Evaluation of solid dispersions of clofazimine

Drug Development and Industrial Pharmacy

Volumn 28, Issue 8, 2002, Pages 1001-1013

  Narang, Ajit S ^a   Srivastava, Anand K ^b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

Clofazimine; Dissolution; Solid dispersions

Indexed keywords

CLOFAZIMINE; DRUG CARRIER; GELATIN; HYDROCHLORIC ACID; MACROGOL; POVIDONE; SOLVENT; LEPROSTATIC AGENT; MACROGOL DERIVATIVE; MUSCARINIC RECEPTOR BLOCKING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

ARTICLE; CRYSTALLIZATION; DISPERSION; DRUG EFFECT; DRUG FORMULATION; DRUG MARKETING; DRUG MIXTURE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; LIQUID; MOLECULAR WEIGHT; PARTICLE SIZE; SOLID; X RAY DIFFRACTION; CHEMISTRY; COMPARATIVE STUDY; HUMAN; INFRARED SPECTROPHOTOMETRY; SOLUBILITY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; CLOFAZIMINE; DRUG COMPOUNDING; DRUG STABILITY; HUMANS; LEPROSTATIC AGENTS; MOLECULAR WEIGHT; MUSCARINIC ANTAGONISTS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POVIDONE; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; X-RAY DIFFRACTION;

EID: 0036386054     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-120006431     Document Type: Article

References (16)

1. Martindale: The Extra Pharmacopoeia, 29th Ed.; Reynolds, J.E.F., Ed.; The Pharmaceutical Press: London, 1989; 556-557.
2. Rang, H.P.; Dale, M.M.; Ritter, J.M. In Pharmacology, 3rd Ed.; Churchill Livingstone: New York, 1995; 741-743.
3. Harvey, C.H. Anti Microbial Drugs. In Remington's Pharmaceutical Sciences, 18th Ed.; Gennaro, A.R., Ed.; Mack Publishing Company: Pennsylvania, 1970; 1223.
4. Hooper, M.; Purohit, M.G. The Chemotherapy of Leprosy. In Ellis, P.G., West, B.G., Eds.; Progr. Med. Chem. 1983, 20, 1-81.
5. Krishnan, T.R.; Abraham, I. Drug Dev. Ind. Pharm. 1991, 17, 1823-1842.
6. Krishnan, T.R.; Abraham, I. Biopharm. Drug Dispos. 1994, 15, 329-339.
7. Yawalkar, S.J.; Vischer, W. Lep. Rev. 1979, 50, 135-144.
8. Barnerjee, D.K.; Ellard, G.A.; Gammon, P.T.; Waters, M.R.F. Am. J. Trop. Med. Hyg. 1974, 23, 1110-1115.
9. Holdiness, M.R. Clin. Pharmacokinet. 1989, 16, 74-85.
10. Orange Book, U.S. FDA (http://www.fda.gov/cder/ ob).
11. Dordunoo, S.K.; Ford, J.L.; Rubinstein, M.H. Drug Dev. Ind. Pharm. 1991, 17, 1685-1713.
12. Pavia, D.L.; Lapman, G.M.; Kriz, G.S. In Introduction to Spectroscopy, 1st Ed.; Saunders College Publishing: USA, 1979; 13-27.
13. Martin, A. In Physical Pharmacy, 3rd Ed.; Waverly Intl.: USA, 1993; 236-237, 330-332.
14. Rosmesen, I. Acta Dermatol. Vener. 1983, 63, 552-565.
15. De Taeye, J.; Zeegers-Huyskens, T. J. Pharm. Sci. 1985, 74, 660-663.
16. Simonelli, A.P.; Meshali, M.M.; Abd El-Gawad, A.H.; Abdel-Aleem, H.M.; Gabr, K.E. Drug Dev. Ind. Pharm. 1994, 20, 2741-2752.