Phagocytosis by emigrated, intra-abdominal neutrophils is depressed during human secondary peritonitis

European Surgical Research

Volumn 34, Issue 4, 2002, Pages 275-284

  Holzer, Katharina ^a   Konietzny, P ^a   Wilhelm, Kerstin ^a   Encke, A ^a   Henrich, D ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

CD11 CD18; CD16; CD32; CD64; Complement receptors; Emigration; Fc receptors; Neutrophils; Peritonitis; Phagocytosis; PMNs

Indexed keywords

CD16 ANTIGEN; CD18 ANTIGEN; CD32 ANTIGEN; CD64 ANTIGEN; COMPLEMENT COMPONENT C3B RECEPTOR; FC RECEPTOR; RECEPTOR SUBUNIT;

ABDOMINAL SURGERY; ARTICLE; BACTERIAL PERITONITIS; CELL FUNCTION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ESCHERICHIA COLI; FLUORESCENCE; HUMAN; HUMAN CELL; MULTIPLE ORGAN FAILURE; NEUTROPHIL; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPTIC SHOCK;

ABDOMINAL CAVITY; ANTIGENS, CD18; CELL MOVEMENT; CELL SURVIVAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMANS; MULTIPLE ORGAN FAILURE; NEUTROPHILS; PERITONITIS; PHAGOCYTOSIS; RECEPTORS, COMPLEMENT; RECEPTORS, COMPLEMENT 3B; RECEPTORS, IGG; SHOCK, SEPTIC; TEMPERATURE;

EID: 0036392072     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000063071     Document Type: Article

References (19)

1. Vincent J-L, de Mendonca A, Cantraine F, et al: Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study. Crit Care Med 1998;26:1793-1800.
2. van Goor H, Hulsebos RG, Bleichrodt RP: Complications of planned relaparotomy in patients with severe general peritonitis. Eur J Surg 1997;163:61-66.
3. Seiler CA, Brügger L, Forssmann U, Baer HU, Büchler MW: Conservative surgical treatment of diffuse peritonitis. Surgery 2000;127:178-184.
4. Koperna T, Schulz F: Prognosis and treatment of peritonitis: Do we need new scoring systems? Arch Surg 1996;131:180-186.
5. Edmiston CE, Goheen MP, Kornhall S, Jones FE, Condon RE: Fecal peritonitis: Microbial adherence to serosal mesothelium and resistance to peritoneal lavage. World J Surg 1990;14:176-183.
6. Freischlag J, Backstrom B, Kelly D, Keehn G, Busuttil RW: Comparison of blood and peritoneal neutrophil activity in rabbits with and without peritonitis. J Surg Res 1986;40:145-151.
7. Palmer MA, Bornside GH, Nance FC: Sepsis-induced depression of phagocytosis in experimental canine peritonitis. Am Surg 1982;48:520-524.
8. Ahmed NA, McGill S, Yee J, Hu F, Michel RP, Christou NV: Mechanisms for the diminished neutrophil exudation to secondary inflammatory sites in infected patients with a systemic inflammatory response (sepsis). Crit Care Med 1999;27:2459-2468.
9. Burger JA, Schöffel U, Sach M, Jakobs E, Kownatzki E, v. Specht BU, Farthmann EH: Effects of peritonitis exudates on chemotaxis and phagocytosis of human neutrophils. Eur J Surg 1995;161:647-653.
10. Lam C, Schulz F, Laber G, Schütze E: Opsonic activity of the alternative complement pathway in infected human intra-abdominal fluid. Infection 1985;13:8-12.
11. Schutze GE, Hall MA, Baker CJ, Edwards MS: Role of neutrophil receptors in opsonophagocytosis of coagulase-negative staphylococci. Infect Immun 1991;59:2573-2578.
12. Anderson CL, Shen L, Eicher DM, Wewers MD, Gill JK: Phagocytosis mediated by three distinct Fcy receptor classes on human leukocytes. J Exp Med 1990;171:1333-1345.
13. Dransfield I, Buckle A-M, Savill JS, McDowall A, Haslett C, Hogg N: Neutrophil apoptosis is associated with a reduction in CD16 (FcyRIII) expression. J Immunol 1994;153:1254-1263.
14. Mahidhara R, Billiar TR: Apoptosis in sepsis. Crit Care Med 2000;28(suppl):N105-N113.
15. Schöffel U, Jacobs E, Ruf G, Mierswa F, v Specht BU, Farthmann EH: Intraperitoneal micro-organisms and the severity of peritonitis. Eur J Surg 1995;161:501-508.
16. Holzer K, Richter A, Henrich D, Wilhelm K, Encke A: Oxygen radical production of emigrated and circulating polymorphonuclear leukocytes during secondary peritonitis; in Faist E (ed): 5th World Congress on Trauma, Shock, Inflammation and Sepsis Pathophysiology, Immune Consequences and Therapy. Bologna, Monduzzi Editore, 2000, pp 593-597.
17. Rosenbloom AJ, Pinsky MR, Napolitano C, Nguyen, T-S, Levann D, Pencosky N, Dorrance A, Ray BK, Whiteside T: Suppression of cytokine-mediated β2-integrin activation on circulating neutrophils in critically ill patients. J Leukoc Biol 1999;65:83-89.
18. Schleiffenbaum B, Moser R, Patarroyo M, Fehr J: The cell surface glycoprotein Mac-1 (CD11/CD18) mediates neurtrophil adhesion and modulates degranulation independently of its quantitative cell surface expression. J Immunol 1989;142:3537-3545.
19. Holzer K, Richter A, Henrich D, Wilhelm K, Encke A: Oxygen radical generation by emigrated, intra-abdominal and circulating PMNLs during secondary peritonitis. Shock 2001;15;90-94.