TLC analysis of formaldehyde produced by metabolic N-demethylation

Journal of Liquid Chromatography and Related Technologies

Volumn 25, Issue 10-11, 2002, Pages 1589-1598

  Kalaand́sz, Huba ^a   Szarvas, Tibor ^b   Szarkane Bolehovszky, Andrea ^a   Lengyel, Jozsef ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b Institute of Isotopes   (Hungary)

Author keywords

( ) Deprenyl; Formaldehyde; Microsomal metabolism; Thin layer chromatography; TLC

Indexed keywords

METABOLISM; X RAY FILMS;

DEMETHYLATION;

FORMALDEHYDE;

FORMALDEHYDE;

ANALYTIC METHOD; ARTICLE; AUTORADIOGRAPHY; DEAMINATION; DEMETHYLATION; LIVER MICROSOME; METABOLIC ACTIVATION; MICROSOME MEMBRANE; MONITORING; SAMPLING; THIN LAYER CHROMATOGRAPHY;

EID: 0036328568     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-120005706     Document Type: Article

References (11)

1. Carrier displacement chromatography for identification of deprenyl and its metabolites
2. Chromatographic studies on the binding, action and metabolism of (-)-deprenyl
3. Urinary excretion of deprenyl metabolites
4. GC-SIM study of deprenyl metabolism
5. Formaldehyde cycle and the natural formaldehyde generators and capturers
6. Quantitative determination of formaldehyde in hard tissues of teeth
7. Increase of formation of methylamine and formaldehyde in vivo after administration of nicotine and the potential cytotoxicity
8. The dynamics of drug adsorbtion, distribution and elimination
9. Drug biotransformation
10. Fate of the drug in the body, pharmocokinetics
11. Formaldehyde and the phases of stress syndrome