메뉴 건너뛰기




Volumn 58, Issue 6, 2002, Pages 395-402

Pharmacokinetics of mono-3′- and mono-4′-0-(β-hydroxyethyl)-rutoside derivatives, after single doses of Venoruton powder in healthy volunteers

Author keywords

Hydroxyethylrutosides; Pharmacokinetics

Indexed keywords

3' O (BETA HYDROXYETHYL)QUERCETIN; 4' O (BETA HYDROXYETHYL)QUERCETIN; MONOXERUTIN; RUTOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0036378983     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-002-0472-3     Document Type: Article
Times cited : (12)

References (22)
  • 1
    • 0028024957 scopus 로고
    • Meta-analysis of hydroxyethylrutosides in the treatment of chronic venous insufficiency
    • Poynard T, Valterio C (1994) Meta-analysis of hydroxyethylrutosides in the treatment of chronic venous insufficiency. Vasa 23:244-250
    • (1994) Vasa , vol.23 , pp. 244-250
    • Poynard, T.1    Valterio, C.2
  • 3
    • 0029783828 scopus 로고    scopus 로고
    • A double-blind clinical trial of hydroxyethylrutosides in the treatment of the symptoms and signs of chronic venous insufficiency
    • Cloarec M, Clément R, Griton P (1996) A double-blind clinical trial of hydroxyethylrutosides in the treatment of the symptoms and signs of chronic venous insufficiency. Phlebology 11:76-82
    • (1996) Phlebology , vol.11 , pp. 76-82
    • Cloarec, M.1    Clément, R.2    Griton, P.3
  • 4
    • 0024400202 scopus 로고
    • 2 measurements, leg volumetry and ambulatory venous pressure measurements
    • 2 measurements, leg volumetry and ambulatory venous pressure measurements. Vasa 18:146-151
    • (1989) Vasa , vol.18 , pp. 146-151
    • Belcaro, G.1    Rulo, A.2    Candiani, C.3
  • 5
    • 0028335119 scopus 로고
    • A clinical comparison of two doses of O-(β-hydroxyethyl)-ruto-sides (oxerutins) in patients with chronic venous insufficiency
    • Diebschlag W, Nocker W, Lehmacher W, Rehn D (1994) A clinical comparison of two doses of O-(β-hydroxyethyl)-ruto-sides (oxerutins) in patients with chronic venous insufficiency. J Pharm Med 4:7-14
    • (1994) J Pharm Med , vol.4 , pp. 7-14
    • Diebschlag, W.1    Nocker, W.2    Lehmacher, W.3    Rehn, D.4
  • 7
    • 0023548365 scopus 로고
    • Hydrolysis of dietary flavonoid glycosides by strains of intestinal bacteroides from humans
    • Bokkenheuser VD, Shackleton CHL, Winter J (1987) Hydrolysis of dietary flavonoid glycosides by strains of intestinal bacteroides from humans. Biochem J 248:953-956
    • (1987) Biochem J , vol.248 , pp. 953-956
    • Bokkenheuser, V.D.1    Shackleton, C.H.L.2    Winter, J.3
  • 8
    • 0032566518 scopus 로고    scopus 로고
    • Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity
    • Day AJ, DuPont MS, Ridley S, Rhodes M, Rhodes MJC, Morgan MRA, Williamson G (1998) Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity. FEBS Lett 436:71-75
    • (1998) FEBS Lett , vol.436 , pp. 71-75
    • Day, A.J.1    DuPont, M.S.2    Ridley, S.3    Rhodes, M.4    Rhodes, M.J.C.5    Morgan, M.R.A.6    Williamson, G.7
  • 10
    • 0016333752 scopus 로고
    • Metabolism of the hydroxyethylrutosides III - The fate of orally administered hydroxyethylrutosides in laboratory animals - Metabolism by rat intestinal microflora in vitro
    • Barrow A, Griffiths LA (1974) Metabolism of the hydroxy-ethylrutosides III - The fate of orally administered hydroxy-ethylrutosides in laboratory animals - Metabolism by rat intestinal microflora in vitro. Xenobiotica 4:743-754
    • (1974) Xenobiotica , vol.4 , pp. 743-754
    • Barrow, A.1    Griffiths, L.A.2
  • 11
    • 0021712193 scopus 로고
    • Metabolism and pharmacokinetics of hydroxyethylated rutosides in animals and man
    • Balant LP, Wermeille M, Griffiths LA (1984) Metabolism and pharmacokinetics of hydroxyethylated rutosides in animals and man. Drug Metabol Drug Interact 5:1-24
