Analyses in transfected cells and in vitro of a putative peroxisomal targeting signal of rat liver serine:pyruvate aminotransferase

Histochemistry and Cell Biology

Volumn 118, Issue 4, 2002, Pages 321-328

  Mizuno, Takuji ^a   Ito, Kouichi ^a   Uchida, Chiharu ^a   Kitagawa, Masatoshi ^a   Ichiyama, Arata ^a   Miura, Satoshi ^b   Fujita, Kimio ^a   Oda, Toshiaki ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Organelle targeting; Peroxisomal targeting signal; Serine:pyruvate aminotransferase

Indexed keywords

ACYL COENZYME A OXIDASE; AMINOTRANSFERASE; MUTANT PROTEIN; SERINE; URATE OXIDASE; PRIMER DNA; SERINE PYRUVATE AMINOTRANSFERASE; SERINE-PYRUVATE AMINOTRANSFERASE; SIGNAL PEPTIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN COS1; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; GENETIC TRANSFECTION; IN VITRO STUDY; LIVER; MITOCHONDRION; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; RAT; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; POINT MUTATION; SITE DIRECTED MUTAGENESIS;

ANIMALIA;

ANIMALS; COS CELLS; DNA PRIMERS; IMMUNOHISTOCHEMISTRY; LIVER; MUTAGENESIS, SITE-DIRECTED; PEROXISOMES; POINT MUTATION; PROTEIN SORTING SIGNALS; TRANSAMINASES; TRANSFECTION;

EID: 0036401408     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-002-0455-6     Document Type: Article

References (25)

1. Conley EC, Saunders JR (1984) Recombination-dependent recircularization of linearized pBR322 plasmid DNA following transformation of Escherichia coli. Mol Gen Genet 194:211-218
2. Danpure CJ, Guttridge KM, Fryer P, Jennings PR, Allsop J, Purdue PE (1990) Subcellular distribution of hepatic alanine:glyoxylate aminotransferase in various mammalian species. J Cell Sci 97:669-678
3. Deng WP, Nickoloff JA (1992) Site-directed mutagenesis of virtually any plasmid by eliminating a unique site. Anal Biochem 200:81-88
4. Funai T, Ichiyama A (1995) Fidelity of translation initiation of mRNA for the precursor of rat mitochondrial serine:pyruvate/alanine:glyoxylate aminotransferase. J Biochem 117:1008-1016
5. Gould SJ, Keller GA, Hosken N, Wilkinson J, Subramani S (1989) A conserved tripeptide sorts proteins to peroxisomes. J Cell Biol 108:1657-1664
6. Higuchi R, Krummel B, Saiki K (1988) A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res 16:7351-7367
7. Leiper JM, Oatey PB, Danpure CJ (1996) Inhibition of alanine: glyoxylate aminotransferase 1 dimerization is a prerequisite for its peroxisome-to-mitochondrion mistargeting in primary hyperoxaluria type 1. J Cell Biol 135:939-951
8. McNew JA, Goodman JM (1996) The targeting and assembly of peroxisomal proteins: some old rules do not apply. Trends Biochem Sci 21:54-58
9. Miura S, Kasuya-Arai I, Mori H, Miyazawa S, Osumi T, Hashimoto T, Fujiki Y (1992) Carboxy-terminal consensus Ser-Lys-Leu-related tripeptide of peroxisomal proteins functions in vitro as a minimal peroxisome-targeting signal. J Biol Chem 267: 14405-14411
10. Mori M, Oda T, Nishiyama K, Serikawa T, Yamada J, Ichiyama A (1992) A single serine:pyruvate aminotransferase gene on rat chromosome 9q34-36. Genomics 13:686-689
11. Motley A, Lumb MJ, Oatey PB, Jennings PR, De Zoysa PA, Wanders RJA, Tabak HF, Danpure CJ (1995) Mammalian alanine:glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implication for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1. J Cell Biol 131:95-109
12. Noguchi T, Takada Y (1978) Peroxisomal localization of serine:pyruvate aminotransferase in human liver. J Biol Chem 253:7598-7600
13. Noguchi T, Minatogawa Y, Takada Y, Okuno E, Kido R (1978) Subcellular distribution of pyruvate (glyoxylate) aminotransferase in rat liver. Biochem J 170:173-175
14. Oda T, Ichiyama A, Miura S, Mori M, Tatibana M (1981) In vitro synthesis of a putative precursor of serine:pyruvate aminotransferase of rat liver mitochondria. Biochem Biophys Res Commun 102:568-573
15. Oda T, Yanagisawa M, Ichiyama A (1982) Induction of serine:pyruvate aminotransferase in rat liver organelles by glucagon and a high-protein diet. J Biochem 91:219-232
16. Oda T, Ichiyama A, Miura S, Mori M (1984) Uptake and processing of serine:pyruvate aminotransferase precursor by rat liver mitochondria in vitro and in vivo. J Biochem 95:815-824
17. Oda T, Miyajima H, Suzuki Y, Ichiyama A (1987) Nucleotide sequence of the cDNA encoding the precursor for mitochondrial serine:pyruvate aminotransferase of rat liver. Eur J Biochem 168:537-542
18. Oda T, Funai T, Ichiyama A (1990) Generation from a single gene of two mRNAs that encode the mitochondrial and peroxisomal serine:pyruvate aminotransferase of rat liver. J Biol Chem 265:7513-7519
19. Oda T, Funai T, Miura S (1996) In vitro association with peroxisomes and conformational change of peroxisomal serine:pyruvate/alanine:glyoxylate aminotransferase in rat and human livers. Biophys Biochem Res Commun 228:341-346
20. Oda T, Uchida C, Miura S (2000) Mitochondrial targeting signal-induced conformational change and repression of the peroxisomal targeting signal of the precursor for rat liver serine:pyruvate/alanine:glyoxylate aminotransferase. J Biochem 127:665-671
21. Osumi T, Tsukamoto T, Hata S, Yokota S, Miura S, Fujiki Y, Hijikata M, Miyazawa S, Hashimoto T (1991) Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting. Biochem Biophys Res Commun 181:947-954
22. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning. A laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp 16:30-16:36
23. Swinkels BW, Gould SJ, Bodnar AG, Rachubinski RA, Subramani S (1991) A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase. EMBO J 10:3255-3262
24. Takada Y, Noguchi T (1982) Subcellular distribution, and physical and immunological properties of hepatic alanine:glyoxylate aminotransferase isoenzymes in different mammalian species. Comp Biochem Physiol 72B:597-604
25. Yokota S, Funai T, Ichiyama A (1991) Organelle localization of rat liver serine:pyruvate aminotransferase expressed in transfected COS-1 cells. Biomed Res 12:53-59