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Volumn 80, Issue 6, 2002, Pages 699-707

Enzymatic hydrolysis of β-lactam antibiotics at low pH in a two-phase "aqueous solution - Water-immiscible organic solvent" system

(2) Chilov, Ghermes G a Švedas, Vytas K a

a MOSCOW STATE UNIVERSITY (Russian Federation)

Author keywords

lactam antibiotic nuclei; Enzymatic hydrolysis; Penicillin acylase; Supersaturation; Two phase systems

Indexed keywords

ANTIBIOTICS; ENZYMES; HYDROLYSIS; SOLVENTS; SYNTHESIS (CHEMICAL); THERMODYNAMICS;

ACIDIFICATION;

CHEMICAL ANALYSIS;

6 AMINOPENICILLANIC ACID; 7 AMINODESACETOXYCEPHALOSPORANIC ACID; BETA LACTAM ANTIBIOTIC; CARBOXYLIC ACID; CEPHALOSPORIN DERIVATIVE; HEXANOIC ACID; N PHENYLACETAMIDODESACETOXYCEPHALOSPORINIC ACID; ORGANIC SOLVENT; PENICILLIN G; UNCLASSIFIED DRUG; WATER;

ACIDIFICATION; ACIDITY; ALKALINITY; AQUEOUS SOLUTION; ARTICLE; BIOSYNTHESIS; CATALYSIS; DRUG SYNTHESIS; DRUG TRANSFORMATION; EXTRACTION; HYDROLYSIS; MODEL; PH; PRECIPITATION; THERMODYNAMICS;

EID: 0036375596 PISSN: 00084042 EISSN: None Source Type: Journal
DOI: 10.1139/v02-096 Document Type: Article

Times cited : (13)

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