Cox, R. E., Vlkman, J. K., and Howel, V. J. 1986. Botryococcane in a new class of Australian non marine crude oils. Nature 320: 57.
58. 2 extraction to microalgae and plants. J. Chem. Technol. Biotechnol. 62: 53.
59. Metzger, P., Berkaloff, C., Casadevall, E., and Coute, A. 1985a. Alkadiene and botryococcene producing races of wild strains of Botryococcus braunii. Phytochem. 24: 2305.
60. Metzger, P., Casadevall, E., Pouet, M. J., and Pouet, Y. 1985b. Structure of some botryococcenes: branched hydrocarbons from the B race of the green alga Botryococcus braunii. Phytochem. 24: 2995.
61. Metzger, P. and Casadevall, E. 1987. Lycopadiene, a tetraterpenoid hydrocarbon from new strains of the green alga Botryococcus braunii. Tetrahedron Lett. 24: 2305.
62. Metzger, P., David, M., and Casadevall, E. 1987. Bio-synthesis of triterpenoid hydrocarbons in the B race of green alga Botryococcus braunii. Sites of production and nature of methylating agent. Phytochem. 26: 129.
63. Metzger, P., Casadevall, E., and Coute, A. 1988. Botryococcene distribution in strains of green alga Botryococcus braunii. Phytochemistry 27: 1383.
64. Metzger, P. and Casadevall, E. 1989. Aldehydes, very long chain alkenyl phenols, epoxides and other lipids from an alkadiene producing strain of Botryococcus braunii. Phytochemistry 28: 2097.
65. Metzger, P., Allard, B., Casadevall, E., Berkaloff, C., and Coute, A. 1990. Structure and chemistry of a new chemical race of Botryococcus braunii (chlorophyceae) that produces lycopadiene, a tetraterpenoid hydrocarbon. J. Phycol. 26: 258.
66. Metzger, P. and Casadevall, E. 1991. Botryococcoid ethers, ether lipids from Botryococcus braunii. Phytochemistry 30: 1439.
67. Metzger, P., Villarreal-Rosales, E., and Casadevall, E. 1991. Methyl branched fatty aldehydes and fatty acids in Botryococcus braunii. Phytochemistry 30: 185.
68. Metzger, P. and Casadevall, E. 1992. Ether lipids from Botryococcus braunii and their biosynthesis. Phytochemistry 31: 2341.
69. Metzger, P. and Pouet, Y. 1995. n-Alkyl pyrogallol dimethyl ethers, aliphatic diol monoesters and some minor ether lipids from Botryococcus braunii (A race). Phytochemistry 40: 543.
70. Metzger, P. and Aumelas, A. 1997. Lycopanerol-A, di-tetraterpenoid tetraether derivatives from green microalga Botryococcus braunii L race. Tetrahedron Lett. 38: 2977.
71. Mirón, A. S., Gómez, A. C., Camacho, F. G., Grima, E. M., and Chisti, Y. 1999. Comparative evaluation of compact photobioreactors for large-scale monoculture of microalgae. J. Biotechnol. 70: 249.
72. Mirón, A. S., Camacho, F. G., Gómez, A. C., Grima, E. M., and Chisti, Y. 2000. Bubble column and airlift photobioreactors for algal culture. AIChE J. 46: 1872.
73. Moldwan, J. M. and Seifert, W. K. 1980. First discovery of botryococcane in petroleum. J. C. S. Chem. Commun. 1: 912.
74. Molina, E., Fernández, F. G. A., Camacho, F. G., and Chisti, Y. 1999. Photobioreactors: light regime, mass transfer, and scaleup. J. Biotechnol. 70: 231.
75. Molina, E., Acién Fernández, F. G., García Camacho, F., Camacho Rubio, F., and Chisti, Y. 2000. Scale-up of tubular photobioreactors. J. Appl. Phycol. 12: 355.
76. Molina, E., Fernández, J., Acién, F. G., and Chisti, Y., 2001. Tubular photobioreactor design for algal cultures. J. Biotechnol. 92: 113.
77. Murakami, M., Nakano, H., Yamaguchi, K., Konosu, S., Nakayama, O., Matsumoto, Y., and Iwamoto, H. 1988. Meijicoccene, a new cyclic hydrocarbon from Botryococcus braunii. Phytochemistry 27: 455.
