Meclofenamic acid for inhibition of human vascular smooth muscle cell proliferation and migration: An in vitro study

CardioVascular and Interventional Radiology

Volumn 25, Issue 1, 2002, Pages 57-63

  Schober, Wolfgang ^a   Kehlbach, Rainer ^a   Gebert, Regina ^a   Wiskirchen, Jakub ^a   Rodegerdts, Enno ^a   Claussen, Claus D ^a   Duda, Stephan H ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

FACS; MAP kinase; Migration; Pharmacology; Vascular smooth muscle cell proliferation

Indexed keywords

MECLOFENAMIC ACID; PROSTAGLANDIN SYNTHASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN P42; PROTEIN P44;

ARTICLE; CELL CULTURE; CELL CYCLE; CELL DIVISION; CELL MOTION; CYTOLOGY; DRUG EFFECT; HUMAN; IN VITRO STUDY; VASCULAR SMOOTH MUSCLE; ANGIOPLASTY; AORTA; CELL CYCLE G2 PHASE; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CLONOGENESIS; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; FLOW CYTOMETRY; HUMAN TISSUE; PRIORITY JOURNAL; RESTENOSIS; WESTERN BLOTTING;

CELL CYCLE; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; CYCLOOXYGENASE INHIBITORS; HUMANS; MECLOFENAMIC ACID; MUSCLE, SMOOTH, VASCULAR;

EID: 0036359842     PISSN: 01741551     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00270-001-0077-8     Document Type: Article

References (47)

