Amphicrine carcinoma of breast with giant granules: An immunohistochemical, histochemical and ultrastructural study

Journal of Submicroscopic Cytology and Pathology

Volumn 34, Issue 1, 2002, Pages 27-36

  Eyden, B ^a   Banerjee, S S ^a   Nesland, J M ^b  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Amphicrine; Breast; Casein; Ductal carcinoma; Electron microscopy; Neuroendocrine

Indexed keywords

CASEIN; NEURON SPECIFIC ENOLASE; SOMATOSTATIN; SYNAPTOPHYSIN;

AGED; AMPHICRINE CARCINOMA; ARTICLE; BASEMENT MEMBRANE; BREAST CARCINOMA; CANCER GRADING; CASE REPORT; CELL DIFFERENTIATION; CELL GRANULE; CELL SHAPE; CELL ULTRASTRUCTURE; CYTOPLASM; DESMOSOME; ELECTRON MICROSCOPY; FEMALE; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NEUROENDOCRINE TUMOR; STAINING; TONOFILAMENT; TUMOR CELL; BREAST TUMOR; CARCINOMA; METABOLISM; PAGET NIPPLE DISEASE; ULTRASTRUCTURE;

POMACANTHUS MACULOSUS;

AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, NEUROENDOCRINE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY;

