Novel 5-substituted-1H-tetrazole derivatives as potent glucose and lipid lowering agents

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 1, 2002, Pages 100-111

  Momose, Yu ^a   Maekawa, Tsuyoshi ^a   Odaka, Hiroyuki ^a   Ikeda, Hitoshi ^a   Souda, Takashi ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

5 (4 alkoxyphenylalkyl) 1H tetrazole; Antidiabetic agent; Glucose lowering effect; KKAy mouse; Lipid lowering effect; Wistar fatty rat

Indexed keywords

5 (4 ALKOXYPHENYL) 1H TETRAZOLE DERIVATIVE; 5 [3 [6 (5 METHYL 2 PHENYL 4 OXAZOLYLMETHOXY) 3 PYRIDYL]PROPYL] 1H TETRAZOLE; ANTILIPEMIC AGENT; AZIDE; CYCLOBUTANE; GLUCOSE; NITRILE; OXAZOLE; PIOGLITAZONE; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 1H TETRAZOLE; 1H-TETRAZOLE; 5 (3 (6 (5 METHYL 2 PHENYL 4 OXAZOLYL METHOXY) 3 PYRIDYL)PROPYL) 1H TETRAZOLE; 5-(3-(6-(5-METHYL-2-PHENYL-4-OXAZOLYL-METHOXY)-3-PYRIDYL)PROPYL)-1H-TETRAZOLE; ANTIDIABETIC AGENT; CELL RECEPTOR; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL;

ARTICLE; CYCLIZATION; DIABETES MELLITUS; DRUG ANTAGONISM; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; OBESITY; ANIMAL; BLOOD; CHEMISTRY; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; MOUSE; MOUSE STRAIN; RAT; SYNTHESIS; WISTAR RAT;

ANIMALS; ANTILIPEMIC AGENTS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; MICE; MICE, INBRED STRAINS; OBESITY; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TETRAZOLES; TRANSCRIPTION FACTORS; TRIGLYCERIDES;

EID: 0036357952     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.100     Document Type: Article

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