Inhibition of cGMP-dependent protein kinases potently decreases neutrophil spontaneous apoptosis

Biochemical and Biophysical Research Communications

Volumn 297, Issue 3, 2002, Pages 498-501

  Brunetti, Mauro ^a,b   Mascetra, Nicola ^a   Manarini, Stefano ^a   Martelli, Nicola ^a   Cerletti, Chiara ^a   Musiani, Piero ^b   Aiello, Francesca B ^a,b   Evangelista, Virgilio ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

Apoptosis; cGMP dependent protein kinases; Neutrophils; Signal transduction

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; 4 [[3',4' (METHYLENEDIOXY)BENZYL]AMINO] 6 METHOXYQUINAZOLINE; CYCLIC GMP; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GUANYLATE CYCLASE ACTIVATOR; KT 5823; LIPOPOLYSACCHARIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHODIESTERASE INHIBITOR; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL;

ALKALOIDS; APOPTOSIS; CARBAZOLES; CELLS, CULTURED; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; HUMANS; INDOLES; ISOQUINOLINES; KINETICS; NEUTROPHILS; PHOSPHODIESTERASE INHIBITORS; SULFONAMIDES;

EID: 0036387180     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02246-5     Document Type: Article

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