Study of in vitro stability of liposomes and in vivo antibody response to antigen associated with liposomes containing GM1 after oral and subcutaneous immunization

Journal of Liposome Research

Volumn 12, Issue 1-2, 2002, Pages 13-27

  Fabani, M M ^a   Gargini, R ^a   Taira, M C ^a   Iacono, R ^b   Alonso Romanowski, S ^a  

^a UNIVERSIDAD NACIONAL DE QUILMES   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Antigenicity; Gangliosides; Immunoliposomes; Polymerizable liposomes; Stability

Indexed keywords

1,2 BIS(10,12 TRICOSADIYNOYL)GLYCERO 3 PHOSPHOCHOLINE; ANTIBODY; ANTIGEN; CHOLESTEROL; DRUG VEHICLE; GANGLIOSIDE; LIPOSOME; MEROCYANINE; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG SALIVA LEVEL; DRUG STABILITY; FLUORESCENCE; HYDROPHILICITY; HYDROPHOBICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTIGENS; DRUG DELIVERY SYSTEMS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; G(M1) GANGLIOSIDE; GLUCOSE-6-PHOSPHATE; IMMUNIZATION; KINETICS; LIPID METABOLISM; LIPOSOMES; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; TEMPERATURE; TIME FACTORS; VACCINES;

EID: 0036338666     PISSN: 08982104     EISSN: None     Source Type: Journal    
DOI: 10.1081/LPR-120004772     Document Type: Conference Paper

References (25)

1. Therapeutic applications of colloidal drug carriers
2. Engineering liposomes for drug delivery: Progress and problems
3. Vaccine entrapment in liposomes
4. Plasma-induced leakage of liposome contents
5. Liposomes with prolonged circulation times: Factors affecting uptake by reticulo endothelial and other tissues
6. Liposomes for the sustained drug release in vivo
7. Phospholipids polymers and spectral characteristics
8. Characterization of liposomal formulations for drug delivery
9. Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors
10. Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition
11. Association of blood proteins with large unilamelar liposomes in vivo. Relation to Circulation Lifetimes
12. The reliability of molecular weight determined by dodecylsulfate-polyacrylamide gel electrophoresis
13. Measurement of protein using bicinchoniinic acid
14. Phosphorus assay in column chromatography
15. Glucose-6-phosphate dehydrogenase
16. Generation of one set of monoclonal antibodies specific for a-pathway ganglio-series gangliosides
17. Immunological adjuvants: A role for liposomes
18. Properties of polymeric liposomes formed from mixtures of diacetylenic and saturated phospholipids
19. Detection of lipid peroxidation on erythrocytes using the eximer-forming property of a lipophilic BODIPY fluorescent dye
20. Physicochemical propertes of ox-brain ganglosides
21. Effect of chemically modified GM I neoglycolipid analogs of GM I on liposomes circulation time: Evidence supporting the dysopsonin hypothesis
22. Effect of a selected suppression of the reticulo endothelial system on the distribution of model carrier particles
23. Interaction of merocyanine 540 with nicotinic acetylcholine receptor membranes from Discopyge tschudii electric organ
24. Evaluation of drug targeting strategies and liposomal trafficking
25. Application of liposomes for development of oral vaccines: Study of in vitro stability of liposomes and antibody response to antigen associated with liposomes after oral immunization