EEG abnormalities during treatment with typical and atypical antipsychotics

American Journal of Psychiatry

Volumn 159, Issue 1, 2002, Pages 109-115

  Centorrino, Franca ^a   Price, Bruce H ^a   Tuttle, Margaret ^a   Bahk, Won Myong ^a   Hennen, John ^a   Albert, Matthew J ^a   Baldessarini, Ross J ^a  

^a MCLEAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; BENZODIAZEPINE; CLOZAPINE; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE;

ARTICLE; BIPOLAR DISORDER; COMORBIDITY; DISEASE SEVERITY; DRUG EXPOSURE; DRUG POTENCY; EEG ABNORMALITY; HOSPITALIZATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MENTAL PATIENT; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; PSYCHOSIS; RISK ASSESSMENT; RISK FACTOR; SENESCENCE; ADOLESCENT; ADULT; AGED; COMPARATIVE STUDY; DRUG COMBINATION; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; FEMALE; MALE; MIDDLE AGED; PSYCHOLOGICAL ASPECT; PSYCHOLOGY; RISK; SCHIZOPHRENIA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIPSYCHOTIC AGENTS; DRUG THERAPY, COMBINATION; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; PSYCHOTIC DISORDERS; RISK; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 0036357464     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.159.1.109     Document Type: Article

References (37)