78. Murakami, N. 2000. Plant growth regulator composition and their manufacture. Jpn. Kokai Tokkyo Koho 264: 809.
79. Murry, J. and Thomson, A. 1977. Hydrocarbon production in Anacystis montana and Botryococcus braunii. Phytochemistry 16: 465.
80. Oh, H. M., Kim, S., Park, E. R., Lee, S. T., Kwon, J. S., and Yoon, B. D. 1997. Effects of light intensity and nutrients on the growth of Botryococcus sp. Misaengmul Hakhoechi 25: 339.
81. Ohmori, M., Wolf, F. R., and Bassham, J. A. 1984. Botryococcus braunii carbon/nitrogen metabolism as affected by ammonia addition. Arch. Microbiol. 140: 101.
82. Okada, S., Mastuda, M., and Yamaguchi, K. 1996. Botryoxanthin-A a new member of the new class of carotenoids from green microalga Botryococcus braunii, Berkeley. Tetrahedron Lett. 37: 1065.
83. Okada, S., Tonegawa, I., Mastuda, H., Murakami, M., and Yamaguchi, K. 1997. Carotenoids from green microalga Botryococcus braunii. Tetrahedron 53: 11307.
84. Okada, S., Tonegawa, I., Mastuda, H., Murakami, M., and Yamaguchi, K. 1998. Botryoxanthin-B and alpha botryoxanthin-A from green microalga Botryococcus braunii. Phytochemistry 47: 1111.
85. Okada, S., Devarenne, T. P., and Chappel, J. 2000. Molecular characterization of squalene synthase from the green alga Botryococcus braunii, race B. Arch. Biochem. Biophys. 373: 307.
86. Parker, B. C. and Bold, H. C. 1961. Biotic relationships between soil algae and other microorganisms. Am. J. Botany 48: 185.
87. 2H] chrysanthemyloxy]-pyridinium iodide. J. Am. Chem. Soc. 99: 3824.
88. Poulter, C. D., Marsh, L., Argyle, J. C., Dennis, M. S., Robyn, J. G., and Scott, G. M. 1977. Model studies of biosynthesis of non-head to tail terpenes. Rearrangements of the chrysanthemyl system. J. Am. Chem. Soc. 99: 3816.
89. Rager, M. N. and Metzger, P. 2000. Six novel tetraterpenoid ethers, lycopanerols B-G, and some other constituents from green microalga Botryococcus braunii. Phytochemistry 54: 427.
90. Reim, R. L., Shane, M. S., and Cannon, R. E. 1974. The characterization of a Bacillus capable of blue green bactericidal activity. Can. J. Microbiol. 20: 981.
91. Robinson, G. Y., Tsay, Y. H., Kienzle, B. K., Smith-Monroy, C. A., and Bishop, R. W. 1993. Conservation between human and fungal squalene synthases: similarities in structure, function and regulation. Mol. Cell Biol. 13: 2706.
92. Saks, N. M. and Kahn, E. G. 1979. Substrate competition between a salt marsh diatom and a bacterial population. J. Phycol. 15: 17.
93. Sawayama, S., Minowa, T., Dote, Y., and Yokoyama, S. 1992. Growth of the hydrocarbon rich microalga Botryococcus braunii in secondarily treated sewage. Appl. Microbiol. Biotechnol. 38: 135.
94. Sawayama, S., Inone, S., and Tokoyama, S. 1994. Continuous culture of hydrocarbon rich microalga Botryococcus braunii secondarily treated sewage. Appl. Microbiol. Biotechnol. 41: 729.
95. Sawayama, S., Inoue, S., and Yokoyama, S. 1995. Phylogenetic position of Botryococcus braunii based on small subunit of ribosomal RNA sequence data. J. Phycol. 31: 419.
96. Sawayama, S., Minowa, T., and Yokoyama, S. 1999. Possibility of renewable energy production and carbon dioxide mitigation by thermochemical liquefaction of microalgae. Biomass Bioenergy 17: 33.
