A new multiwavelength spectrophotometric method for the determination of the molar absorption coefficients of ionizable drugs

Spectroscopy Letters

Volumn 35, Issue 1, 2002, Pages 9-19

  Hendriksen, Barry A ^a   Sanchez Felix, Manuel V ^b   Tam, Kin Y ^c  

^a ELI LILLY AND COMPANY   (United States)

^b Sciona Ltd   (United Kingdom)

^c Sirius Analytical Instruments Ltd   (United Kingdom)

Author keywords

D PAS; Molar absorption coefficients; Nicotinic acid; P Aminosalicylic acid; Target factor analysis

Indexed keywords

AMINOSALICYLIC ACID; NICOTINIC ACID;

ABSORPTION SPECTROPHOTOMETRY; ANALYTIC METHOD; ARTICLE; DRUG DETERMINATION; INTERMETHOD COMPARISON; IONIZATION; PKA; TITRIMETRY;

EID: 0036329721     PISSN: 00387010     EISSN: None     Source Type: Journal    
DOI: 10.1081/SL-120013129     Document Type: Article

References (18)

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2. Spectrophotometric microdetermination of sulfamethoxazole and trimethoprim using alizarin and quinalizarin
3. Spectrophotometric method for the determination of ritodrine hydrochloride and amoxicillin
4. Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs
5. Multiwavelength spectrophotometric determination of acid dissociation constants part II. First derivative vs. target factor analysis
6. Multiwavelength spectrophotometric determination of acid dissociation constants part III. Resolution of multi-protic ionization systems
7. Multiwavelength spectrophotometric determination of acid dissociation constants part IV. Water-insoluble pyridine derivatives
8. Multiwavelength spectrophotometric determination of acid dissociation constants - Part V: Microconstants and tautomeric ratios of diprotic amphoteric drugs
9. Determination of the number of factors and the experimental error in a data matrix
10. Factor analysis of mass spectra from partially resolved chromatographic peaks using simulated data
11. Theory of the distribution of error eigenvalues resulting from principal component analysis with applications to spectroscopic data
12. Factor analysis using column cross-validation
13. Target factor analysis of the ultraviolet spectra of unresolved liquid chromatography fractions
14. A simplex method for function minimization
15. Accurate measurements of the concentration of hydrogen ions with a glass electrode: Calibration using the prideaux and other universal buffer solutions and a computer-controlled automatic titrator