Differential half-maximal effects of human insulin and its analogs for in situ glucose transport and protein synthesis in rat soleus muscle

Metabolism: Clinical and Experimental

Volumn 51, Issue 8, 2002, Pages 1065-1070

  Weinstein, Randi B ^a   Eleid, Noura ^a   LeCesne, Catherine ^a   Durando, Bianca ^a   Crawford, Julie T ^a   Heffner, Michelle ^a   Layton, Christle ^a   O’keefe, Matthew ^a   Robinson, Jennifer ^a   Rudinsky, Suzy ^a   Henriksen, Erik J ^a   Tischler, Marc E ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DEOXY[1,2(3H)]GLUCOSE; 3 METHYLGLUCOSE; DEOXYGLUCOSE; GLUCOSE; HUMAN INSULIN; INSULIN DERIVATIVE; INSULIN RECEPTOR; INSULIN[A8 HISTIDINE B4 HISTIDINE B10 GLUTAMINE B27 HISTIDINE]; INSULIN[B9 ASPARTIC ACID B27 GLUTAMINE]; PHENYLALANINE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; FEMALE; GLUCOSE TRANSPORT; METABOLISM; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SOLEUS MUSCLE;

EID: 0036347914     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2002.34044     Document Type: Article

References (22)

1. Sustained signaling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency
2. Increased response to insulin of glucose metabolism in the 6-day unloaded rat soleus muscle
3. Time course of the response of carbohydrate metabolism to unloading of the soleus
4. Insulin effects in denervated and non-weight-bearing rat soleus muscle
5. Effect of insulin-like factors on glucose transport activity in unweighted rat soleus muscle
6. Effect of soleus unweighting on stimulation of insulin-independent glucose transport activity
7. Insulin attenuates atrophy of unweighted soleus muscle by amplified inhibition of protein degradation
8. Time course of the response of myofibrillar and sarcoplasmic protein metabolism to unweighting of the soleus muscle
9. Different mechanisms of increased proteolysis in atrophy induced by denervation or unweighting of rat soleus muscle
10. Cyclic AMP accumulation and β-adrenergic binding in unweighted and denervated rat soleus muscle
11. Determination of serum proteins by means of the Biuret reaction
12. Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man
13. Failure of insulin infusion to stimulate fractional protein synthesis in type I diabetic patients. Anabolic effect of insulin and decreased proteolysis
14. The effect of insulin infusion and food intake on muscle protein synthesis in postabsorptive rats
15. Responses of protein synthesis in different skeletal muscles to fasting and insulin in rats
16. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
17. Human insulin receptor cDNA: The structural basis for hormone activated transmembrane signaling
18. Alternative splicing of human insulin receptor messenger RNA
19. Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man
20. The rat insulin receptor: Primary structure and conservation of tissue-specific alternative messenger RNA splicing
21. Effect of denervation or unweighting on GLUT-4 protein in rat soleus muscle
22. Hindlimb suspension increases insulin binding and glucose metabolism