1. Berger H: Über das Elektrenkephalogram des Menschen. Arch Psychiatr Nervenkr 1929; 87:527-570
2. Fink M: EEG and behavior: association or disassociation in man? Integrative Psychiatry 1993; 9:108-123
3. Niedermeyer E, DaSilva F (eds): Electroencephalography: Basic Principles, Clinical Applications, and Related Fields. Baltimore, Williams & Wilkins, 1999
4. Stevens JR, Bigelow L, Denney D, Lipkin J, Livermore AH Jr, Rauscher F, Wyatt RJ: Telemetered EEG-EOG during psychotic behaviors of schizophrenia. Arch Gen Psychiatry 1979; 36:251-262
5. Bridgers SL: Epileptiform abnormalities discovered on electroencephalographic screening of psychiatric inpatients. Arch Neurol 1987; 44:312-316
6. Small JG, Milstein V, Malloy RV, Medlock CE, Klapper MH: Clinical and quantitative EEG studies of mania. J Affect Disord 1999; 53:217-224
7. Baldessarini RJ: Drugs and the treatment of psychiatric disorders: depression and anxiety disorders, in Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th ed. Edited by Hardman JG, Limbird LE, Gilman AG. New York, McGraw-Hill, 2001, pp 447-483
8. Baldessarini RJ, Tarazi FI: Drugs and the treatment of psychiatric disorders: psychosis and mania agents. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th ed. Ibid, pp 485-520
9. Roubicek J, Major I: EEG profile and behavioral changes after a single dose of clozapine in normals and schizophrenics. Biol Psychiatry 1977; 12:613-633
10. Moore NC, Tucker KA, Brin FB, Merai P, Shillcut SD, Coburn KL: Positive symptoms of schizophrenia: response to haloperidol and remoxipride is associated with increased alpha EEG activity. Hum Psychopharmacol 1997; 12:75-80
11. Itil TM, Soldatos C: Epileptogenic side effects of psychotic drugs: practical recommendation. JAMA 1990; 147:1069-1071
12. Silvestri RC, Bromfield EB, Khoshbin S: Clozapine-induced seizures and EEG abnormalities in ambulatory psychiatric patients. Ann Pharmacother 1998; 32:1147-1151
13. Devinsky O, Honigfeld G, Patin J: Clozapine-related seizures. Neurology 1991; 41:369-371
14. Baldessarini RJ, Katz B, Cotton P: Dissimilar dosing with high-potency and low-potency neuroleptics. Am J Psychiatry 1984; 141:748-752
15. American Electroencephalographic Society: Guidelines in EEG and evoked potentials. J Clin Neurophysiol 1986; 3(suppl 1):1-152
16. Santamaria J, Chiappa KH: The EEG in Drowsiness. New York, Demos Press, 1987
17. Daly DD, Pedley TA (eds): Current Practice of Clinical Electroencephalography. New York, Raven Press, 1990
18. Liukkonen J, Koponen HJ, Nousiainen U: Clinical picture and long-term course of epileptic seizures that occur during clozapine treatment. Psychiatry Res 1992; 44:107-112
19. Günther W, Baghai T, Naber D, Spatz R, Hippius H: EEG alterations and seizures during treatment with clozapine: retrospective study of 283 patients. Pharmacopsychiatry 1993; 26:69-74
20. Haring C, Neudorfer C, Schwitzer J, Hummer M, Saria A, Hinterhuber H, Fleischhacker WW: EEG alterations in patients treated with clozapine in relation to plasma levels. Psychopharmacology 1994; 114:97-100
21. Malow BA, Reese KB, Sato S, Bogard PJ, Malhotra AK, Su TP, Pickar D: Spectrum of EEG abnormalities during clozapine treatment. Electroencephalogr Clin Neurophysiol 1994; 91:205-211
22. Welch J, Manschreck T, Redmond D: Clozapine-induced seizures and EEG changes. J Neuropsychiatry Clin Neurosci 1994; 6:250-256
23. Risby ED, Epstein CM, Jewart RD, Nguyen BV, Morgan WN, Risch SC, Thrivikraman KV, Lewine RL: Clozapine-induced EEG abnormalities and clinical response to clozapine. J Neuropsychiatry Clin Neurosci 1995; 7:466-470
24. Freudenreich O, Weiner RD, McEvoy JP: Clozapine-induced electroencephalogram changes as a function of clozapine serum levels. Biol Psychiatry 1997; 42:132-137
25. Baldessarini RJ, Frankenburg FR: Clozapine: a novel antipsychotic agent. N Engl J Med 1991; 324:746-754
26. Centorrino F, Baldessarini RJ, Kando J, Frankenburg FR, Volpicelli SA, Puopolo PR, Flood JG: Serum concentrations of clozapine and its major metabolites: effects of cotreatment with fluoxetine or valproate. Am J Psychiatry 1994; 151:123-125
27. Umbricht D, Kane JM: Medical complications of new antipsychotic drugs. Schizophr Bull 1996; 22:475-483
28. Czobor P, Volavka J: Quantitative electroencephalogram examination of effects of risperidone in schizophrenic patients. J Clin Psychopharmacol 1993; 13:332-342
29. Beasley CM Jr, Tollefson GD, Tran PV: Safety of olanzapine. J Clin Psychiatry 1997; 58(suppl 10):13-17
30. Wyderski RJ, Starrett WG, Abou-Saif A: Fatal status epilepticus associated with olanzapine therapy. Ann Pharmacother 1999; 33:787-789
31. Wetzel H, Szegedi A, Hain C, Wiesner J, Schlegel S, Benkert O: Seroquel (ICI-204-636), a putative "atypical" antipsychotic, in schizophrenia with positive symptomatology: results of an open clinical trial and changes of neuroendocrinological and EEG parameters. Psychopharmacology (Berl) 1995; 119:231-238
32. Bente D, Itil T: Zur wirking des phenothiazinkorpes Megaphen auf das menschliche hirnstrombild. Arzneim Forsch 1954; 4:418-423
33. Helmchen H, Kanowski S: EEG changes under lithium (Li) treatment. Electroencephalogr Clin Neurophysiol 1971; 30:269
34. Koukkou M, Angst J, Zimmer D: Paroxysmal EEG activity and psychopathology during treatment with clozapine. Pharmakopsychiatr Neuropsychopharmakol 1979; 12:173-183
35. Stevens JR: Clozapine: the yin and yang of seizure psychosis. Biol Psychiatry 1995; 37:425-426
36. Wilson WH: Do anticonvulsants hinder clozapine treatment? Biol Psychiatry 1995; 37:132-133
37. Pillay SS, Stoll AL, Weiss MK, Tohen M, Zarate CA Jr, Banov MD, Cole JO: EEG abnormalities before clozapine therapy predict a good clinical response to clozapine. Ann Clin Psychiatry 1996; 8:1-5