Ricardo Miledi and the calcium hypothesis of neurotransmitter release

Nature Reviews Neuroscience

Volumn 3, Issue 1, 2002, Pages 71-76

  Jeng, Jade Ming ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEPHALOPODA;

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CALCIUM;

ANIMAL; ART; ARTICLE; CEPHALOPOD; HISTORY; METABOLISM; MEXICO; NERVE FIBER; NEUROMUSCULAR SYNAPSE; NEUROPHYSIOLOGY; PHYSIOLOGY; SYNAPTIC TRANSMISSION; UNITED STATES;

ANIMALS; AXONS; CALCIUM; DECAPODIFORMES; HISTORY, 20TH CENTURY; MEXICO; NEUROMUSCULAR JUNCTION; NEUROPHYSIOLOGY; NEUROTRANSMITTER AGENTS; PORTRAITS; SYNAPTIC TRANSMISSION; UNITED STATES;

EID: 0036356737     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn706     Document Type: Article

References (24)

1. Darnell, J., Lodish, H. & Baltimore, D. Molecular Cell Biology 2nd edn (Scientific American Books, New York, 1990).
2. Hall, Z. W. An introduction to Molecular Neurobiology (Sinauer Associates, Sunderland, Massachusetts, 1992).
3. Miledi, R. Transmitter release induced by injection of calcium ions into nerve terminals. Proc. R. Soc. Lond. B 183, 421-425 (1973).
4. Katz, B. & Miledi, R. A study of synaptic transmission in the absence of nerve impulses. J. Physiol. (Lond.) 192, 407-436 (1967).
5. Ringer, S. Concerning the influence exerted by each of the constituents of the blood on the contraction of the ventricle. J. Physiol. (Lond.) 3, 380 (1882).
6. Ringer, S. A further contribution regarding the influence of the different constituents of the blood on the contraction of the heart. J. Physiol. (Lond.) 4, 29 (1883).
7. Locke, F. S. Notiz uber den Einfluss physiologischer Kochsalz-losung auf die elektrische Erregbarkeit von Muskel und Nerv. Zbl. Physiol. 8, 166-167 (1894).
8. Interview by J.-M. Jeng with R. Miledi (Irvine, California, May 2001).
9. Del Castillo, J. & Stark, L. The effect of calcium ions on the motor end-plate potentials. J. Physiol. (Lond.) 116, 507-515 (1952).
10. Del Castillo, J. & Katz, B. The effect of magnesium on the activity of motor nerve endings. J. Physiol. (Lond.) 124, 553-559 (1952).
11. Katz, B. & Miledi, R. The effect of calcium on acetylcholine release from motor nerve terminals. Proc. R. Soc. Lond. B 161, 496-503 (1965).
12. Narahashi, T., Moore, J. W & Scott, W. R. Tetrodotoxin blockage of sodium conductance increase in lobster giant axons. J. Gen. Physiol. 47, 965-974 (1964).
13. Miledi, R. & Slater, C. R. The action of calcium on neuronal synapses in the squid. J. Physiol. (Lond.) 184, 473-498 (1966).
14. Katz, B. & Miledi, R. Input-output relation of a single synapse. Nature 212, 1242-1245 (1966).
15. Bloedel, J., Gage, P. W., Llinas, R. & Quastel, D. M. Transmission across the squid giant synapse in the presence of tetrodotoxin. J. Physiol. (Lond.) 188, 52P-53P (1967).
16. Kusano, K., Livengood, D. R. & Werman, R. Correlation of transmitter release with membrane properties of the presynaptic fiber of the squid giant synapse. J. Gen. Physiol. 50, 2579-2601 (1967).
17. Katz, B. & Miledi, R. The effect of prolonged depolarization on synaptic transfer in the stellate ganglion of the squid. J. Physiol. (Lond.) 216, 503-512 (1971).
18. Miledi, R. Miniature synaptic potentials in squid nerve cells. Nature 212, 1240-1242 (1966).
19. Fantini, B. The history of the Stazione Zoologica Anton Dohrn: an outline [online] (cited 11 Dec. 01) (1999).
20. Katz, B. & Miledi, R. Membrane noise produced by acetylcholine. Nature 226, 962-963 (1970).
21. Katz, B. & Miledi, R. Further observations on acetylcholine noise. Nature New Biol. 232, 124-126 (1971).
22. Llinas, R., Blinks, J. R. & Nicholson, C. Calcium transient in presynaptic terminal of squid giant synapse: detection with aequorin. Science 176, 1127-1129 (1972).
23. Llinas, R., Steinberg, I. Z. & Walton, K. Presynaptic calcium currents and their relation to synaptic transmission: voltage clamp study in squid giant synapse and theoretical model for the calcium gate. Proc. Natl Acad. Sci. USA 73, 2913-2922 (1976).
24. Hille, B. Ionic Channels of Excitable Membranes 2nd edn (Sinauer Associates, Sunderland, Massachusetts, 1992).