Relationship between C-5T Kozak, C807T genotypes and expression of glycoproteins Ibα and Ia-IIa at platelet surface: From genotype to phenotype

Thrombosis and Haemostasis

Volumn 88, Issue 2, 2002, Pages 368-

  Macchi, L ^a   Sorel, N ^a   Brabant, S ^a   Christiaens, L ^a   Mauco, G ^a  

^a POITIERS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA1 GLYCOPROTEIN; CELL ADHESION MOLECULE; GLYCOPROTEIN IB; GLYCOPROTEIN IB ALPHA; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2;

ADULT; AGED; ARTERY THROMBOSIS; CALIBRATION; CELL SURFACE; CONTROLLED STUDY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; IN VITRO STUDY; LETTER; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT;

EID: 0036335976     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1613217     Document Type: Letter

References (5)

1. Platelet polymorphisms in thrombotic disorders
2. Hereditary variation in platelet integrin α2β1 density is associated with two silent polymorphisms in the α2 gene coding sequence
3. Kozak sequence polymorphism of the glycoprotein (GP) Ibα gene is a major determinant of the plasma membrane levels of the platelet GP Ib-IX-V complex
4. A common polymorphism flanking the ATG initiator codon of GpIba does not affect expression and is not a major risk factor for arterial thrombosis
5. The GPIa C807T dimorphism associated with platelet collagen receptor density is not a risk factor for myocardial infarction