메뉴 건너뛰기




Volumn 23, Issue 1-3, 2002, Pages 273-281

Topical application of dynorphin A (1-17) antiserum attenuates trauma induced alterations in spinal cord evoked potentials, microvascular permeability disturbances, edema formation and cell injury: An experimental study in the rat using electrophysiological and morphological approaches

Author keywords

Amino acids; Dynorphin antiserum; Edema; Spinal cord evoked potentials; Spinal cord injury; Ultrastructure

Indexed keywords

DYNORPHIN A; DYNORPHIN ANTIBODY;

EID: 0036392024     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-001-0138-y     Document Type: Conference Paper
Times cited : (40)

References (42)
  • 1
    • 0020074811 scopus 로고
    • Opiate antagonists improve survival in anaphylacic shock
    • Amir S (1982) Opiate antagonists improve survival in anaphylacic shock. Eur J Pharmacol 80: 161-162
    • (1982) Eur J Pharmacol , vol.80 , pp. 161-162
    • Amir, S.1
  • 4
    • 0022592355 scopus 로고
    • Plasma extravasation induced by dynorphin (1-13) in rat skin
    • Chahl LA, Chahl JS (1986) Plasma extravasation induced by dynorphin (1-13) in rat skin. Eur J Pharmacol 124: 343-347
    • (1986) Eur J Pharmacol , vol.124 , pp. 343-347
    • Chahl, L.A.1    Chahl, J.S.2
  • 5
    • 0345158331 scopus 로고
    • Specific receptors for the opiod peptide dynorphin: Structure activity relationships
    • Chavkin C, Goldstein A (1981) Specific receptors for the opiod peptide dynorphin: structure activity relationships. Proc Natl Acad Sci USA 78: 6543-6548
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 6543-6548
    • Chavkin, C.1    Goldstein, A.2
  • 6
    • 0024598095 scopus 로고
    • Ultrastructural analysis of dynorphin B-immunoreactive cells and terminals in the superficial dorsal horn of the deafferented spinal cord of the rat
    • Cho HJ, Basbaum AI (1989) Ultrastructural analysis of dynorphin B-immunoreactive cells and terminals in the superficial dorsal horn of the deafferented spinal cord of the rat. J Comp Neurol 281: 193-201
    • (1989) J Comp Neurol , vol.281 , pp. 193-201
    • Cho, H.J.1    Basbaum, A.I.2
  • 7
    • 0028949109 scopus 로고
    • The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat
    • Chen L, Gu Y, Huang L-YM (1995) The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat. J Physiol (London) 482: 575-581
    • (1995) J Physiol (London) , vol.482 , pp. 575-581
    • Chen, L.1    Gu, Y.2    Huang, L.-Y.M.3
  • 8
    • 0000602674 scopus 로고
    • Opioids and sensory processing in the central nervous system
    • Duggan AW, Fleetwood-Walker SM (1993) Opioids and sensory processing in the central nervous system. Handbook Exp Pharmacol 104 (II): 731-771
    • (1993) Handbook Exp Pharmacol , vol.104 , Issue.2 , pp. 731-771
    • Duggan, A.W.1    Fleetwood-Walker, S.M.2
  • 10
    • 0025038060 scopus 로고
    • Opioid and non-opioid mechanisms may contribute to dynorphin's pathophysiological actions in the spinal cord injury
    • Faden AI (1990) Opioid and non-opioid mechanisms may contribute to dynorphin's pathophysiological actions in the spinal cord injury. Ann Neurol 27: 64-74
    • (1990) Ann Neurol , vol.27 , pp. 64-74
    • Faden, A.I.1
  • 11
    • 0001020147 scopus 로고
    • Role of endogenous opioids and opioid receptors in central nervous system injury
    • Faden AI (1993) Role of endogenous opioids and opioid receptors in central nervous system injury. Handbook Exp Pharmacol 104 Part I: 325-341
    • (1993) Handbook Exp Pharmacol , vol.104 , Issue.PART I , pp. 325-341
    • Faden, A.I.1
  • 12
    • 0029681401 scopus 로고    scopus 로고
    • Neurotoxic versus neuroprotective actions of endogenous opioid peptides: Implications for treatment of CNS injury
    • Faden AI (1996) Neurotoxic versus neuroprotective actions of endogenous opioid peptides: Implications for treatment of CNS injury. NIDA Res Mongr 163: 318-330
    • (1996) NIDA Res Mongr , vol.163 , pp. 318-330
    • Faden, A.I.1
  • 13
    • 0023597416 scopus 로고
    • Kappa-selective opiate antagonist norbinaltorphine improves outcome after traumatic spinal cord injury in rats
    • Faden AI, Takemori AE, Portoghese PS (1987) Kappa-selective opiate antagonist norbinaltorphine improves outcome after traumatic spinal cord injury in rats. Cent Nerv Syst Trauma 4: 227-237
    • (1987) Cent Nerv Syst Trauma , vol.4 , pp. 227-237
    • Faden, A.I.1    Takemori, A.E.2    Portoghese, P.S.3
  • 15
    • 0023893404 scopus 로고
    • The influence of opioid receptor subtypes on the processing of nociceptive inputs in the spinal dorsal horn of the cat
    • Fleetwood-Walker SM, Hope PJ, Mitchell R, El-Yassir N, Molony V (1988) The influence of opioid receptor subtypes on the processing of nociceptive inputs in the spinal dorsal horn of the cat. Brain Res 451: 213-226
    • (1988) Brain Res , vol.451 , pp. 213-226
    • Fleetwood-Walker, S.M.1    Hope, P.J.2    Mitchell, R.3    El-Yassir, N.4    Molony, V.5
  • 16
    • 0025687709 scopus 로고
    • Intrathecal somatostatin analogs, substance P analog and dynorphin A cause comparable neurotoxicity in rats
    • Gaumann DM, Grabow TS, Yaksh TL, Casy SJ, Rodriguez M (1990) Intrathecal somatostatin analogs, substance P analog and dynorphin A cause comparable neurotoxicity in rats. Neuropharmacology 39: 761-774
    • (1990) Neuropharmacology , vol.39 , pp. 761-774
    • Gaumann, D.M.1    Grabow, T.S.2    Yaksh, T.L.3    Casy, S.J.4    Rodriguez, M.5
  • 17
    • 0021141729 scopus 로고
    • Dynorphin: Important mediator for electroacupuncture analgesia in the spinal cord of the rabbit
    • Han J, Xie G (1984) Dynorphin: important mediator for electroacupuncture analgesia in the spinal cord of the rabbit. Pain 18: 367-376
    • (1984) Pain , vol.18 , pp. 367-376
    • Han, J.1    Xie, G.2
  • 18
    • 0035120270 scopus 로고    scopus 로고
    • Structure-activity analysis of dynorphin A toxicity in spinal cord neurons: Intrinsic neurotoxicity of dynorphin A and its carboxyl-terminal, nonopioid metabolites
    • Hauser KF, Knapp PE, Turbek CS (2001) Structure-activity analysis of dynorphin A toxicity in spinal cord neurons: Intrinsic neurotoxicity of dynorphin A and its carboxyl-terminal, nonopioid metabolites. Exp Neurol 168: 78-87
    • (2001) Exp Neurol , vol.168 , pp. 78-87
    • Hauser, K.F.1    Knapp, P.E.2    Turbek, C.S.3
  • 20
    • 0025106954 scopus 로고
    • MK-801 blocks dynorphin A (1-13)-induced loss of the tail flick reflex in the rat
    • Isaac L, O'Malley TVZ, Ristic H, Stewart P (1990) MK-801 blocks dynorphin A (1-13)-induced loss of the tail flick reflex in the rat. Brain Res 531: 83-87
    • (1990) Brain Res , vol.531 , pp. 83-87
    • Isaac, L.1    O'Malley, T.V.Z.2    Ristic, H.3    Stewart, P.4
  • 21
    • 0024268743 scopus 로고
    • Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: Stimulus specificity, behavioural parameters and opioid receptor binding
    • Iadarola MJ, Brady LS, Draisci G, Dubner R (1988) Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: Stimulus specificity, behavioural parameters and opioid receptor binding. Pain 35: 313-326
    • (1988) Pain , vol.35 , pp. 313-326
    • Iadarola, M.J.1    Brady, L.S.2    Draisci, G.3    Dubner, R.4
  • 22
    • 0023735298 scopus 로고
    • Hindlimb paralytic effects of prodynorphin-derived peptides following spinal subarachnoid injection in rats
    • Long JB, Martinez-Arizala A, Echevarria EE, Tidwell RE, Holaday JW (1988) Hindlimb paralytic effects of prodynorphin-derived peptides follwoing spinal subarachnoid injection in rats. Eur J Pharmacol 153: 45-54
    • (1988) Eur J Pharmacol , vol.153 , pp. 45-54
    • Long, J.B.1    Martinez-Arizala, A.2    Echevarria, E.E.3    Tidwell, R.E.4    Holaday, J.W.5
  • 23
    • 0024420925 scopus 로고
    • Dynorphin A-induced rat hindlimb paralysis and spinal cord injury are not altered by the κ-opioid antagonist norbinaltorphimine
    • Long JB, Rigamonti DR, deCosta B, Rice KC, Martinez-Arizala A (1989) Dynorphin A-induced rat hindlimb paralysis and spinal cord injury are not altered by the κ-opioid antagonist norbinaltorphimine. Brain Res 497: 155-162
    • (1989) Brain Res , vol.497 , pp. 155-162
    • Long, J.B.1    Rigamonti, D.R.2    DeCosta, B.3    Rice, K.C.4    Martinez-Arizala, A.5
  • 24
    • 0028344182 scopus 로고
    • Dynorphin A-induced rat spinal cord injury: Evidence for excitatory amino acid involvement in a pharmacological model of spinal cord injury
    • Long JB, Rigamonti DD, Oleshansky MA, Wingfield CP, Martinez-Arizala A (1994) Dynorphin A-induced rat spinal cord injury: evidence for excitatory amino acid involvement in a pharmacological model of spinal cord injury. J Pharmacol Exp Ther 296: 358-366
    • (1994) J Pharmacol Exp Ther , vol.296 , pp. 358-366
    • Long, J.B.1    Rigamonti, D.D.2    Oleshansky, M.A.3    Wingfield, C.P.4    Martinez-Arizala, A.5
  • 25
    • 0031031960 scopus 로고    scopus 로고
    • Enhancement of the antiallodynic and antinociceptive efficacy of spinal morphin by antisera to dynorphin A (1-13) or MK-801 in nerve-ligation model of peripheral neuropathy
    • Nichols ML, Lopez Y, Ossipov MH, Bian D, Porreca F (1997) Enhancement of the antiallodynic and antinociceptive efficacy of spinal morphin by antisera to dynorphin A (1-13) or MK-801 in nerve-ligation model of peripheral neuropathy. Pain 69: 317-322
    • (1997) Pain , vol.69 , pp. 317-322
    • Nichols, M.L.1    Lopez, Y.2    Ossipov, M.H.3    Bian, D.4    Porreca, F.5
  • 26
    • 0000751786 scopus 로고
    • Opioid actions on membrane ion channels
    • North RA (1993) Opioid actions on membrane ion channels. Handbook Exp Pharmacol 104 (II): 773-797
    • (1993) Handbook Exp Pharmacol , vol.104 , Issue.2 , pp. 773-797
    • North, R.A.1
  • 28
    • 0023065278 scopus 로고
    • Effect of captopril (a converting enzyme inhibitor) on blood-brain barrier permeability and cerebral bloodflow in normotensive rats
    • Sharma HS (1987) Effect of captopril (a converting enzyme inhibitor) on blood-brain barrier permeability and cerebral bloodflow in normotensive rats. Neuropharmacology 26: 85-92
    • (1987) Neuropharmacology , vol.26 , pp. 85-92
    • Sharma, H.S.1
  • 29
    • 0001906964 scopus 로고    scopus 로고
    • Pathophysiology of blood-brain barrier, brain edema and cell injury following hyperthermia: New role of heat shock protein, nitric oxide and carbon monoxide. An experimental study in the rat using light and electron microscopy
    • Sharma HS (1999) Pathophysiology of blood-brain barrier, brain edema and cell injury following hyperthermia: new role of heat shock protein, nitric oxide and carbon monoxide. An experimental study in the rat using light and electron microscopy. Acta Universitatis Upsaliensis 830: 1-94
    • (1999) Acta Universitatis Upsaliensis , vol.830 , pp. 1-94
    • Sharma, H.S.1
  • 30
    • 0025370773 scopus 로고
    • Edema formation and cellular alterations following spinal cord injury in rat and their modification with p-chlorophenylalanine
    • Sharma HS, Olsson Y (1990) Edema formation and cellular alterations following spinal cord injury in rat and their modification with p-chlorophenylalanine. Acta Neuropathologica (Berlin) 79: 604-610
    • (1990) Acta Neuropathologica (Berlin) , vol.79 , pp. 604-610
    • Sharma, H.S.1    Olsson, Y.2
  • 31
    • 0025827968 scopus 로고
    • Evaluation of traumatic spinal cord edema using evoked potentials recorded from the spinal epidural space. An experimental study in the rat
    • Sharma HS, Winkler T, Stålberg E, Olsson Y, Dey PK (1991) Evaluation of traumatic spinal cord edema using evoked potentials recorded from the spinal epidural space. An experimental study in the rat. J Neurol Sci 102: 150-162
    • (1991) J Neurol Sci , vol.102 , pp. 150-162
    • Sharma, H.S.1    Winkler, T.2    Stålberg, E.3    Olsson, Y.4    Dey, P.K.5
  • 32
    • 0026620845 scopus 로고
    • Dynorphin A content in the rat brain and spinal cord after a localized trauma to the spinal cord and its modification with p-chlorophenylalanine. An experimental study using radioimmunoassay technique
    • Sharma HS, Nyberg F, Olsson Y (1992) Dynorphin A content in the rat brain and spinal cord after a localized trauma to the spinal cord and its modification with p-chlorophenylalanine. An experimental study using radioimmunoassay technique. Neuroscience Research 14: 195-203
