Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin

Immunity

Volumn 17, Issue 1, 2002, Pages 95-105

  Sullivan, Barbara A ^a   Kraj, Piotr ^b   Weber, Dominique A ^a   Ignatowicz, Leszek ^b   Jensen, Peter E ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; INSULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; EPITHELIUM CELL; HEMATOPOIESIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; THYMUS; TRANSGENIC MOUSE;

EID: 0036338136     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(02)00343-6     Document Type: Article

References (54)

1. Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm
2. b antigens on cells lacking a functional TAP-2 transporter
3. Identification of a TAP-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen
4. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
5. b
6. Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes
7. Positive selection of an H2-M3 restricted T cell receptor
8. Inefficient positive selection of T cells directed by haematopoietic cells
9. An H2-T MHC class Ib molecule presents Listeria monocytogenes-derived antigen to immune CD8+ cytotoxic T cells
10. b as a key restricting element for Listeria-specific CTLs
11. Remethylation at sites 5′ of the murine Lyt-2 gene in association with shutdown of Lyt-2 expression
12. The selection of M3-restricted T cells is dependent on M3 expression and presentation of N-formylated peptides in the thymus
13. NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells
14. Qa-1 interaction and T cell recognition of the Qa-1 determinant modifier peptide
15. Dominance of a single peptide bound to the class Ib molecule, Qa-1b
16. Ocular immune privilege promoted by the presentation of peptide on tolerogenic B cells in the spleen. II. Evidence for presentation by Qa-1
17. Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures
18. Positive selection of thymocytes
19. Positive selection of T cells
20. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice
21. T cell receptor antagonist peptides induce positive selection
22. A europium fluoroimmunoassay for measuring peptide binding to MHC class I molecules
23. The specific regulation of immune responses by CD8+ T cells restricted by the MHC class Ib molecule, Qa-1
24. Ir-gene control of immunogenicity of insulin and A-chain loop as a carrier determinant
25. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
26. Cassette vectors directing expression of T cell receptor genes in transgenic mice
27. Analysis of Qa-1(b) peptide binding specificity and the capacity of CD94/NKG2A to discriminate between Qa-1-peptide complexes
28. Alpha beta TCRs differ in the degree of their specificity for the positively selecting MHC/peptide ligand
29. Polymorphism of a Qa-1-associated antigen defined by cytotoxic T cells. I. Qed-1a and Qed-1d
30. T cell responses to gram-negative intracellular bacterial pathogens: A role for CD8+ T cells in immunity to Salmonella infection and the involvement of MHC class Ib molecules
31. Molecular mimicry mediated by MHC class Ib molecules after infection with gram-negative pathogens
32. The non-classical MHC class I molecule Qa-1(b) inhibits classical MHC class I-restricted cytotoxicity of cytotoxic T lymphocytes
33. Analysis of T cell receptors specific for recognition of class IB antigens
34. Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice
35. Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules
36. CD94-NKG2A receptors regulate antiviral CD8+ T cell responses
37. Suppression of immune responses by CD8 cells. II. Qa-1 on activated B cells stimulates CD8 cell suppression of T helper 2 responses
38. HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice
39. Single H2Kb, H2Db and double H2KbDb knockout mice: Peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses
40. b class I molecules requires beta 2-microglobulin but is TAP independent
41. b molecule binds to a large subpopulation of murine NK cells
42. Superantigens: Bacterial and viral proteins that manipulate the immune system
43. Response to Listeria monocytogenes in mice lacking MHC class Ia molecules
44. MHC class Ib-restricted CTL provide protection against primary and secondary Listeria monocytogenes infection
45. Cutting edge: Expression of functional CD94/NKG2A inhibitory receptors on fetal NK1.1+Ly-49- cells: A possible mechanism of tolerance during NK cell development
46. CD69 expression during selection and maturation of CD4+8+ thymocytes
47. Transporters associated with antigen processing (TAP)-independent presentation of soluble insulin to alpha/beta T cells by the class Ib gene product, Qa-1(b)
48. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b)
49. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells
50. Major histocompatibility complex (MHC) class I KbDb-/- deficient mice possess functional CD8+ T cells and natural killer cells
51. Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands
52. CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection
53. Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells
54. Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice