Ruffini endings are absent from the periodontal ligament of trkB knockout mice

Somatosensory and Motor Research

Volumn 19, Issue 3, 2002, Pages 213-217

  Matsuo, Saburou ^a   Ichikawa, Hiroyuki ^a   Silos Santiago, Inmaculada ^a   Kiyomiya, Ken Ichi ^a   Kurebe, Masaru ^a   Arends, Joop J A ^a   Jacquin, Mark F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Immunohistochemistry; Incisor; Mechanoreceptor; Periodontal ligament; Ruffini endings; trkB

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALRETININ; GENE PRODUCT; NEUROTROPHIN RECEPTOR; PARVALBUMIN;

ANIMAL TISSUE; ARTICLE; IMMUNOHISTOCHEMISTRY; INNERVATION; KNOCKOUT MOUSE; MOUSE; NERVE ENDING; NONHUMAN; PERIODONTAL LIGAMENT; PRIORITY JOURNAL; TRIGEMINUS GANGLION;

ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; MECHANORECEPTORS; MICE; MICE, KNOCKOUT; NERVE ENDINGS; NERVE FIBERS; PERIODONTAL LIGAMENT; RECEPTOR, TRKA; RECEPTOR, TRKB; RECEPTOR, TRKC; THIOLESTER HYDROLASES; UBIQUITIN THIOLESTERASE;

EID: 0036397283     PISSN: 08990220     EISSN: None     Source Type: Journal    
DOI: 10.1080/0899022021000009134     Document Type: Article

References (26)

1. Biemesderfer, D., B.L. Munger, J. Binck, and R. Dubner (1978) The pilo-Ruffini complex: a non sinus hair and associated slowly-adapting mechanoreceptor in primate facial skin. Brain Res 142: 197-222.
2. Bothwell, M. (1995) Functional interactions of neurotrophins and neurotrophin receptors. Ann Rev Neurosci 18: 223-253.
3. Byers, M. (1985) Sensory innervation of periodontal ligament of rat molars consist of unencapsulated Ruffini-like mechanoreceptors and free nerve endings. J Comp Neural 231: 500-518.
4. Byers, M., and M.K. Dong (1989) Comparison of trigeminal receptor location and structure in the periodontal ligament of different types of teeth from the rat, cat and monkey. J Comp Neurol 279: 117-127.
5. Chambers, M., K.H. Anders, M. Von During, and M. Iggo (1972) The structure and function of the slowly adapting type II mechanoreceptor in hair skin. Q J Exp Physiol Cog Med Sci 57: 417-445.
6. Crowley, C., S.D. Spencer, M.C. Nishimura, K.S. Chen, S. Pitts-Meek, M.P. Armanini, L.H. Ling, S.B. McMahon, D.L. Shelton, A.D. Levinson, and S. Phillips (1994) Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76: 1001-1011.
7. Ernfors, P., K.-F. Lee, J. Kucera, and R. Jaenisch (1994) Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77: 503-512.
8. Fariñas, I., K.R. Jones, C. Backus, X.-Y. Wang, and F. Reichardt (1994) Severe sensory and sympathetic deficits in mice lacking neurotrophin-3. Nature 369: 658-661.
9. Fundin, B.T., I. Silos-Santiago, P. Ernfors, A.M. Fagan, H. Aldskogius, T.M. Dechiara, H.S. Phillips, M. Barbacid, G.D. Yancopoulos, and F.L. Rice (1997) Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. Dev Biol 190: 94-116.
10. Ichikawa, H., D.M. Jacobowitz, and T. Sugimoto (1997) Coexpression of calretinin and parvalbumin in Ruffini-like endings in the rat incisor periodontal ligament. Brain Res 770: 294-297.
11. Jones, K.R., I. Fariñas, C. Backus, and L.F. Reichardt (1994) Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76: 989-999.
12. Klein, R., I. Silos-Santiago, R.J. Smeyne, S.A. Lira, R. brambilla, S. Bryant, L. Zhang, and W.D. Snider (1994) Disruption of the neurotrophin-3 receptor gene trkC eliminates Ia muscle afferents and results in abnormal movements. Nature 368: 249-251.
13. Klein, R., R.J. Smeyne, W. Wurst, L.K. Long, B.A. Auerbach, A.L. Joyner, and M. Barbacid (1993) Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75: 113-122.
14. Kucera, J., G. Fan, J. Walro, S. Copray, L. Tessarollo, and R. Jaenish (1998) Neurotrophin-3 and trkC in muscle are non-essential for the development of mouse muscle spindle. Neuroreport 9: 905-909.
15. Lewin, G.R., and Y.-A. Barde (1996) Physiology of the neurotrophins. Ann Rev Neurosci 19: 289-317.
16. Lindsay, R.M., S.J. Wiegand, C.A. Aitar, and P.S. Distefano (1994) Neurotrophic factors: from molecules to man. Trends Neurosci 17: 182-190.
17. Matsuo, S., T.A. Henderson, T.M. Mosconi, I. Silos-Santiago, M. Barbacid, and M.F. Jacquin (1996) Oral somatosensory innervation in trkA, trkB, or trkC knockout mice. Soc Neurosci Abstr 22: 758.
18. Matsuo, S., H. Ichikawa, T.A. Henderson, I. Silos-Santiago, M. Barbacid, J.J.A. Arends, and M.F. Jacquin (2001) trkA modulation of developing somatosensory neurons in oro-facial tissues: tooth pulp fibers are absent in trkA knockout mice. Neuroscience 105: 747-760.
19. Matsuo, S., H. Ichikawa, I. Silos-santiago, J.J.A. Arends, T.A. Henderson, K. Kiyomiya, M. Kurebe, and M.F. Jacquin (2000) Proprioceptive afferents survive in the masseter muscle of trkC knockout mice. Neuroscience 95: 209-216.
20. Nakakura-Ohshima, K., T. Maeda, H. Ohshima, T. Noda, and Y. Takano (1995) Postnatal development of peripheral Ruffini endings in rat incisor: an immunoelectron microscopic study using protein gene product 9.5 (PGP 9.5) antibody. J Comp Neurol 362: 551-564.
21. Ochi, K., S. Wakisaka, S.H. Youn, K. Hanada, and T. Maeda (1997) Calretinin-like immunoreactivity in the Ruffini endings, slowly adapting mechanoreceptors, of the periodontal ligament of the rat incisor. Brain Res 769: 183-187.
22. Sato, O., T. Maeda, S. Kobayashi, T. Wanaga, T. Fujita, and Y. Takahashi (1988) Innervation of periodontal ligament and dental pulp in the rat incisor: an immunohistochemical investigation of neurofilament protein and glia-specific S-100 protein. Cell Tissue Res 25: 13-21.
23. Segal, R.A., and M.E. Greenberg (1996) Intracellular signaling pathways activated by neurotrophic factors. Ann Rev Neurosci 19: 463-489.
24. Smeyne, R.J., R. Klein, A. Schnapp, L.K. Long, S. Bryant, A. Lewin, S.A. Lira, and M. Barbacid (1994) Severe sensory and sympathetic neuropathies in mice carrying a disrupted trk/NGF receptor gene. Nature 368: 246-249.
25. Snider, W.D. (1994) Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 76: 627-638.
26. Tessarollo, L., K.S. Vogel, M.E. Palko, S.W. Reid, and L.F. Parada (1994) Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons. Proc Natl Acad Sci USA 91: 11844-11848.