Differential expression of CD44(S) and variant isoforms v3, v10 in three-dimensional cultures of mouse melanoma cell lines

Clinical and Experimental Metastasis

Volumn 19, Issue 5, 2002, Pages 445-455

  Shiras, Anjali ^a   Bhosale, Arti ^a   Patekar, Anjali ^a   Shepal, Varsha ^a   Shastry, Padma ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

B16F10; CD44v10; CD44v3; Clone M3; Multi cellular spheroids (MCS)

Indexed keywords

ALPHA CATENIN; CADHERIN; CATENIN; CD44V ANTIGEN; CD44V10 ANTIGEN; CD44V3 ANTIGEN; CELL ADHESION MOLECULE; CYCLIN DEPENDENT KINASE INHIBITOR; PLAKOGLOBIN; PROTEIN P27; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; MELANOMA CELL; METASTASIS; MOUSE; MULTICELLULAR SPHEROID; NONHUMAN; TUMOR GROWTH;

ALPHA CATENIN; ANIMALS; ANTIGENS, CD44; ANTIGENS, NEOPLASM; BETA CATENIN; CADHERINS; CELL ADHESION; CELL AGGREGATION; CELL CULTURE TECHNIQUES; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; CYTOSKELETAL PROTEINS; DESMOPLAKINS; FLOW CYTOMETRY; GAMMA CATENIN; GENE EXPRESSION REGULATION, NEOPLASTIC; MACROMOLECULAR SUBSTANCES; MELANOMA, EXPERIMENTAL; MICE; MICE, NUDE; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; PROTEIN ISOFORMS; SPHEROIDS, CELLULAR; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0036341915     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016305611858     Document Type: Article

References (40)

1. Differential regulation of cyclin-dependent kinase inhibitors in monolayer and spheroid cultures of tumorigenic and nontumorigenic fibroblasts
2. Multi-cellular spheroids as an in vitro tumor model
3. Three dimensional spheroid model in tumor biology
4. Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: Suppression by mutant c-H-ras oncogene expression
5. Cell Culture as spheroids: An approach to multi-cellular resistance
6. Spheroids and cell survival
7. Growth characteristics of human melanoma multi-cellular spheroids in liquid-overlay culture: Comparisons with the parent tumor xenografts
8. Three-dimensional cell cultures: From molecular mechanisms to clinical applications
9. Anchorage - Independent multicellular spheroids as an in vitro model of growth signaling in Ewing tumors
10. Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development
11. Splicing choice from ten variant exons establishes CD44 variability
12. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
13. Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the metastasis associated variant of CD44
14. Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression
15. CD44 variant exon epitopes in primary breast cancer and length of survival
16. Regulated expression of exon v6 containing isoforms of cd44 in man: Down regulation during malignant transformation of tumors of squamo-cellular origin
17. Expression of CD44 in prostate cancer cells
18. Expression of CD44 valiant isoforms in malignant melanoma
19. Expression of CD44 splice variants in human cutaneous melanoma and melanoma cell lines is related to tumor progression and metastatic potential
20. Anoikis and metastatic potential of Cloudman S91 melanoma cells
21. Influence of laminin or fibroblasts upon colony formation in mouse by B16 melanoma cell spheroids: A morphometric analyses
22. Modulation of the metastatic capability in B16 melanoma by cell shape
23. The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate- bearing cells
24. Colocalization of basic fibroblast growth factor and CD44 isoforms containing the variably spliced exon v3 (CD44v3) in normal skin and in epidermal skin cancers
25. The mouse B16 melanoma in a 3-dimensional culture
26. A causal role for E-cadherin in transition from adenoma to carcinoma
27. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
28. E.Cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study
29. E.Cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extra-cellular domain
30. Methylation patterns of the cadherin 5' Cp9 island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression
31. Frequent alterations in E.cadherin and alpha and beta catenin expression in human breast cancer
32. Functional Interaction between E-cadherin and αv containing integrin in carcinoma cells
33. E-cadherin/catenin complex in benign and malignant melanocytic lesions
34. Expression of catenins and p120 cas in melanocytic nevi and cutaneous melanoma: Deficient α-catenin expression is associated with melanoma progression
35. Functional interaction of β-catenin with the transcription factor LEF-2
36. XTCf-3 transcription factor mediates β-catenin induced axis formation in xenopus embryos
37. Stabilization of β-catenin by genetic defects in melanoma cell lines
38. Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
39. Principles of CDK regulation
40. Impact of the cyclin-dependent kinase inhibitor p27 kip1 on resistance of tumor cells to anticancer agents