Thyroid hormone augmentation with levothyroxine in bipolar depression

Bipolar Disorders

Volumn 4, Issue SUPPL. 1, 2002, Pages 109-110

  Bauer, Michael ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; FLUORODEOXYGLUCOSE F 18; GLUCOSE; LEVOTHYROXINE; LITHIUM; PLACEBO; THYROID HORMONE; THYROXINE;

ADD ON THERAPY; AMYGDALOID NUCLEUS; ARTICLE; BIPOLAR DEPRESSION; BRAIN CORTEX; BRAIN FUNCTION; BRAIN METABOLISM; BRAIN STEM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE COURSE; DRUG EFFICACY; DRUG SAFETY; FREE THYROXINE INDEX; GLUCOSE METABOLISM; HIPPOCAMPUS; HUMAN; MOOD; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REMISSION; SUBICULUM; THALAMUS; THYROID FUNCTION;

BIPOLAR DISORDER; CEREBRAL CORTEX; FLUORODEOXYGLUCOSE F18; GLUCOSE; HUMANS; PSYCHIATRIC STATUS RATING SCALES; THYROID HORMONES; THYROXINE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036382205     PISSN: 13985647     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-5618.4.s1.59.x     Document Type: Article

References (9)

1. Müller-Oerlinghausen Berghöfer A, Bauer M. Bipolar disorder. Lancet 2002; 359: 241-247.
2. Bauer M, Whybrow PC. Thyroid hormone, neural tissue and mood modulation. World J Biol Psychiatr 2001; 2: 57-67.
3. Frye MA, Denicoff KD, Bryan AL et al. Association between lower serum free T4 and greater mood instability and depression in lithium-maintained bipolar patients. Am J Psychiatry 1999; 156: 1909-1914.
4. Cole DP, Thase ME, Mallinger AG et al. Slower treatment response in bipolar depression predicted by lower pretreatment thyroid function. Am J Psychiatry 2002; 159: 116-121.
5. Bauer MS, Whybrow PC. Rapid cycling bipolar affective disorder. II. Treatment of refractory rapid cycling with high-dose levothyroxine: a preliminary study. Arch General Psychiatr 1990; 47: 435-440.
6. Bauer M, Priebe S, Berghöfer A, Bschor T, Kiesslinger K, Whybrow PC. Subjective response to and tolerability of long-term supraphysiological doses of levothyroxine in refractory mood disorders. J Affect Disord 2001; 64: 35-42.
7. Bauer M, Berghöfer A, Bschor T et al. Supraphysiological doses of 1-thyroxine in the maintenance treatment of prophylaxis-resistant affective disorders. Neuropsychopharmacology 2002; (in press).
8. Bauer M, Hellweg R, Gräf KJ, Baumgartner A. Treatment of refractory depression with high-dose thyroxine. Neuropsychopharmacology 1998; 18: 444-455.
9. Bauer M, London E, Rasgon N et al. effects of supraphysiological doses of 1-thyroxine on regional brain metabolism in bipolar disorder: results of a FDG-PET study. American College of Neuropsychopharmacology (ACNP) 40th Annual Meeting, Hawaii, 2001.