EID: 0036372312     PISSN: 11229497     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. AILLET G., FIKS M., GUILLARD Y., GAILLARD F., BARBIN J.G., AUGER J.J. and LE BODIC M.F., 1987. Etude immunohistochimique de 4 cas de carcinomes mucoides er argyrophiles du sein. Ann. Pathol., 7, 325-329.
2. AZZOPARDI J.G., MURETTO P., GODDEERIS P., EUSEBI V. and LAUWERYNS J.M., 1982. 'Carcinoid' tumours of the breast: the morphological spectrum of argyrophil carcinomas. Histopathology, 6, 549-569.
3. BENLOT C., LEVY L., FONTANAUD P., ROCHE A., ROUANNET P. and JOUBERT D., 1997. Somatostatin and growth hormone-releasing hormone in normal and tumoral breast tissue: endogenous content, in vitro pulsatile release, and regulation. J Clin. Endocrinol. Metab., 82, 690-696.
4. BERGER G., FRAPPART L., GUILLAUD M., MALLET-GUY Y., PATRICOT L.M. and FEROLDI J., 1982. Tumeurs amphicrines, mucoides et argyrophiles, du sein. Etude histochimique er ultrastructurale de deux observations. Ann. Pathol., 2, 213-222.
5. BINGHAM E.W. and FARRELL JR. H.M., 1977. Phosphorylation of casein by the lactating mammary gland: a review. J. Dairy Sci., 60, 1199-1207.
6. CAPELLA C., EUSEBI V., MANN B. and AZZOPARDI J.G., 1980. Endocrine differentiation in mucoid carcinoma of the breast. Histopathology, 4, 613-630.
7. CAPELLA C., USELLINI L., PAPOTTI M., MACRI L., FINZI G., EUSEBI V. and BUSSOLATI G., 1990. Ultrastructural features of neuroendocrine differentiated carcinomas of the breast. Ultrastruct. Pathol., 14, 321-334.
8. CHEJFEC G., CAPELLA C., SOLCIA E., JOA W. and GOULD V.E., 1985. Amphicrine cells, dysplasias, and neoplasias. Cancer, 56, 2683-2690.
9. CIOCCA D.R., PUY L.A., FASOLI L.C., TELLO O., AZNAR J.C., GAGO F.E., PAPA S.I. and SONEGO R., 1990. Corticotropin-releasing hormone, lutcinizing hormone-related hormone, growth hormone-releasing hormone, and somatostatin-like immunoreactivities in biopsies from breast cancer patients. Breast Cancer Res. Treat., 15, 175-184.
10. CLAYTON F., SIBLEY R.K., ORDONEZ N.G. and HANSSEN G., 1982. Argyrophilic breast carcinomas. Evidence of lactational differentiation. Am. J. Surg. Pathol., 6, 323-333.
11. DICKERSIN G.R., MALUF H.M. and KOERNER F.C., 1997. Solid papillary carcinoma of breast: an ultrastructural study. Ultrastruct. Pathol., 21, 153-161.
12. EYDEN B., 1996. 'Organelles in Tumor Diagnosis: an Ultrastructural Atlas'. Igaku-Shoin, New York and Tokyo, pp. 50-51.
13. EYDEN B.P., CROSS P.A. and HARRIS M., 1990. The ultrastructure of signet-ring cell non-Hodgkin's lymphoma. Virchows Arch. A. Pathol. Anat., 417, 395-404.
14. FETISSOF F., DUBOIS M.P., ARBEILLE-BRASSART B., LANSAC J. and JOBARD P., 1983. Argyrophilic cells in mammary carcinoma. Hum. Pathol., 14, 127-134.
15. GHADIALLY F.N., 1988a. 'Ultrastructural Pathology of the Cell and Matrix'. Butterworths, London, 3rd ed., vol. 1, pp. 392-395.
16. GHADIALLY F.N., 1988b. 'Ultrastructural Pathology of the Cell and Matrix'. Butterworths, London, 3rd ed., vol. 1, pp. 390-391.
17. HULL M.T. and WARFEL K.A., 1987. Mucinous breast carcinomas with abundant intracytoplasmic mucin and neuroendocrine features: light microscopic, immunohistochemical, and ultrastructural study. Ultrastruct Pathol., 11, 29-38.
18. KANBAYASHI C., OKA K., HAKOZAKI H., SAITO H., SANDO N., TOBITA T., KOYAMATSU S., MORIYA T. and MORI N., 2001. Solid papillary carcinoma of the breast: report of two cases. Ultrastruct. Pathol., 25, 147-152.
19. MALUF H.M., ZUKERBERG L.R., DICKERSIN G.R. and KOERNER F.C., 1991. Spindle-cell argyrophilic mucin-producing carcinoma of the breast. Histological, ultrastructural, and immunohistochemical studies of two cases. Am. J. Surg. Pathol., 15, 677-686.
20. MÁNDOKY L., 1999. Amphicrine tumor. Path. Oncol. Res., 5, 239-244.
21. NAKAGAWA H., SHIKATA N., SENZAKI H., UEMURA Y., INOUE T., KASHU S. and TSUBURA A., 2000. Mucinous carcinoma of the breast with neuroendocrine differentiation. Pathol. Int., 50, 644-648.
22. NESLAND J.M., HOLM R., OTTESTAD L., KARLSEN K.O. and JOHANNESSEN J.V., 1988. Neuroendocrine activity in metastatic breast carcinomas. Acta Pathol. Microbiol. Immunol. Stand. A, 2, 204-214.
23. NESLAND J.M., OTTESTAD L., HEIKILLA R., HOLM R., TVEIT K. and BORRESEN A.L., 1991. C-erbB-2 protein and neuroendocrine expression in breast carcinomas. Anticancer Res , 11, 161-167.
24. PAPOTTI M., MACRI L., FINZI G., CAPELLA C., EUSEBI V. and BUSSOLATI G., 1989. Neuroendocrine differentiation in carcinomas of the breast: a study of 51 cases. Sem. Diag. Pathol., 6, 174-188.
25. PAYNE C.M., 1993. Use of the uranaffin reaction in the identification of neuroendocrine granules. Ultrastruct. Pathol., 17, 49-52.
26. RASMUSSEN B.B. and HENSCHEL A., 1985. Ultrastrucrural characteristics and variations in human mucinous breast carcinomas. Pathol. Res. Pract., 180, 28-35.
27. SANTINI D., BAZZOCCHI F., PILERI S., GOVONI E., TAFFURELLI M., GRASSIGLI A., DOMENICO M. and MARTINELLI G., 1985. Mammary carcinoma with argyrophilic cells: an immunohistochemical and ultrastructural study. Tumori, 71, 331-338.
28. SPRING-MILLS E.J., STEARNS S.B., NUMANN P.J. and SMITH P.H., 1984. Immunocytochemical localization of insulin- and somatostatin-like material in human breast tumors. Life Sci., 35, 185-190.
29. VASSALLO G., CAPELLA C. and SOLCIA E., 1971. Grimelius' silver stain for endocrine cell granules, as shown by electron microscopy. Stain. Technol., 46, 7-13.