An improved preparation of 2-azabicyclo[2.2.2]octane

Synthetic Communications

Volumn 32, Issue 13, 2002, Pages 1985-1995

  Chung, John Y L ^a   Ho, Guo Jie ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Bicyclic aza compounds; Hydrogenation; Lactamisation; Reduction

Indexed keywords

4 AMINOBENZOIC ACID; 4 AMINOCYCLOHEXANE CARBOXYLIC ACID; BICYCLO COMPOUND; CYCLOHEXANE; OCTANE; QUINUCLIDINE; TOLUENESULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CIS TRANS ISOMERISM; CYCLIZATION; DRUG MIXTURE; HEATING; HYDROGENATION; PRODUCT RECOVERY; REACTION OPTIMIZATION; REDUCTION; SYNTHESIS;

EID: 0036328854     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1081/SCC-120004848     Document Type: Article

References (15)

1. Aza Diels-Alder reactions in aqueous solution: Cyclocondensation of dienes with simple iminium salts generated under mannich conditions
2. A new isoquinuclidine synthesis
3. A new route to dl-dioscorone
4. Aqueous aza Diels-Alder reactions catalyzed by lanthanide (III) trifluoromethanesulfonates
5. Reaction of chlorosulphonyl isocyanate with 1,3-dienes. Control of 1,2- and 1,4-addition pathways and the synthesis of aza- and oxa-bicyclic systems
6. Studies on 1-alkyl-2(1H)-pyridone derivatives. X. The Diels-Alder reaction of 1-methyl-2(1H)-pyridone with maleic anhydride
7. Ein gutes losungsmittel fur die molekular-gewichtsbestimmung nach rast
8. 3-Isoquinuclidone
9. Isoquinuclidine-based expectorants. Synthesis and biological activities of N-alkoxybenzylisoquinuclidines
10. Approaches towards the synthesis of fluoro(cyclo)alkylamines
11. Properties of sodium bis(2-methoxyethoxy)aluminum hydride IV. Reduction of oximes, amides, lactams, imides, and nitriles
12. Properties of sodium bis(2-methoxyethoxy)aluminum hydride. I. Reduction of some organic functional groups
13. Reductions with VITRIDE® reducing agent
14. VITRIDE® reducing agent