    • (1984) Drug Metabol Drug Interact , vol.5 , pp. 1-24
    • Balant, L.P.1    Wermeille, M.2    Griffiths, L.A.3
  • 13
    • 0000722192 scopus 로고
    • Noncompartmental analysis based on statistical moment theory
    • Marcel Dekker, New York
    • Gibaldi M, Perrier D (1982) Noncompartmental analysis based on statistical moment theory. In: Pharmacokinetics, 2nd edn. Marcel Dekker, New York, pp 409-417
    • (1982) Pharmacokinetics, 2nd Edn. , pp. 409-417
    • Gibaldi, M.1    Perrier, D.2
  • 14
    • 0016811010 scopus 로고
    • Disposition of quercetin in man after single oral and intravenous doses
    • Gugler R, Leschik M, Dengler HJ (1975) Disposition of quercetin in man after single oral and intravenous doses. Eur J Clin Pharmacol 9:229-234
    • (1975) Eur J Clin Pharmacol , vol.9 , pp. 229-234
    • Gugler, R.1    Leschik, M.2    Dengler, H.J.3
  • 15
    • 0030039554 scopus 로고    scopus 로고
    • Investigation of the efficacy of oxerutins compared to placebo in patients with chronic venous insufficiency treated with compression stockings
    • Unkauf M, Rehn D, Klinger J, Motte S de la, Großmann K (1996) Investigation of the efficacy of oxerutins compared to placebo in patients with chronic venous insufficiency treated with compression stockings. Arzneimittelforschung (Sonderdruck) 46:478-482
    • (1996) Arzneimittelforschung (Sonderdruck) , vol.46 , pp. 478-482
    • Unkauf, M.1    Rehn, D.2    Klinger, J.3    De la Motte, S.4    Großmann, K.5
  • 17
    • 0018143506 scopus 로고
    • Spectrophotofluorometric analysis of 3′,4′,7-tris[O-(beta-hydroxyethyl)]rutoside in urine
    • Tan HSI, Mowery PJ, Ritschel WA, Neu C (1978) Spectrophotofluorometric analysis of 3′,4′,7-tris[O-(beta-hydroxyethyl)]rutoside in urine. J Pharm Sci 67:1142-1144
    • (1978) J Pharm Sci , vol.67 , pp. 1142-1144
    • Tan, H.S.I.1    Mowery, P.J.2    Ritschel, W.A.3    Neu, C.4
  • 18
    • 0015983061 scopus 로고
    • Metabolism of the hydroxyethylrutosides II excretion and metabolism of 3, 4, 7-tri-O-(β-hydroxyethyl)rutoside and related compounds in laboratory animals after parenteral administration
    • Barrow A, Griffiths LA (1974) Metabolism of the hydroxyethylrutosides II excretion and metabolism of 3, 4, 7-tri-O-(β-hydroxyethyl)rutoside and related compounds in laboratory animals after parenteral administration. Xenobiotica 4:1-16
    • (1974) Xenobiotica , vol.4 , pp. 1-16
    • Barrow, A.1    Griffiths, L.A.2
  • 19
    • 0017597757 scopus 로고
    • Enterohepatic cycling of o-(β-hydroxyethyl)-rutosides and their biliary metabolites in the rat
    • Hackett AM, Griffiths LA (1977) Enterohepatic cycling of o-(β-hydroxyethyl)-rutosides and their biliary metabolites in the rat. Experiencia 33:161-163
    • (1977) Experiencia , vol.33 , pp. 161-163
    • Hackett, A.M.1    Griffiths, L.A.2
  • 20
    • 0029832833 scopus 로고    scopus 로고
    • Dietary quercetin glycosides: Antioxidant activity and induction of the anticarcinogenic phase II marker enzyme quinone reductase in Hepalclc7 cells
    • Williamson G, Plumb GW, Uda Y, Price KR, Rhodes MJC (1996) Dietaryquercetin glycosides: antioxidant activity and induction of the anticarcinogenic phase II marker enzyme quinone reductase in Hepalclc7 cells. Carcinogenesis 17:2385-2387
    • (1996) Carcinogenesis , vol.17 , pp. 2385-2387
    • Williamson, G.1    Plumb, G.W.2    Uda, Y.3    Price, K.R.4    Rhodes, M.J.C.5
  • 22
    • 0033661837 scopus 로고    scopus 로고
    • Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers
    • Erlund I, Kosonen T, Alfthan G, Mäenpää J et al. (2000) Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers. Eur J Clin Pharmacol 56:545-553
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 545-553
    • Erlund, I.1    Kosonen, T.2    Alfthan, G.3    Mäenpää, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.