New Triterpenoidal Alkaloids from Buxus sempervirens

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 57, Issue 1-2, 2002, Pages 21-28

  Ata, Athar ^a   Naz, Samina ^b   Choudhary, M Iqbal ^b   Atta ur Rahman, ^b   Sener, Bilge ^c   Turkoz, Songul ^c  

^a UNIVERSITY OF WINNIPEG   (Canada)

^b UNIVERSITY OF KARACHI   (Pakistan)

^c GAZI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

BUXUS SEMPERVIRENS; LEMNA MINOR;

ALKALOID; ANTIINFECTIVE AGENT; TRITERPENE;

ANGIOSPERM; ARTICLE; BACTERIUM; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; TURKEY (REPUBLIC);

ALKALOIDS; ANGIOSPERMS; ANTI-BACTERIAL AGENTS; BACTERIA; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PLANT ROOTS; TRITERPENES; TURKEY;

EID: 0036359687     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2002-1-204     Document Type: Article

References (17)

1. Ata A. (1995), Phytochemical and structural studies on the chemical constituents of Buxus hildebrandtii and B. sempervirens. Ph. D. Dissertation, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
2. Atta-ur-Rahman (1989), One-and Two-Dimensional NMR Spectroscopy. Elsevier Science Publ., Amsterdam.
3. Atta-ur-Rahman, Ata A., Naz S., Choudhary M. I., Sener B. and Turkoz S. (1999), New steroidal alkaloids from the roots of Buxus sempervirens. J. Nat. Prod., 62, 665-669.
4. Atta-ur-Rahman and Choudhary M. I. (1988), Studies in Natural Products Chemistry (Att-ur-Rahman, ed.). Elsevier Science Publ., Amsterdam, Vol. 2, pp. 175-189; Structural studies on new steroidal alkaloids of Buxus papillosa.
5. Atta-ur-Rahman and Choudhary, M. I. (1996), Solving Problems with NMR Spectrocopy. Academic Press, New York.
6. Atta-ur-Rahman, Nisa M. and Jahan K. (1985), Isolation and structure of buxaminol-G, an alkaloid from Buxus papillosa. Phytochemistry 24, 1398-1399.
7. Brown Jr. K. S. and Kupchan S. M. (1962), The configuration of cyclobuxine and its interaction with cycloeu-calenol, J. Am. Chem. Soc., 84, 4592-4594.
8. Budzikiewicz H. (1972) In: Steroids. Biochemical Application of Mass Spectrometery (R. G. Waller, ed.). Wiley-Interscience, New York, pp. 251-271.
9. Cordell G. A. (1981), Buxus alkaloids. In: Introduction to Alkaloids; A Biogenetic Approach. Wiley Interscience, New York, pp. 907-925.
10. Durant J., Chantre P., Gonzalez G., Vandermander J., Halfon P., Rousse B., Guedon D., Rahelinirina V., Chamaret S., Montagnier L. and Dellamonica P. (1998), Efficacy and safety of Buxus sempervirens L. preparations (SPV30) in HIV asymptomatic patients: a multicentre, randomized, double-blind, placebocontrolled trail. Phytomedicine 5, 1-10.
11. Kupchan S. M., Kennedy R. M., Schleigh W. R. and Ohata G. (1967), Tetrahedron 23, 45-63.
12. Loru F., Duval D., Aumelas A., Akeb F., Guedon D. and Guedj R. (2000), Four steroidal alkaloids from the leaves of Buxus sempervirens. Phytochemistry 54, 951-957.
13. McMaughlin J. L., Ching-Jer C. and Smith D. (1991), In: Bench top bioassays for the discovery of bioactive natural products: An update. Frontiers in Natural Products Chemistry (Ed. Atta-ur-Rahman), Shamim Printing Press, Karachi, pp. 548-569.
14. Nakano T., Terao S. and Saeki Y. (1966), Buxus alkaloids VII. The isolation and the constitution of ten new alkaloids from weak-base fraction of two species, B. microphylla var. suffruticosa and B. microphylla var. suffruticosa major. J. Chem. Soc (C), 1412-1421.
15. Nakano T., Terao S., Saeki Y. and Jin K. D. (1966), Buxus Alkaloids VIII. The isolation and constitution of a new alkaloids from B. koreans and conversion of cyclomikuranine into cyclovirobuxine-A, J. Chem. Soc. (C), 1805-1810.
16. Wang Y. X., Liu J. W., Tan Y. H. and Sheng B. H. (1989), Positive inotropic effect of cycloprotobuxine-A on isolated guinea pig myocardium. Acta Pharmacol. Sinica 10, 516-519.
17. Wang Y. X., Tan Y. H. and Sheng B. H. (1992), Protective effect of cycloprotobuxine-A against cardiac arrhythmias induced by ouabain. Acta Pharmacol. Sinica 13, 226.