Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input

Brain

Volumn 125, Issue 7, 2002, Pages 1496-1509

  Bartsch, Thorsten ^a   Goadsby, Peter J ^a,b  

^a NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Central sensitization; Convergence; Dura; Greater occipital nerve; Headache; Pain referral

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ELECTROSTIMULATION; GREATER OCCIPITAL NERVE; HEADACHE; NERVE; NERVE CELL; NERVE STIMULATION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTIVE FIELD; SENSORY NERVE;

EID: 0036317610     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awf166     Document Type: Article

References (73)

1. Specialization of sensorimotor organization in the neck muscle system
2. Neck muscle and trigeminal input to the upper cervical cord and lower medulla of the cat
3. Nerve fibres and their terminals in the dura mater encephali of the rat
4. Convergence of occipital nerve and superior sagittal sinus input in the cervical spinal cord of the cat
5. Headache and the greater occipital nerve
6. Central projections from cat suboccipital muscles: A study using transganglionic transport of horseradish peroxidase
7. Stimulation of the greater occipital nerve (GON) enhances responses of dural responsive convergent neurons in the trigemino-cervical complex in the rat
8. Headache and the neck
9. The cervical zygapophysial joints as a source of neck pain
10. Cervicogenic headache, migraine without aura and tension-type headache. Diagnostic blockade of the greater occipital and supra-orbital nerves
11. Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons
12. The development of cutaneous allodynia during a migraine attack
13. Opioid control of the release of calcitonin gene-related peptide-like material from the rat spinal cord in vivo
14. Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input
15. Secondary cluster headache responsive to sumatriptan
16. Dural vasodilation causes a sensitization of rat caudal trigeminal neurones in vivo that is blocked by a 5-HT1B/1D agonist
17. Responses of feline trigeminal spinal tract nucleus neurons to stimulation of the middle meningeal artery and sagittal sinus
18. Central acute pain mechanisms
19. Ameboid receptive fields of cells in laminae 1, 2 and 3
20. Recordings from brain stem neurons responding to chemical stimulation of the subarachnoid space
21. Convergence of meningeal and facial afferents onto trigeminal brainstem neurons: An electrophysiological study in rat and man
22. Experiments on pain referred from deep somatic tissues
23. The pathophysiology of headache
24. The distribution of trigeminovascular afferents in the non-human primate brain Macaca nemestrina: A c-fos immunocytochemical study
25. Stimulation of the greater occipital nerve increases metabolic activity in the trigeminal nucleus caudalis and cervical dorsal horn of the cat
26. Migraine: Current understanding and treatment
27. Wind-up of spinal cord neurones and pain sensation: Much ado about something?
28. Appearance of new receptive fields in rat dorsal horn neurons following noxious stimulation of skeletal muscle: A model for referral of muscle pain?
29. Stimulation of craniofacial muscle afferents induces prolonged facilitatory effects in trigeminal nociceptive brain-stem neurones
30. Role of the upper cervical roots in the production of pain in the head
31. Vertebral artery dissection presenting as cerebellar infarction
32. Trigeminal primary afferents project bilaterally to dorsal horn and ipsilaterally to cerebellum, reticular formation, and cuneate, solitary, supratrigeminal and vagal nuclei
33. Expression of c-Fos-like immunoreactivity in the caudal medulla and upper cervical spinal cord following stimulation of the superior sagittal sinus in the cat
34. A mechanism to account for frontal headache in cases of posterior fossa tumours
35. Central relationships of trigeminal and cervical primary afferents in the spinal cord and medulla
36. Trigeminal and cervical volleys
37. 'Mirror pain' and indications of bilateral dorsal horn activation in response to unilateral nociception
38. Trigeminal projections to supratentorial pial and dural blood vessels in cats demonstrated by horseradish peroxidase histochemistry
39. Receptive fields of rat lamina 1 projection cells move to incorporate a nearby region of injury
40. Responses of single dorsal cord cells to peripheral cutaneous unmyelinated fibres
41. Nociception from skeletal muscle in relation to clinical muscle pain
42. Axotomized and intact muscle afferents but no skin afferents develop ongoing discharges of dorsal root ganglion origin after peripheral nerve lesion
43. Spinal cord cytoarchitecture
44. Alterations produced by cortisol in the spontaneous activity and responsiveness to sensory stimuli of single cells in the tuberal hypothalamus of the rat
45. Central distribution of cervical primary afferents in the rat, with emphasis on proprioceptive projections to vestibular, perihypoglossal, and upper thoracic spinal nuclei
46. Differences in the chemical expression of rat primary afferent neurons which innervate skin, muscle or joint
47. Neuroplasticity induced by tooth pulp stimulation in trigeminal subnucleus oralis involves NMDA receptor mechanisms
48. Central distribution of trigeminal and upper cervical primary afferents in the rat studied by anterograde transport of horseradish peroxidase conjugated to wheat germ agglutinin
49. The splenius capitis muscle of the rat, architecture and histochemistry, afferent and efferent innervation as compared with that of the quadriceps muscle
50. Referred pain after painful stimulation of the greater occipital nerve in humans: Evidence of convergence of cervical afferences on trigeminal nuclei
51. Headache and the cervical spine: A critical review
52. Experimental studies on headache. Pain sensitive structures of the head and their significance in headache
53. Motor and sensory fibres of neck muscle nerves in the cat
54. Pathophysiology of pain
55. Synaptic mechanisms of hyperalgesia
56. Afferent and spinal mechanisms of joint pain
57. Response properties of trigeminal brain stem neurons with input from dura mater encephali in the rat
58. Afferent projections of the rat major occipital nerve studied by transganglionic transport of HRP
59. Convergence of cutaneous, tooth pulp, visceral, neck and muscle afferents onto nociceptive and non-nociceptive neurones in trigeminal subnucleus caudalis (medullary dorsal horn) and its implications for referred pain
60. Distribution of fos-like immunoreactivity in the medullary and upper cervical dorsal horn produced by stimulation of dural blood vessels in the rat
61. Sensitization of meningeal sensory neurons and the origin of headaches
62. Small-caliber afferent inputs produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A-fibers in the neonatal rat spinal cord in vitro
63. Reduction of calcitonin gene-related peptide in the jugular blood following electrical stimulation of rat greater occipital nerve
64. Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat
65. Role of opioid receptors in neurogenic dural vasodilation and sensitization of trigeminal neurones in anaesthetized rats
66. Referral of pain from dural stimulation in man
67. Windup and central sensitization are not equivalent
68. Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord
69. Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat
70. Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent activation
71. Differential effects of cutaneous and deep application of inflammatory irritant on mechanoreceptive field properties of trigeminal brain stem nociceptive neurons