Oral versus systemic antibiotic prophylaxis in elective colon surgery: A randomized study and meta-analysis send a message from the 1990s

Canadian Journal of Surgery

Volumn 45, Issue 3, 2002, Pages 173-180

  Lewis, Ronald T ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; METRONIDAZOLE; NEOMYCIN;

AGED; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CLINICAL TRIAL; COLON SURGERY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ELECTIVE SURGERY; FEMALE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SURGICAL INFECTION; WOUND INFECTION;

ADIPOSE TISSUE; ADMINISTRATION, ORAL; AGED; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; BACTERIA; COLON; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; SURGICAL PROCEDURES, ELECTIVE; SURGICAL WOUND INFECTION;

EID: 0036324555     PISSN: 0008428X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Postoperative wound infection: A postoperative study of determinant factors and prevention
2. The use of antibiotics in general surgery
3. A survey of clinical trials of antibiotic prophylaxis in colon surgery: Evidence against further use of no treatment controls
4. Preoperative prophylactic cephalothin fails to control septic complications of colorectal operations: Results of a controlled clinical trial. A Veterans Administration cooperative study
5. Preoperative bowel preparation: A survey of colon and rectal surgeons
6. Survey of antibiotic prophylaxis in gastrointestinal surgery in Scotland
7. A survey of antimicrobial prophylaxis in elective colorectal surgery in New Zealand
8. Pharmacokinetics and tissue penetration of a single 1000 milligram intravenous dose of metronidazole for antibiotic prophylaxis of colorectal surgery
9. CDC definitions of nosocomial surgical site infections, 1992: A modification of CDC definitions of surgical wound infections
10. Reduction in the incidence of Clostridium difficile associated diarrhea in an acute care hospital and a skilled nursing facility following replacement of electronic thermometers with single use disposables
11. The etiology and management of diarrhea in the gynecologic oncology patient
12. Assessing the quality of randomized clinical trials: Is blinding necessary?
13. Parenteral antibiotics in elective colon surgery? A prospective, controlled clinical study
14. Single dose parenteral antibiotics as prophylaxis against wound infections in colonic operations
15. Comparison between oral and systemic antibiotics and their combined use for the prevention of complications in colorectal surgery
16. Cefoxitin versus erythromycin, neomycin, and cefazolin in colorectal operations
17. Systemic versus systemic plus oral chemoprophylaxis in elective colorectal surgery
18. Prophylactic antibiotics in elective colorectal surgery
19. Factors involved in antibiotic selection in elective colon and rectal surgery
20. Do preoperative oral antibiotics influence sepsis rates following elective colorectal surgery in patients receiving perioperative intravenous prophylaxis
21. Metronidazole vs erythromycin, neomycin, and cefazolin in prophylaxis for colonic surgery
22. Antibiotics in elective colon surgery
23. Selective decontamination of the colon before elective colorectal surgery
24. Value of oral antibiotic prophylaxis in colorectal surgery
25. Intestinal antisepsis in surgery
26. Preoperative preparation of the colon
27. Effect of preoperative antibiotic regimen on development of infection after intestinal surgery: Prospective, randomized, double-blind study
28. Preoperative oral antibiotics reduce septic complications of colon operations: Results of a prospective, randomized, double-blind clinical study
29. The value and duration of defence reactions of the skin to primary lodgement of bacteria
30. The effective period of preventive antibiotic action in experimental incisions and dermal lesions
31. Prevention of anaerobic infection in surgery of the colon
32. Wound infection: A controlled clinical and experimental demonstration of synergy between aerobic (Escherichia coli) and anaerobic (Bacteroidesfragilis) bacteria
33. Are first-generation cephalosporins effective for antibiotic prophylaxis in elective surgery of the colon?
34. Comparison between systemic and oral anti-microbial prophylaxis in colorectal surgery
35. The influence of oral versus parenteral preoperative metronidazole on sepsis following colon surgery
36. Protection of colonic anastomoses with antibiotics
37. Clostridium difficile-associated diarrhea follows perioperative prophylaxis with cefoxitin
38. Efficacy of cefazolin, cefamandole and gentamicin as prophylactic agents in cardiac surgery; results of a prospective randomized double blind trial in 1030 patients
39. Leg wound complications associated with coronary revascularization
40. The impact of surgical site infections in the 1990s: Attributable mortality, excess length of hospitalization, and extra costs
41. Effects of prophylactic antibiotics on wound infection after elective colon and rectal surgery 1960 to 1980
42. Is neomycin necessary for bowel preparation in surgery of the colon? Oral neomycin plus erythromycin versus erythromycin-metronidazole
43. Metaanalysis of randomized controlled studies