Isoform pattern and AChR aggregation activity of agrin expressed by embryonic chick retinal ganglion neurons

Molecular and Cellular Neuroscience

Volumn 20, Issue 3, 2002, Pages 525-535

  Annies, Maik ^a   Kröger, Stephan ^a  

^a MAX PLANCK INSTITUTE FOR BRAIN RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGRIN; CHOLINERGIC RECEPTOR; ISOPROTEIN; RNA;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CELL POPULATION; CHICK EMBRYO; COCULTURE; CONTROLLED STUDY; EMBRYO; MYOTUBE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA GANGLION CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 0036354730     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2002.1125     Document Type: Article

References (53)

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4. Agrin controls synaptic differentiation in hippocampal neurons
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7. Early stages of motor-neuron differentiation revealed by expression of homeobox gene islet-1
8. The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans
9. Abnormal synapse formation in agrin-depleted hippocampal neurons
10. Partial characterization of chicken Thy-1 glycoprotein by monoclonal antibodies
11. Defective neuromuscular synaptogenesis in agrin-deficient mutant mice
12. Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptor
13. Acetylcholine receptor aggregating activity of agrin isoforms and mapping of the active site
14. Sialic acid inhibits agrin signaling in C2 myotubes
15. A heparan sulfate proteoglycan in developing avian axonal tracts
16. Disruption of the retinal basal lamina during early embryonic development leads to a retraction of vitreal end feet, an increased number of ganglion cells, and aberrant axonal outgrowth
17. Oriented axon outgrowth from avian embryonic retinae in culture
18. Nondirected axonal growth on basal lamina from avian embryonic neural retina
19. A new heparan-sulfate proteoglycan in the extracellular matrix of the developing chick embryo
20. Distribution and substrate properties of agrin, a heparan sulfate proteoglycan of developing axonal pathways
21. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
22. Formation of synaptic specializations in the inner plexiform layer of the developing chick retina
23. Developmental regulation of highly active alternatively spliced forms of agrin
24. Ion channel components of retinal ganglion cells
25. Specific agrin isoforms induce cAMP response element-binding protein phosphorylation in hippocampal neurons
26. Induction by agrin of ectopic and functional postsynaptic-like membrane in innervated muscle
27. Expression, distribution and ultrastructural localization of the synapse-organizing molecule agrin in the mature avian retina
28. Differential distribution of agrin isoforms in the developing and adult avian retina
29. The developing avian retina expresses agrin isoforms during synaptogenesis
30. Formation of functional synaptic connections between cultured cortical neurons from agrin-deficient mice
31. Motor neurons contain agrin-like molecules
32. Agrin is synthesized by retinal cells and colocalizes with gephyrin
33. Neural agrin induces ectopic postsynaptic specializations in innervated muscle fibers
34. Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivo
35. The polysialic acid moiety of the neural cell adhesion molecule is involved in intraretinal guidance of retinal ganglion cell axons
36. An alternative amino-terminus expressed in the central nervous system converts agrin to a type II transmembrane protein
37. Identification of agrin, a synaptic organizing protein from Torpedo electric organ
38. Localization and alternative splicing of agrin mRNA in adult rat brain: Transcripts encoding isoforms that aggregate acetylcholine receptors are not restricted to cholinergic regions
39. Morphogenesis and physiogenesis of the retino-tectal connection in the chicken. II. The retino-tectal synapses
40. Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions
41. Agrin orchestrates synaptic differentiation at the vertebrate neuromuscular junction
42. The agrin gene codes for a family of basal lamina proteins that differ in function and distribution
43. Inhibition of nerve- and agrin-induced acetylcholine receptor clustering on Xenopus muscle cells in culture
44. Synapse formation by hippocampal neurons from agrin-deficient mice
45. Thy-1 expression in the retinotectal system of the chick
46. Selective regulation of agrin mRNA induction and alternative splicing in PC12 cells by Ras-dependent actions of nerve growth factor
47. Cell-specific regulation of agrin RNA splicing in the chick ciliary ganglion
48. Cerebellar granule cells express a specific isoform of agrin that lacks the acetylcholine receptor aggregating activity
49. Tissue- and age-specific expression patterns of alternatively spliced agrin mRNA transcripts in embryonic rat suggest novel developmental roles
50. cDNA that encodes active agrin
51. Inhibition of agrin-induced acetylcholine-receptor aggregation by heparin, heparan sulfate, and other polyanions
52. Neurotrophins regulate agrin-induced postsynaptic differentiation
53. The developing chick isthmooptic nucleus forms a transient efferent projection to the optic tectum