97. Swale, E. M. F. 1968. The phytoplankton of Oakmere, Cheshire. Br. Phycol. Bull. 3: 441.
98. Templier, J., Largeau, C., and Casadevall, E. 1984. Hydrocarbon formation in the green alga Botryococcus braunii and mechanism of non-isoprenoid hydrocarbon biosynthesis. Phytochem. 23: 1017.
99. Templier, J., Largeau, C., and Casadevall, E. 1991a. Biosynthesis of n-alkatrienes in Botryococcus braunii. Phytochemistry 30: 2209.
100. Templier, J., Largeau, C., and Casadevall, E. 1991b. Non-specific elongation-decarboxylation in biosynthesis of cis and trans-alkadienes by Botryococcus braunii. Phytochemistry 30: 175.
101. Templier, J., Disendorf, C., Largeau, C., and Casadevall, E. 1992a. Metabolism of n-alkadienes in the A race of Botryococcus braunii. Phytochemistry 31: 113.
102. Templier, J., Largeau, C., and Casadevall, E. 1992b. Chemical inhibition of resistant biopolymers in the outer walls of A and B races of Botryococcus braunii. Phytochemistry 31: 4097.
103. Templier, J., Largeau, C., and Casadevall, E. 1993. Variation in external and internal lipid associated with inhibition of resistant biopolymer from the A race of Botryococcus braunii. Phytochemistry 33: 1079.
104. Tonegawa, I., Okada, S., Murakami, M., and Yamaguchi, K. 1998. Pigment composition of the green microalga Botryococcus braunii, Kawaguchi. Fish Sc. 64: 305.
105. Vanquez, R. and Bertha, O. 1991. Haloadaption of the green alga Botryococcus braunii. Phytochemistry 30: 2919.
106. Volova, T. G., Kalacheva, G. S., Zhilo, N. O., and Plotnicov, V. F. 1998. Physiological and biochemical properties of the alga Botryococcus braunii. Russ. J. Plant. Physol. 45: 725.
107. Wake, L. V. and Hillen, L. W. 1981. Nature and hydrocarbon content of the blooms of the alga Botryococcus braunii occurring in Australian fresh water lakes. Aust. J. Mar. Freshwater Res. 32: 353.
108. Wang, X. and Kolattukudy, P. E. 1995. Solubilization and purification of aldehyde generating fatty acyl-CoA reductase from green alga Botryococcus braunii. FEBS Lett. 370: 15.
109. Wang, X. and Xie, S. 1996. Effects of several factors on growth of Botryococcus braunii. Weishengwuxue Tongbao 23: 275.
110. Weetal, H. H. 1985. Studies on nutritional requirements of the oil producing alga Botryococcus braunii. Appl. Biochem. Biotechnol. 11: 377.
111. Weissman, J. C., Goebel, R. P., and Benemann, J. R. 1988. Photobioreactor design: mixing, carbon utilization, and oxygen accumulation. Biotechnol. Bioeng. 31: 336.
112. Wolf, F. R., Nanomura, A. M., and Bassham, J. A. 1985a. Growth and branched hydrocarbon production in a strain of Botryococcus braunii. J. Phycol. 21: 388.
113. Wolf, F. R., Nemethy, E. K., Blanding, J. H., and Bassham, J. A. 1985b. Biosynthesis of unusual acyclic isoprenoids in the green alga Botryococcus braunii. Phytochemistry 24: 733.
114. Yang, L. W. and Wang, X. Y. 1989. Studies on hydrocarbon production by immobilized Botryococcus braunii cells. Rev. Roum. Chim. 34: 397.
115. Yong, T. P. C., Largeau, C., and Casadevall, E. 1986. Biosynthesis of non-isoprenoid hydrocarbons by the microalga Botryococcus braunii. Evidences for elongation- decarboxylation mechanism. Nouv. J. Chim. 10: 701.
116. Zhang, D. and Poulter, C. D. 1995. Biosynthesis of non head to tail isoprenoid. Synthesis of 1′-1 and 1′-3 structures by recombinant yeast squalene synthase. J. Am. Chem. Soc. 117: 1641.
117. Zhang, K. and Kojima, E. 1998. Effect of light intensity on colony size of microalga Botryococcus braunii in bubble column photobioreactor. J. Fermentation Bioeng. 86: 573.