Antithyroid drug-induced immunomodulation in Graves' disease patients

Acta Medica Croatica

Volumn 56, Issue 1, 2002, Pages 21-26

  Lechpammer, Mirna ^a   Lukač, Josip ^a   Lechpammer, Stanislav ^a   Kusić, Zvonko ^a  

^a SESTRE MILOSRDNICE UNIVERSITY HOSPITAL   (Croatia)

Author keywords

Antithyroid agents therapeutic use; Graves' disease drug therapy; Graves' disease immunology; Thyroid disease drug therapy

Indexed keywords

ANTITHYROID AGENT; CARBIMAZOLE; PROPYLTHIOURACIL; THIAMAZOLE; THIONAMIDE;

ADULT; ARTICLE; CELLULAR IMMUNITY; FEMALE; GRAVES DISEASE; HORMONAL REGULATION; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; PHAGOCYTOSIS; THYROID DISEASE; THYROID FUNCTION; THYROID HORMONE BLOOD LEVEL;

ANTITHYROID AGENTS; FEMALE; GRAVES DISEASE; HUMANS; IMMUNITY, CELLULAR; IMMUNOSUPPRESSION; KILLER CELLS, NATURAL; LEUKOCYTE COUNT; MALE; METHIMAZOLE; MIDDLE AGED; PHAGOCYTOSIS;

EID: 0036404966     PISSN: 13300164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Cooper DS. Treatment of thyrotoxicosis. In: Braverman LE, Utiger RD, eds. Wemer and Ingbar's The Thyroid. A fundamental and clinical text. Philadelphia: JB Lippincott Company, 1991, 887.
2. Grebe SK, Feek CM, Ford HC et al. A randomized trial of short-term treatment of Graves' disease with high-dose carbimazole plus thyroxine versus low-dose carbimazole. Clin Endcrinol (Oxf.) 1998; 48: 585-92.
3. Mashio Y, Beniko M, Matsuda A et al. Treatment of hyperthyroidism with a small single daily dose of methimazole: A prospective long-term follow-up study. Endocrinol J 1997; 44: 553-8.
4. Bartalena L, Bogazzi F, Martino E. Adverse effects of thyroid hormone preparations and antithyroid drugs. Drug Saf 1996; 15: 53-63.
5. Bandyopadhyay U, Biswas K, Banerjee RK. Extrathyroidal actions of antithyroid thionamides. Toxicol Lett 2002; 128: 117-27.
6. Tajiri J, Noguchi S, Morita M, Tamaru M, Murakami N. Studies on onset patterns in antithyroid drug-induced agranulocytosis. Nippon Naibunpi Gakkai Zasshi 1993; 69: 530-3.
7. Dai WX, Zhang JD, Zhan SW et al. Retrospective analysis of 18 cases of antithyroid drug (ATD)-induced agranulocytosis. Endocrinol J 2002; 49: 29-33.
8. Ohashi H, Okugawa T, Itoh M. Circulating activated T cell subsets in autoimmune thyroid diseases, differences between untreated and treated patients. Acta Endocrinol (Copenh.) 1991; 125: 502-9.
9. Ludgate ME, McGregor AM, Weetman AP. Analysis of T cell subsets in Graves' disease: Alterations assodated with carbimazole. Br Med J (Clin Res) 1984; 288: 527-32.
10. Totterman TH, Karlsson FA, Bengtsson M, Mendel-Hartvig I. Induction of circulating activated suppressor-like T cells by methimazole therapy for Graves' disease. N Engl J Med 1987; 316: 15-21.
11. Wang PW, Luo SF, Huang BY, Lin JD, Huang MJ. Depressed natural killer activity in Graves' disease and during antithyroid medication. Clin Endocrinol 1988; 28: 205-14.
12. Pedersen BK, Feldt-Rasmusen U, Bech K, Perrild H, Karlnud K, Hoier-Madsen M. Characterization of the natural killer activity in Hashimoto's and Graves' diseases. Allergy 1989; 44: 477-81.
13. Rojano J, Sasian S, Gavilan I, Anguilar M, Escobar L, Giron JA. Serial analysis of the effects of methimazole or radical therapy on circulating CD16/56 subpopulations in Graves' disease. Eur J Endocrinol 1998; 139: 314-6.
14. Wenzel BE, Chow A, Baur R, Schleusener H, Wall JR. Natural killer cell activity in patients with Graves' disease and Hashimoto's thyoiditis. Thyroid 1998; 8: 1019-22.
15. Charreire J, Karsenty G, Bouchard P, Schaison G. Effect of carbimazole treatment on specific and non-specific immunological parameters in patients with Graves' disease. Clin Exp Immunol 1984; 57: 633-5.
16. Marazuela M, Vargas JA, Alvarez-Mon M, Albarran F, Lucas T, Durantez A. Impaired natural killer cytotoxicity in peripheral blood mononudear cells in Graves' disease. Eur J Endocrinol 1995; 132: 175-80.
17. Lukač J, Kusić Z, Kordić D, Končar M, Bolanča A. Natural killer cell activity, phagocytosis and number of peripheral blood cells in breast cancer patients treated with tamoxifen. Breast Cancer Res Treat 1994; 29: 279-85.
18. Pantazis CG, Kniker WT. Assessment of blood leukocyte microbial killing by using a new fluorochrome microassay. J Reticuloendothel Soc 1979; 26: 155-70.
19. Hrycek A, Kalina Z. Evaluation of the phagocytic activity of peripheral blood neutrophils in patients with hyperthyroidism. Endokrynol Pol 1989; 40: 15-24.
20. Lukač J, Kusič Z, Spaventi Š. Lymphocyte markers in Graves disease patients. Med Razgl 1988; 27: 51-4.