Changes in lung deposition of aerosols due to hygroscopic growth: A fast SPECT study

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung

Volumn 15, Issue 3, 2002, Pages 307-311

  Chan, Hak Kim ^a   Eberl, Stefan ^b   Daviskas, Evangelia ^b   Constable, Christopher ^b   Young, Iven ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b RPAH   (Australia)

Author keywords

Dynamic SPECT; Hygroscopic growth; Penetration index; Radioaerosol clearance; Radioaerosol deposition and distribution

Indexed keywords

PENTETATE TECHNETIUM TC 99M; SODIUM CHLORIDE;

AEROSOL; CONFERENCE PAPER; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; NORMAL HUMAN; PARTICLE SIZE; QUANTITATIVE ANALYSIS; SCINTILLATION CAMERA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; WETTABILITY;

EID: 0036365650     PISSN: 08942684     EISSN: None     Source Type: Journal    
DOI: 10.1089/089426802760292654     Document Type: Conference Paper

References (13)

1. Growth rate measurements and deposition modelling of hygroscopic aerosols in human tracheobronchial models
2. Aerosol particle growth in the human airways using a calculated humidity profile
3. Maximization of pulmonary hygroscopic aerosol deposition
4. Study of the hygroscopic properties of selected pharmaceutical aerosols using single particle levitation
5. Regional deposition of saline aerosols of different tonicities in normal and asthmatic subjects
6. Regional deposition of nebulised hypodense nonisotonic solutions in the human respiratory tract
7. Use of single photon emission computed tomography in aerosol studies
8. Aerosol deposition and clearance measurement: A novel technique using dynamic SPET
9. The use of laser diffraction for the evaluation of the aerosol clouds generated by medical nebulizers
10. Apparatus for the control of breathing pattern during aerosol inhalation
11. Evaluation of the accuracy and precision of lung aerosol deposition measurement from single-photon emission computed tomography using simulation
12. Regional deposition of inhaled hygroscopic aerosols: In vivo SPECT compared with mathematical modeling
13. Coupled mass and energy transport phenomena in aerosol/vapor-laden gases. I. Theory of the hygroscopic aerosol effects on temperature and relative humidity patterns of inspired air