Insulin reduces serum glycosylphosphatidylinositol phospholipase D levels in human type I diabetic patients and streptozotocin diabetic rats

Molecular Genetics and Metabolism

Volumn 75, Issue 2, 2002, Pages 154-161

  Schofield, J N ^a   Stephens, J W ^b   Hurel, S J ^b   Bell, K M ^c   DeSouza, J B ^a   Rademacher, T W ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MIDDLESEX HOSPITAL   (United Kingdom)

^c Rodaris Pharmaceuticals   (United Kingdom)

Author keywords

Glycosylphosphatidylinositol; Glycosylphosphatidylinositol phospholipase D; GPI PLD; GPLD1; Inositolphosphoglycan; Insulin; PIG PLD; Streptozotocin; Type I diabetic

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; INSULIN; NEUTRAL INSULIN; PHOSPHOLIPASE D; STREPTOZOCIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE;

ANIMALIA;

EID: 0036354959     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.2001.3287     Document Type: Article

References (29)

1. Phospholipase cleavage of glycosylphosphatidylinositol reconstituted in liposomal membranes
2. Towards the in vitro reconstitution of caveolae. Asymmetric incorporation of glycosylphosphatidylinositol (GPI) and gangliosides into liposomal membranes
3. Inositolphosphoglycan second messengers
4. Cell signalling by inositol phosphoglycans from different species
5. Glycosylphosphatidylinositol-phospholipase D: A possible candidate for the generation of second messengers
6. Structural and functional roles of glycosylphosphatidylinositol in membranes
7. Second messengers of insulin action
8. Chemical mediator or mediators of insulin action: Response to insulin and mode of action
9. Insulin mediators in man: Effects of glucose ingestion and insulin resistance
10. Inositol phosphoglycans in diabetes and obesity: Urinary levels of IPG A-type and IPG P-type, and relationship to pathophysiological changes
11. Stimulation of glycogen synthesis by insulin in human erythroleukemia cells requires the synthesis of glycosylphosphatidylinositol
12. Insulin-stimulated release of lipoprotein lipase by metabolism of its phosphatidylinositol anchor
13. The sulfonylurea drug, glimepiride, stimulates release of glycosylphosphatidylinositol-anchored plasma membrane proteins from 3T3 adipocytes
14. Stimulation of a glycosylphosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport
15. Phosphatidylinositolglycan anchors of membrane proteins: Potential precursors of insulin mediators
16. The distribution of glycosylphosphatidylinositol anchored proteins is differentially regulated by serum and insulin
17. Involvement of phosphatidylinositol and insulin in the coordinate regulation of proteoheparan sulfate metabolism and hepatocyte growth
18. Insulin-induced decrease in 5′-nucleotidase activity in skeletal muscle membranes
19. Insulin activates glycerol-3-phosphate acyltransferase (de novo phosphatidic acid synthesis) through a phospholipid-derived mediator. Apparent involvement of Gi alpha and activation of a phospholipase C
20. Production of glycosylphosphatidylinositol-specific phospholipase D by the islets of Langerhans
21. Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from βTC3 cells
22. Expression and secretion of glycosylphosphatidylinositol-specific phospholipase D by myeloid cell lines
23. Structure and expression of the human glycosylphosphatidylinositol phospholipase D1 (GPLD1) gene
24. Hepatic nuclear factor 3 and high mobility group I/Y proteins bind the insulin response element of the insulin-like growth factor-binding protein-1 promoter
25. Uptake and intracellular stability of glycosylphosphatidylinositol-specific phospholipase D in neuroblastoma cells
26. Distribution of glycosylphosphatidylinositol-specific phospholipase D mRNA in bovine tissue sections
27. Immunolocalization of a glycosylphosphatidylinositol-specific phospholipase D in mast cells found in normal tissue and neurofibromastosis lesions
28. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
29. Seven days of euglycaemic hyperinsulinemai induces insulin resistance for glucose metabolism but not hypertension, elevated catecholamine levels, or increased sodium retention in conscious normal rats