    • (1992) Neuroscience Research , vol.14 , pp. 195-203
    • Sharma, H.S.1    Nyberg, F.2    Olsson, Y.3
  • 33
    • 0028582257 scopus 로고
    • Influence of dynorphin-A antibodies on the formation of edema and cell changes in spinal cord trauma
    • Sharma HS, Olsson Y, Nyberg F (1995) Influence of dynorphin-A antibodies on the formation of edema and cell changes in spinal cord trauma. Prog Brain Res 104: 401-416
    • (1995) Prog Brain Res , vol.104 , pp. 401-416
    • Sharma, H.S.1    Olsson, Y.2    Nyberg, F.3
  • 34
    • 0036392023 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors influence dynorphin A (1-17) immunoreactivity in the rat brain following hyperthermia
    • Sharma HS, Alm P (2002) Nitric oxide synthase inhibitors influence dynorphin A (1-17) immunoreactivity in the rat brain following hyperthermia. Amino Acids 23: 247-259
    • (2002) Amino Acids , vol.23 , pp. 247-259
    • Sharma, H.S.1    Alm, P.2
  • 35
    • 0036263422 scopus 로고    scopus 로고
    • Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials. A pharmacological and morphological study in the rat
    • in press
    • Sharma HS, Winkler T (2002) Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials. A pharmacological and morphological study in the rat. Muscle and Nerve (in press)
    • (2002) Muscle and Nerve
    • Sharma, H.S.1    Winkler, T.2
  • 38
    • 0021962503 scopus 로고
    • The histamine releasing effect of dynorphin and other opioid peptides possessing arg-pro sequences
    • Sydbom A, Terenius L (1985) The histamine releasing effect of dynorphin and other opioid peptides possessing arg-pro sequences. Agents Actions 16: 269-272
    • (1985) Agents Actions , vol.16 , pp. 269-272
    • Sydbom, A.1    Terenius, L.2
  • 39
    • 0034128003 scopus 로고    scopus 로고
    • Dynorphin A elicits an increase in intracellular calcium in cultured neurons via a non-opioid, non-NMDA mechanims
    • Tang Q, Lynch RM, Porreca F, Lai J (2000) Dynorphin A elicits an increase in intracellular calcium in cultured neurons via a non-opioid, non-NMDA mechanims. J Neurophysiol 83: 2610-2615
    • (2000) J Neurophysiol , vol.83 , pp. 2610-2615
    • Tang, Q.1    Lynch, R.M.2    Porreca, F.3    Lai, J.4
  • 40
    • 0027447711 scopus 로고
    • The opioid peptide dynorphin mediates hetrosynaptic depression of hippocampalmossy fibre synapses and modulates long-term potentialtion
    • Weisskopf MG, Zalutsky RA, Nicoll RA (1993) The opioid peptide dynorphin mediates hetrosynaptic depression of hippocampalmossy fibre synapses and modulates long-term potentialtion. Nature 362: 423-427
    • (1993) Nature , vol.362 , pp. 423-427
    • Weisskopf, M.G.1    Zalutsky, R.A.2    Nicoll, R.A.3
  • 41
    • 0028597549 scopus 로고
    • Opioid receptors influence spinal cord electrical activity and edema formation following spinal cord injury. Experimental observations using naloxone in the rat
    • Winkler T, Sharma HS, Stålberg E, Olsson Y, Nyberg F (1994) Opioid receptors influence spinal cord electrical activity and edema formation following spinal cord injury. Experimental observations using naloxone in the rat. Neurosci Res 21: 91-101
    • (1994) Neurosci Res , vol.21 , pp. 91-101
    • Winkler, T.1    Sharma, H.S.2    Stålberg, E.3    Olsson, Y.4    Nyberg, F.5
  • 42
    • 0001811409 scopus 로고    scopus 로고
    • Spinal cord bioelectrical activity, edema and cell injury following a focal trauma to the spinal cord. An experimental study using pharmacological and morphological approach
    • Stålberg E, Sharma HS, Olsson Y (eds), Springer, Wien New York
    • Winkler T, Sharma HS, Stålberg E, Westman J (1998) Spinal cord bioelectrical activity, edema and cell injury following a focal trauma to the spinal cord. An experimental study using pharmacological and morphological approach. In: Stålberg E, Sharma HS, Olsson Y (eds) Spinal cord monitoring, Springer, Wien New York, pp 281-348
    • (1998) Spinal Cord Monitoring , pp. 281-348
    • Winkler, T.1    Sharma, H.S.2    Stålberg, E.3    Westman, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.