Selective damage of pigmented cells by means of a rapidly scanned cw laser beam

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 4617, Issue , 2002, Pages 134-140

  Brinkmann, Ralf ^a   Koop, Norbert ^a   Özdemir, Mustafa ^a   Alt, Clemens ^a   Schüle, Georg ^a   Lin, Charles P ^a   Birngruber, Reginald ^a  

^a MEDICAL LASER CENTER LÜBECK   (Germany)

Author keywords

Fluorescence microscopy; Laser scanner; Melanosome; RPE; Selective photocoagulation; Viability assay

Indexed keywords

ANGIOGRAPHY; CELLS; FLUORESCENCE; LASER PULSES; PIGMENTS; TISSUE;

PIGMENTED CELLS;

LASER DAMAGE;

EID: 0036381272     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.472538     Document Type: Conference Paper

References (14)

1. R. R. Anderson and J. A. Parrish, "Selective Photothermolysis: Precise Microsurgery by Selective Absorption of Pulsed Laser Radiation", Science 220, pp. 524-527, 1983.
2. J. A. Parrish, R. R. Anderson, T. Harrist, B. Paul, and G. F. Murphy, "Selective Thermal Effects with Pulsed Irradiation from Lasers: From Organ to Organelle", J. Invest. Derm. 80, pp. 75-80, 1983.
3. M. A. Latina and C. Park, "Selective Targeting of Trabecular Meshwork cells: In Vitro Studies of Pulsed and CW Laser Interaction", Exp. Eye Res. 60, pp. 359-372, 1995.
4. J. Roider, N. A. Michaud, T. J. Flotte, and R. Birngruber, "Response of the Retinal Pigment Epithelium to Selective Photocoagulation", Arch. Ophthalmol. 110, pp. 1786-1792, 1992.
5. J. Roider, F. Hillenkamp, T. J. Flotte, and R. Birngruber, "Microphotocoagulation: Selective effects of repetitive short laser pulses", Proc. Nat. Acad. Sci. USA 90, pp. 8463-8647, 1993.
6. J. Roider, C. Wirbelauer, R. Brinkmann, H. Laqua, and R. Birngruber, "Control and detection of subthreshold effects in the first clinical trial of macular diseases", Inv. Opthalmol. vis. sci. 39, pp. 104, 1998.
7. J. Roider, R. Brinkmann, C. Wirbelauer, H. Laqua, and R. Birngruber, "Subthreshold (retinal pigment epithelium) photocoagulation in macular diseases: a pilot study", Br J Ophthalmol 84, pp. 40-47, 2000.
8. J. Roider, C. Wirbelauer, R. Brinkmann, H. Laqua, and R. Birngruber, "Variability of RPE reaction in two cases after selective RPE laser effects in prophylactic treatment of drusen", Graefe's Arch Clin Exp Ophthalmol 237, pp. 45-50, 1999.
9. J. Roider, R. Brinkmann, C. Wirbelauer, H. Laqua, and R. Birngruber, "Retinal sparing by selective retinal pigment epithelial photocoagulation", Arch Ophthalmol 117, pp. 1028-1034, 1999.
10. ANSI, Standard Z136.1: American Standard for the Safe Use of Lasers. American Standards Institute, 1993.
11. W. T. Ham, H. A. Mueller, M. L. Wolbarsht, and D. H. Sliney, "Evaluation of retinal exposures from repetitively pulsed and scanning lasers", Health Physics 54, pp. 337-344, 1988.
12. B. E. Stuck, D. J. Lund, and E. S. Beatrice, Repetitive Pulse Laser Data and Permissible Exposure Limits, vol. Report No. 58. Lettermann Army Institute of Research, Presidio of San Francisco, San Fancisco, 1978.
13. R. Brinkmann, G. Hüttmann, J. Rögener, J. Roider, R. Birngruber, and C. P. Lin, "Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen", Lasers Surg Med 27, pp. 451-464, 2000.
14. C. Framme, G. Schuele, J. Roider, D. Kracht, R. Birngruber, and R. Brinkmann, "Threshold determinations for selective RPE defects with repetitive pulsed microsecond laser systems in rabbits", submitted to Ophth surg las, 2000.