1. Popma JJ, Topol EJ (1990) Factors influencing restenosis after coronary angioplasty. Am J Med 88:16N-24N
2. Kuntz RE, Safian RD, Levine MJ, Reis GJ, Diver DJ, Baim DS (1992) Novel approach to the analysis of restenosis after the use of three new coronary devices. J Am Coll Cardiol 19:1493-1499
3. Jeans WD, Armstrong S, Cole SEA, Horrocks M, Baird RN (1990) Fate of patients undergoing transluminal angioplasty for lower-limb ischemia. Radiology 177:559-564
4. Johnston KW (1992) Femoral and popliteal arteries: Reanalysis of results of balloon angioplasty. Radiology 183:767-771
5. Dangas G, Fuster V (1996) Management of restenosis after coronary intervention. Am Heart J 132:428-436
6. Hanke H, Hassenstein S, Ulmer A, Kamenz J, Oberhoff M, Haase KK, Baumbach A, Gown AM, Karsch KR (1994) Accumulation of macrophages in the arterial vessel wall following experimental balloon angioplasty. Eur Heart J 15:691-698
7. Hanke H, Strohschneider T, Oberhoff M, Betz E, Karsch KR (1990) Time course of smooth muscle cell proliferation in the intima and media of arteries following experimental angioplasty. Circ Res 67:651-659
8. Clowes AW, Reidy MA, Clowes MM (1987) Kinetics of cellular proliferation after arterial injury. Lab Invest 49:327-333
9. Ferns GAA, Raines EW, Sprugel K, Motari A, Reidy M, Ross R (1991) Inhibition of neointimal smooth muscle cell accumulation after angioplasty by an antibody to PDGF. Science 253:1129-1132
10. Casscells W (1992) Migration of smooth muscle and endothelial cells: Critical events in restenosis. Circulation 86:723-729
11. Fukuyama J, Ichikawa K, Miyazawa K, Hamano S, Shibata N, Ujiie A (1996) Tranilast suppresses intimal hyperplasia in the balloon injury model and cuff treatment model in rabbits. Jpn J Pharmacol 70:321-327
12. Miyazawa N, Umemura K, Kondo K, Nakashima M (1997) Effects of Pemirolast and Tranilast on intimal thickening after arterial injury in the rat. J Cardiovasc Pharmacol 30:157-162
13. Kosuga K, Tamai H, Ueda K, Hsu Y-S, Ono S, Tanaka S, Doi T, Myou-U W, Motohara S, Uehata H (1997) Effectiveness of tranilast on restenosis after directional coronary atherectomy. Am Heart J 134:712-718
14. Ueda K, Tamai H, Hsu Y-S (1995) Efficacy of tranilast on restenosis after coronary angioplasty: Is there any rebound phenomenon after ceasing tranilast at 3 months? J Am Coll Cardiol 25:225A
15. Matsell DG, Gaber LW, Malik KU (1994) Cytokine stimulation of prostaglandin production inhibits the proliferation of serum-stimulated mesangial cells. Kidney Int 45:159-165
16. Hu Y, Cheng L, Hochleitner BW (1997) Activation of mitogen-activated protein kinases (ERK/JNK) and AP-1 transcription factor in rat carotid arteries after balloon injury. Arterioscler Thromb Vasc Biol 17:2808-2816
17. Epstein SE, Speir E, Unger EF, Guzman RJ, Finkel T (1994) The basis of molecular strategies for treating coronary restenosis after angioplasty. J Am Coll Cardiol 23:1278-1288
18. Fingerle J, Johnson R, Clowes AW, Majewsky MW, Reidy MA (1989) Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery. Proc Natl Acad Sci USA 86:8412-8416
19. Jawien A, Bowen-Pope DF, Lindner V, Schwartz SM, Clowes AW (1992) Platelet derived growth factor promotes smooth muscle cell migration and intimal thickening in a rat model of balloon angioplasty. J Clin Invest 89:507-511
20. Ross R (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362:801-809
21. White CW, Knudson M, Schmidt D (1987) Neither ticlopidine nor aspirin-dipyridamol prevents restenosis post-PTCA: Results from a randomized placebo-controlled multicenter trial. Circulation 76:IV-213
22. Muffson L, Balck A, Roubin G (1988) A randomized trial of aspirin in PTCA: Effect of high vs low dose aspirin on major complications and restenosis. J Am Coll Cardiol 11:236A
23. Betrand ME, Allain H, LaBlanche JM (1990) Results of a randomized trial of ticlopidine versus placebo for the prevention of acute closure and restenosis after coronary angioplasty (PTCA): The TACT Study. Circulation 82:III-190
24. Cairns JA, Gill JB, Morton B (1994) Enoxaparine and Maxepa for the prevention of angioplasty restenosis (EMPAR). Circulation 90:I-651
25. Cavero PG, O'Keefe JHJ, Stone GW (1995) Lovastatin and probucol for the prevention of restenosis after coronary angioplasty. J Am Coll Cardiol 25:226A
26. Leaf A, Jorgensen MB, Jacobs AK (1994) Do fish oils prevent restenosis after coronary angioplasty? Circulation 90:2248-2257
27. Pepine CJ, Hirhfeld JW, Mac Donald RG (1990) A controlled trial of corticosteroids to prevent restenosis after coronary angioplasty. Circulation 81:1735-1761
28. Topol EJ, Califf RM, Weisman HF (1994) Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months. Lancet 343:881-886
29. EPILOG, Investigators (1997) Effect of the platelet glycoprotein IIb/IIIa receptor inhibitor abciximab with lower heparin dosages on ischemic complications of percutaneous coronary revascularization. N Engl J Med 336:1689-1696
30. Maresta A, Balducelli M, Cantini L (1994) Trapidil (triazolopyrimidine), a platelet-derived growth factor antagonist, reduces restenosis after percutaneous transluminal coronary angioplasty. Circulation 90: 2710-2715
31. Eriksen U, Amtorp O, Bagger JP (1995) Randomized double-blind Scandinavian trial of angiopeptin versus placebo for the prevention of clinical events and restenosis after coronary balloon angioplasty. Am Heart J 130:1-8
32. Tamai H for the TREAT Investigators (1994) The impact of tranilast on restenosis following coronary angioplasty: the Tranilast Restenosis Following Angioplasty Trial (TREAT). Circulation 90:I-652
33. Tanaka K, Honda M, Kuramochi T, Morioka S (1994) Prominent inhibitory effects of tranilast on migration and proliferation of and collagen synthesis by vascular smooth muscle cells. Atherosclerosis 107:179-185
34. Kosuga K, Tamai H, Ueda K, Hsu Y-S, Ono S, Tanaka S, Doi T, Myou-U W, Motohara S, Uehata H (1997) Effectiveness of tranilast on restenosis after directional coronary atherectomy. Am Heart J 134:712-718
35. Hutchison TA, Shahan DR, Anderson ML (1999) Drugdex system. Micromedex, Englewood, Colorado (edition expires 1999)
36. Davis RJ (1993) The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553-14556
37. Seger R, Krebs EG (1995) The MAPK signaling kaskade. FASEB J 9:726-735
38. Sturgill TW, Ray LB, Erikson E, Maller JL (1988) Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 334:715-718
39. Lin L-L, Wartmann M, Lin AY, Knopf JL, Seth A, Davis RJ (1993) cPLA2 is phosphorylated and activated by MAP kinase. Cell 72:269-278
40. Chen R-H, Abate C, Blenis J (1993) Phosphorylation of the c-fos transcription domain by MAP kinase and 90-kDa S6 kinase. Proc Natl Acad Sci USA 90:10952-10956
41. Prod Info Meclofenamte sodium (1998) Micromedex Healthcare series. Micromedex, Englewood, Colorado
42. Preston SN (1978) Safety of sodium meclofenamate. Curr Ther Res 23 S107-S112
43. Riessen R, Isner J (1994) Prospects for site-specific delivery of pharmacological and molecular therapies. J Am Coll Cardiol 23:1234-1244
44. Lambert TL, Vishva D, Rechavia E, Forrester JS, Litvack F, Eigler NL (1994) Localized arterial wall drug delivery from a polymer-coated removable metallic stent: Kinetics, distribution, and bioactivity of forskolin. Circulation 90:1003-1011
45. Herdeg C (1998) Antiproliferative stent coating: Taxol and related compounds. Semin Intervent Cardiol 3:197-99
46. Sinclair WK (1968) Cyclic x-ray responses in mammalian cells in vitro. Radiat Res 33:620-643
47. Fortunato JE, Mauceri HJ, Kocharyan H, Song RH, Salloum R, Vosicky J, Swedberg K, Malik S, Abusharif F, Glagov S, Weichselbaum RR, Bassiouni HS (2000) Gene therapy enhances the antiproliferative effect of radiation in intimal hyperplasia. J Surg Res 89:155-162