Insulin restores expression of adenosine kinase in streptozotocin-induced diabetes mellitus rats

Molecular and Cellular Biochemistry

Volumn 236, Issue 1-2, 2002, Pages 163-171

  Sakowicz, Monika ^a   Pawelczyk, Tadeusz ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Adenosine; Adenosine kinase; Diabetes; Insulin

Indexed keywords

ADENOSINE KINASE; GLUCOSE; INSULIN; LONG ACTING DRUG; MESSENGER RNA; NUCLEOSIDE; PROTEIN; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HEART; KIDNEY; LIVER; MALE; NONHUMAN; NUCLEOSIDE TRANSPORT; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; TIME;

ADENOSINE; ADENOSINE KINASE; ANIMALS; CYTOSOL; DIABETES MELLITUS, EXPERIMENTAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYPOGLYCEMIC AGENTS; IMMUNOBLOTTING; INSULIN; LIVER; MYOCARDIUM; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; STREPTOZOCIN; TIME FACTORS; TISSUE DISTRIBUTION; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0036327874     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016163517896     Document Type: Article

References (65)

1. Predisposition to hypertension and susceptibility to renal disease in insulin-dependent diabetes mellitus
2. Clinical features and investigation of diabetic somatic peripheral neuropathy
3. Diabetes mellitus and hypertension
4. Altered myocardial mechanics in diabetic rats
5. Diabetes mellitus induces changes in cardiac myosin in the rat
6. Light and electron microscopy study of akin capillaries of diabetes
7. Diabetic nephropathy in type I (insulin-dependent) diabetes: An epidemiological study
8. Early functional and morphological changes in diabetic nephropathy
9. Glomerular hemodynamic and structural alterations in experimental diabetes mellitus
10. Abnormalities of endoneurial microvessels and sural nerve pathology in diabetic neuropathy
11. Experimental diabetic neuropathy: An update
12. The effect of prostoglandins E1, E2 and F2 and indomethacin on the sensitivity of glycolysis and glycogen synthesis to insulin in stripped soleus muscles of the rat
13. Recent developments in metabolism that impinge on research into the nature and treatment of diabetes mellitus
14. Facilitation by adenosine of the action of insulin on the accumulation of adenosine 3′:5′-monophosphate, lipolysis, and glucose oxidation in isolated fat cells
15. Effect of analogues of adenosine and methyl xanthines on insulin sensitivity in soleus muscle of the rat
16. Adenosine effects on glucose oxidation of adipocytes isolated from streptozotocin-diabetic rats
17. Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contraction
18. Role of adenosine in insulin-stimulated release of leptin from isolated while adipocytes of Wistar rats
19. Adenosine reversal of in vivo hepatic responsiveness to insulin
20. The transmethylation pathway as a source for adenosine in the isolated guinea-pig heart
21. Mechanism of elevation of adenosine levels in anoxic hepatocytes
22. Interstitial adenosine and cellular metabolism during beta-adrenergic stimulation of the in situ rabbit heart
23. Adenosine receptors and signaling in the kidney
24. Regulation of adenosine metabolism by 5′-nucleotidase
25. Adenosine receptors
26. Molecular cloning and characterization of a novel adenosine receptor: The A3 adenosine receptor
27. Increased responses to adenosine in isolated left atria from streptozotocin-diabetic rats: Evidence for the involvement of hypothyroidism
28. Altered cellular signalling and decreased platelet sensitivity to adenosine in insulin-dependent diabetic patients with proliferative retinopathy
29. Changes in adenosine sensitivity in the hippocampus of rats with streptozotocin-induced diabetes
30. Increased sensitivity of the renal vasculature to adenosine in streptozotocin-induced diabetes mellitus rats
31. Adenosine-induced renal vasoconstriction in diabetes mellitus rats: Role of nitric oxide
32. Altered relaxant responses to adenosine and adenosine 5′ triphosphate in the corpus cavernosum from men and rats with diabetes
33. Renal handling and metabolism of adenosine in diabetic rats
34. Decreased expression of adenosine kinase in streptozotocin-induced diabetes mellitus rats
35. The distribution of enzymes involved in purine metabolism in rat kidney
36. The FHIT gene at 3p14.2 is abnormal in breast carcinomas
37. Expression level of adenosine kinase in rat tissues. Lack of phosphate effect on the enzyme activity
38. Cloning and expression of the adenosine kinase gene from rat and human tissues
39. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
40. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
41. Chemiluminescent determination of adenosine, inosine and hypoxanthine/xanthine
42. The insulin signaling system and the IRS proteins
43. Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin
44. Glucose regulation of gene transcription
45. Insulin stimulation of pyruvate dehydrogenase in isolated plasma membrane-mitochondrial mixture occurs by activation of pyruvate dehydrogenase phosphatase
46. The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
47. Glycation and inactivation of human Cu-Zn-superoxide dismutase. Identification of the in vitro glycated sites
48. Glycation and inactivation of sorbitol dehydrogenase in normal and diabetic rats
49. Adenine nucleotide metabolism in hearts of diabetic rats. Comparison to diaphragm, liver, and kidney
50. Inhibition of adenosine metabolism increases myocardial interstitial adenosine concentration and coronary flow
51. Rapid turnover of the AMP-adenosine metabolic cycle in the guinea pig heart
52. Mechanism of elevation of adenosine levels in anoxic hepatocytes
53. Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices
54. Nucleoside and nucleobase transport systems of mammalian cells
55. Nucleoside transporters: Molecular biology and implications for therapeutic development
56. Adenosine transport in cultured human umbilical vein endothelial cells is reduced in diabetes
57. Reduced adenosine uptake accelerates ischemic block of population spikes in hippocampal slices from streptozotocin-treated diabetic rats
58. G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization
59. The role of receptor structure in determining adenosine receptor activity
60. Differential desensitization of A1 adenosine receptor-mediated inhibition of cardiac myocyte contractility and adenylate cyclase activity. Relation to the regulation of receptor affinity and density
61. Molecular basis for subtype-specific desensitization of inhibitory adenosine receptors. Analysis of himeric A1-A3 adenosine receptor
62. Prolonged in vitro exposure of rat brain slices to adenosine analogues: Selective desensitization of adenosine A1 but not A2 receptors
63. Prolonged exposure to 5′-N ethyl-carboxamidoadenosine (NECA) does not affect the adenosine A2A mediated vasodilatation in porcine coronary arteries
64. The antiadrenergic effect of cyclopentyladenosine on myocardial contractility is reduced in vivo in diabetic rats
65. Contrasting effects of streptozotocin-induced diabetes on the in vitro relaxant properties of adenosine in rat pancreatic vascular bed and thoracic aorta